LDLR Antibody (C7) - BSA Free | Novus Biologicals NBP1-78159 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

LDLR Antibody (C7) - BSA Free

catalog :

NBP1-78159

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

reactivity :

human, mouse, rat, bovine

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, radioimmunoassay, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, proximity ligation assay

more info or order :

Novus Biologicals product webpage

citations: 34

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; human western blot; human	Maxwell K, Fisher E, Breslow J. Overexpression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment. Proc Natl Acad Sci U S A. 2005;102:2069-74 pubmed
immunocytochemistry; human	Gillian Daniel D, Bates P, Tebon A, Attie A. Endoplasmic reticulum localization of the low density lipoprotein receptor mediates presecretory degradation of apolipoprotein B. Proc Natl Acad Sci U S A. 2002;99:4337-42 pubmed
ELISA; human western blot; human	Hofer F, Gruenberger M, Kowalski H, Machat H, Huettinger M, Kuechler E, et al. Members of the low density lipoprotein receptor family mediate cell entry of a minor-group common cold virus. Proc Natl Acad Sci U S A. 1994;91:1839-42 pubmed
western blot; human	Somia N, Zoppe M, Verma I. Generation of targeted retroviral vectors by using single-chain variable fragment: an approach to in vivo gene delivery. Proc Natl Acad Sci U S A. 1995;92:7570-4 pubmed
radioimmunoassay; human immunocytochemistry; human	Beisiegel U, Schneider W, Goldstein J, Anderson R, Brown M. Monoclonal antibodies to the low density lipoprotein receptor as probes for study of receptor-mediated endocytosis and the genetics of familial hypercholesterolemia. J Biol Chem. 1981;256:11923-31 pubmed
radioimmunoassay; human immunoprecipitation; human	Leitersdorf E, Hobbs H, Fourie A, Jacobs M, van der Westhuyzen D, Coetzee G. Deletion in the first cysteine-rich repeat of low density lipoprotein receptor impairs its transport but not lipoprotein binding in fibroblasts from a subject with familial hypercholesterolemia. Proc Natl Acad Sci U S A. 1988;85:7912-6 pubmed
	Lee E, Jung Y, Park Y, Lim S, Choi Y, Lee S, et al. A distinct astrocyte subtype in the aging mouse brain characterized by impaired protein homeostasis. Nat Aging. 2022;2:726-741 pubmed publisher
	Horlock A, Ormsby T, Clift M, Santos J, Bromfield J, Sheldon I. Cholesterol supports bovine granulosa cell inflammatory responses to lipopolysaccharide. Reproduction. 2022;164:109-123 pubmed publisher
	Riad A, Lengyel Zhand Z, Zeng C, Weng C, Lee V, Trojanowski J, et al. The Sigma-2 Receptor/TMEM97, PGRMC1, and LDL Receptor Complex Are Responsible for the Cellular Uptake of Aβ42 and Its Protein Aggregates. Mol Neurobiol. 2020;57:3803-3813 pubmed publisher
	Xu Y, Zhu Y, Bawa F, Hu S, Pan X, Yin L, et al. Hepatocyte-Specific Expression of Human Carboxylesterase 1 Attenuates Diet-Induced Steatohepatitis and Hyperlipidemia in Mice. Hepatol Commun. 2020;4:527-539 pubmed publisher
	Langhaug L, Finnegan A, Schenk K, Puffer E, Rusakaniko S, Green E. Caregiver self-efficacy to talk about sex predicts conversations about HIV transmission risk with perinatally infected young people in Zimbabwe. AIDS Care. 2020;32:1524-1528 pubmed publisher
	Omer L, Hindi L, Militello G, Stivers K, Tien K, Boyd N. Familial hypercholesterolemia class II low-density lipoprotein receptor response to statin treatment. Dis Model Mech. 2020;13: pubmed publisher
	Xu Y, Xu Y, Zhu Y, Sun H, Juguilon C, Li F, et al. Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis. Mol Ther. 2020;28:202-216 pubmed publisher
	Zhu X, Gan Schreier H, Otto A, Cheng Y, Staffer S, Tuma Kellner S, et al. iPla2β deficiency in mice fed with MCD diet does not correct the defect of phospholipid remodeling but attenuates hepatocellular injury via an inhibition of lipid uptake genes. Biochim Biophys Acta Mol Cell Biol Lipids. 2019;1864:677-687 pubmed publisher
	Riad A, Zeng C, Weng C, Winters H, Xu K, Makvandi M, et al. Sigma-2 Receptor/TMEM97 and PGRMC-1 Increase the Rate of Internalization of LDL by LDL Receptor through the Formation of a Ternary Complex. Sci Rep. 2018;8:16845 pubmed publisher
	Pinto P, Da Silva K, Iborra R, Okuda L, Gomes Kjerulf D, Ferreira G, et al. Exercise Training Favorably Modulates Gene and Protein Expression That Regulate Arterial Cholesterol Content in CETP Transgenic Mice. Front Physiol. 2018;9:502 pubmed publisher
	Motherwell J, Anderson C, Murfee W. Endothelial Cell Phenotypes are Maintained During Angiogenesis in Cultured Microvascular Networks. Sci Rep. 2018;8:5887 pubmed publisher
	Baktash Y, Madhav A, Coller K, Randall G. Single Particle Imaging of Polarized Hepatoma Organoids upon Hepatitis C Virus Infection Reveals an Ordered and Sequential Entry Process. Cell Host Microbe. 2018;23:382-394.e5 pubmed publisher
	Knettel B, Rugira J, Cornett J. Mental Health Diagnostic Frameworks, Imputed Causes of Mental Illness, and Alternative Treatments in Northern Tanzania: Exploring Mental Health Providers' Perspectives. Cult Med Psychiatry. 2018;42:483-503 pubmed publisher
	Sato M, Miyoshi K, Nakamura S, Ohtsuka M, Sakurai T, Watanabe S, et al. Efficient Generation of Somatic Cell Nuclear Transfer-Competent Porcine Cells with Mutated Alleles at Multiple Target Loci by Using CRISPR/Cas9 Combined with Targeted Toxin-Based Selection System. Int J Mol Sci. 2017;18: pubmed publisher
	Maddaloni E, Xia Y, Park K, D Eon S, Tinsley L, St Louis R, et al. High density lipoprotein modulates osteocalcin expression in circulating monocytes: a potential protective mechanism for cardiovascular disease in type 1 diabetes. Cardiovasc Diabetol. 2017;16:116 pubmed publisher
	Bartelt A, John C, Schaltenberg N, Berbee J, Worthmann A, Cherradi M, et al. Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport. Nat Commun. 2017;8:15010 pubmed publisher
	Tsugita M, Morimoto N, Tashiro M, Kinoshita K, Nakayama M. SR-B1 Is a Silica Receptor that Mediates Canonical Inflammasome Activation. Cell Rep. 2017;18:1298-1311 pubmed publisher
	Chen H, Chen P, Wu M, Tai M, Yen J. Tanshinone IIA Modulates Low Density Lipoprotein Uptake via Down-Regulation of PCSK9 Gene Expression in HepG2 Cells. PLoS ONE. 2016;11:e0162414 pubmed publisher
	Conlon D, Thomas T, Fedotova T, Hernandez Ono A, Di Paolo G, Chan R, et al. Inhibition of apolipoprotein B synthesis stimulates endoplasmic reticulum autophagy that prevents steatosis. J Clin Invest. 2016;126:3852-3867 pubmed publisher
	Granato M, Zompetta C, Vescarelli E, Rizzello C, Cardi A, Valia S, et al. HCV derived from sera of HCV-infected patients induces pro-fibrotic effects in human primary fibroblasts by activating GLI2. Sci Rep. 2016;6:30649 pubmed publisher
	Pasterk L, Lemesch S, Leber B, Trieb M, Curcic S, Stadlbauer V, et al. Oxidized plasma albumin promotes platelet-endothelial crosstalk and endothelial tissue factor expression. Sci Rep. 2016;6:22104 pubmed publisher
	Vaisman B, Vishnyakova T, Freeman L, Amar M, Demosky S, Liu C, et al. Endothelial Expression of Scavenger Receptor Class B, Type I Protects against Development of Atherosclerosis in Mice. Biomed Res Int. 2015;2015:607120 pubmed publisher
	Pena F, Jansens A, van Zadelhoff G, Braakman I. Calcium as a crucial cofactor for low density lipoprotein receptor folding in the endoplasmic reticulum. J Biol Chem. 2010;285:8656-64 pubmed publisher
	Roosendaal S, Kerver J, Schipper M, Rodenburg K, Van der Horst D. The complex of the insect LDL receptor homolog, lipophorin receptor, LpR, and its lipoprotein ligand does not dissociate under endosomal conditions. FEBS J. 2008;275:1751-66 pubmed publisher
	Blasiole D, Oler A, Attie A. Regulation of ApoB secretion by the low density lipoprotein receptor requires exit from the endoplasmic reticulum and interaction with ApoE or ApoB. J Biol Chem. 2008;283:11374-81 pubmed publisher
	Nguyen A, Hirama T, Chauhan V, MacKenzie R, Milne R. Binding characteristics of a panel of monoclonal antibodies against the ligand binding domain of the human LDLr. J Lipid Res. 2006;47:1399-405 pubmed
	Jaworska Wilczyńska M, Wilczynski G, Engel W, Strickland D, Weisgraber K, Askanas V. Three lipoprotein receptors and cholesterol in inclusion-body myositis muscle. Neurology. 2002;58:438-45 pubmed
	Jørgensen M, Jensen O, Holst H, Hansen J, Corydon T, Bross P, et al. Grp78 is involved in retention of mutant low density lipoprotein receptor protein in the endoplasmic reticulum. J Biol Chem. 2000;275:33861-8 pubmed

product information

master code :

NBP1-78159

SKU :

NBP1-78159

product name :

LDLR Antibody (C7) - BSA Free

unit size :

0.1 ml (also 0.025 ml)

description :

The LDLR Antibody (C7) - BSA Free from Novus is a mouse monoclonal antibody to LDLR. This antibody reacts with bovine,human,mouse,porcine,rat. The LDLR Antibody (C7) - BSA Free has been validated for the following applications: ELISA,Flow Cytometry,Immunoprecipitation,Western Blot,Immunohistochemistry-Frozen,In vitro assay,Radioimmunoassay,Electron Microscopy,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin,Proximity Ligation Assay.

target :

LDLR

category :

Primary Antibodies

buffer :

Tris-Glycine, 0.15M NaCl

clonality :

Monoclonal

clone :

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Partially purified bovine LDL receptor [Swiss-Prot# P01131].

isotype :

IgG2b

purity :

Protein G purified

species :

Bovine,Human,Mouse,Porcine,Rat

gene symbol :

LDLR

accessionNumbers :

P01130, P01131

applications :

ELISA,Flow Cytometry,Immunoprecipitation,Western Blot,Immunohistochemistry-Frozen,In vitro assay,Radioimmunoassay,Electron Microscopy,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin,Proximity Ligation Assay

USD :

409 USD

alt names :

FH, FHC, LDL receptor, LDLCQ2, low density lipoprotein receptor, low-density lipoprotein receptor, low-density lipoprotein receptor class A domain-containing protein 3

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage