XBP1 Antibody - BSA Free | Novus Biologicals NBP1-77681 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

XBP1 Antibody - BSA Free

catalog :

NBP1-77681

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - paraffin section, proximity ligation assay

more info or order :

Novus Biologicals product webpage

citations: 21

Published Application/Species/Sample/Dilution	Reference
proximity ligation assay; human; 1:1000; fig 4c	Lin J, Liu H, Fukumoto T, Zundell J, Yan Q, Tang C, et al. Targeting the IRE1α/XBP1s pathway suppresses CARM1-expressing ovarian cancer. Nat Commun. 2021;12:5321 pubmed publisher
	Weaver F, White E, Peek A, Nurse C, Austin R, Igdoura S. 4-Phenylbutyric acid mitigates ER stress-induced neurodegeneration in the spinal cords of a GM2 gangliosidosis mouse model. Hum Mol Genet. 2025;34:32-46 pubmed publisher
	de Zeeuw P, Treps L, Garc xed a Caballero M, Harjes U, Kalucka J, De Legher C, et al. The gluconeogenesis enzyme PCK2 has a non-enzymatic role in proteostasis in endothelial cells. Commun Biol. 2024;7:618 pubmed publisher
	Correa Medero L, Jankowski S, Hong H, Armas N, Vijendra A, Reynolds M, et al. ER-associated degradation adapter Sel1L is required for CD8+ T cell function and memory formation following acute viral infection. Cell Rep. 2024;43:114156 pubmed publisher
	Ahuja N, Gupta S, Arora R, Bhagyaraj E, Tiwari D, Kumar S, et al. Nr1h4 and Thrb ameliorate ER stress and provide protection in the MPTP mouse model of Parkinson's. Life Sci Alliance. 2024;7: pubmed publisher
	Denolly S, Guo H, Martens M, P x142 aszczyca A, Scaturro P, Prasad V, et al. Dengue virus NS1 secretion is regulated via importin-subunit β1 controlling expression of the chaperone GRp78 and targeted by the clinical drug ivermectin. MBio. 2023;14:e0144123 pubmed publisher
	Espina M, Di Franco N, Bra xf1 as Navarro M, Navarro I, Brito V, López Molina L, et al. The GRP78-PERK axis contributes to memory and synaptic impairments in Huntington's disease R6/1 mice. Neurobiol Dis. 2023;184:106225 pubmed publisher
	Lombardi S, Goldman A, Tang H, Kossenkov A, Liu H, Zhou W, et al. Targeting Fatty Acid Reprogramming Suppresses CARM1-expressing Ovarian Cancer. Cancer Res Commun. 2023;3:1067-1077 pubmed publisher
	Pandit M, Kil Y, Ahn J, Pokhrel R, Gu Y, Mishra S, et al. Methionine consumption by cancer cells drives a progressive upregulation of PD-1 expression in CD4 T cells. Nat Commun. 2023;14:2593 pubmed publisher
	Navas Madro xf1 al M, Almendra Pegueros R, Puertas Umbert L, Jim xe9 nez Altay xf3 F, Julve J, P xe9 rez B, et al. Targeting mitochondrial stress with Szeto-Schiller 31 prevents experimental abdominal aortic aneurysm: Crosstalk with endoplasmic reticulum stress. Br J Pharmacol. 2023;180:2230-2249 pubmed publisher
	Stein D, Slobodnik Z, Tam B, Einav M, Akabayov B, Berstein S, et al. 4-phenylbutyric acid-Identity crisis; can it act as a translation inhibitor?. Aging Cell. 2022;21:e13738 pubmed publisher
	Gebert M, Sobolewska A, Bartoszewska S, Cabaj A, Crossman D, Króliczewski J, et al. Genome-wide mRNA profiling identifies X-box-binding protein 1 (XBP1) as an IRE1 and PUMA repressor. Cell Mol Life Sci. 2021;78:7061-7080 pubmed publisher
	al Yacoub N, Colak D, Mahmoud S, Hammonds M, Muhammed K, Al Harazi O, et al. Mutation in FBXO32 causes dilated cardiomyopathy through up-regulation of ER-stress mediated apoptosis. Commun Biol. 2021;4:884 pubmed publisher
	Pandey R, Bakay M, Strenkowski B, Hain H, Hakonarson H. JAK/STAT inhibitor therapy partially rescues the lipodystrophic autoimmune phenotype in Clec16a KO mice. Sci Rep. 2021;11:7372 pubmed publisher
	Gonnella R, Gilardini Montani M, Guttieri L, Romeo M, Santarelli R, Cirone M. IRE1 Alpha/XBP1 Axis Sustains Primary Effusion Lymphoma Cell Survival by Promoting Cytokine Release and STAT3 Activation. Biomedicines. 2021;9: pubmed publisher
	Garufi A, Federici G, Gilardini Montani M, Crispini A, Cirone M, D Orazi G. Interplay between Endoplasmic Reticulum (ER) Stress and Autophagy Induces Mutant p53H273 Degradation. Biomolecules. 2020;10: pubmed publisher
	Ma X, Bi E, Lu Y, Su P, Huang C, Liu L, et al. Cholesterol Induces CD8+ T Cell Exhaustion in the Tumor Microenvironment. Cell Metab. 2019;: pubmed publisher
	Uchiyama T, Kawabata H, Miura Y, Yoshioka S, Iwasa M, Yao H, et al. The role of growth differentiation factor 15 in the pathogenesis of primary myelofibrosis. Cancer Med. 2015;4:1558-72 pubmed publisher
	Lee J, Fricke F, Warnken U, SchnÃ¶lzer M, Kopitz J, Gebert J. Reconstitution of TGFBR2-Mediated Signaling Causes Upregulation of GDF-15 in HCT116 Colorectal Cancer Cells. PLoS ONE. 2015;10:e0131506 pubmed publisher
	Liu X, Chi X, Gong Q, Gao L, Niu Y, Chi X, et al. Association of serum level of growth differentiation factor 15 with liver cirrhosis and hepatocellular carcinoma. PLoS ONE. 2015;10:e0127518 pubmed publisher
	Urakawa N, Utsunomiya S, Nishio M, Shigeoka M, Takase N, Arai N, et al. GDF15 derived from both tumor-associated macrophages and esophageal squamous cell carcinomas contributes to tumor progression via Akt and Erk pathways. Lab Invest. 2015;95:491-503 pubmed publisher

product information

master code :

NBP1-77681

SKU :

NBP1-77681

product name :

XBP1 Antibody - BSA Free

unit size :

0.1 ml (also 0.025 ml)

description :

The XBP1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to XBP1. This antibody reacts with human,mouse,porcine. The XBP1 Antibody - BSA Free has been validated for the following applications: Western Blot,Flow Cytometry,Chromatin Immunoprecipitation (ChIP),Knockdown Validated,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence.

target :

XBP1

category :

Primary Antibodies

buffer :

PBS

clonality :

Polyclonal

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

A genomic peptide made to an internal region of the human XBP1 protein (within residues 100-250). [Swiss-Prot P17861]

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human,Mouse,Porcine

specificity :

This antibody is specific for both XBP1s and XBP1u

gene symbol :

XBP1

accessionNumbers :

P17861, O35426

applications :

Western Blot,Flow Cytometry,Chromatin Immunoprecipitation (ChIP),Knockdown Validated,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence

USD :

409 USD

alt names :

TREB5, X-box binding protein 1, X-box-binding protein 1, XBP-1, XBP1s, XBP1u, XBP2Tax-responsive element-binding protein 5

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage