product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
PD-1 Antibody - BSA Free
catalog :
NBP1-77276
quantity :
0.1 mg (also 0.025 mg)
price :
469 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
2B7
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 14
Reference
Meng Y, Zhao Q, Sang Y, Liao J, Ye F, Qu S, et al. GPNMB+ Gal-3+ hepatic parenchymal cells promote immunosuppression and hepatocellular carcinogenesis. EMBO J. 2023;42:e114060 pubmed publisher
Xie C, You X, Zhang H, Li J, Wang L, Liu Y, et al. A Nanovaccine Based on Adjuvant Peptide FK-13 and l-Phenylalanine Poly(ester amide) Enhances CD8+ T Cell-Mediated Antitumor Immunity. Adv Sci (Weinh). 2023;10:e2300418 pubmed publisher
Sridaran D, Chouhan S, Mahajan K, Renganathan A, Weimholt C, Bhagwat S, et al. Inhibiting ACK1-mediated phosphorylation of C-terminal Src kinase counteracts prostate cancer immune checkpoint blockade resistance. Nat Commun. 2022;13:6929 pubmed publisher
Lu C, Chung W, Tsai C, Cheng J, Hsu K, Tzeng H. In vitro characterization of a small molecule PD-1 inhibitor that targets the PD-l/PD-L1 interaction. Sci Rep. 2022;12:303 pubmed publisher
Harun Or Rashid M, Pappenhagen N, Zubricky R, Coughlin L, Jassim A, Inman D. MCT2 overexpression rescues metabolic vulnerability and protects retinal ganglion cells in two models of glaucoma. Neurobiol Dis. 2020;141:104944 pubmed publisher
Agina H, Ehsan N, Abd Elaziz T, Abd Elfatah G, Said E, Sira M. Hepatic expression of programmed death-1 (PD-1) and its ligand, PD-L1, in children with autoimmune hepatitis: relation to treatment response. Clin Exp Hepatol. 2019;5:256-264 pubmed publisher
Vila I, Park M, Setijono S, Yao Y, Kim H, Badin P, et al. A muscle-specific UBE2O/AMPKα2 axis promotes insulin resistance and metabolic syndrome in obesity. JCI Insight. 2019;4: pubmed publisher
Korponay T, Balnis J, Vincent C, Singer D, Chopra A, Adam A, et al. High CO2 downregulates skeletal muscle protein anabolism via AMPKα2-mediated depressed ribosomal biogenesis. Am J Respir Cell Mol Biol. 2019;: pubmed publisher
Maeda S, Murakami K, Inoue A, Yonezawa T, Matsuki N. CCR4 Blockade Depletes Regulatory T cells and Prolongs Survival in a Canine Model of Bladder Cancer. Cancer Immunol Res. 2019;: pubmed publisher
Harun Or Rashid M, Inman D. Reduced AMPK activation and increased HCAR activation drive anti-inflammatory response and neuroprotection in glaucoma. J Neuroinflammation. 2018;15:313 pubmed publisher
Chauhan A, Liu X, Jing J, Lee H, Yadav R, Liu J, et al. STIM2 interacts with AMPK and regulates calcium-induced AMPK activation. FASEB J. 2018;:fj201801225R pubmed publisher
Dai S, Dulcey A, Hu X, Wassif C, Porter F, Austin C, et al. Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK. Autophagy. 2017;13:1435-1451 pubmed publisher
Vila I, Yao Y, Kim G, Xia W, Kim H, Kim S, et al. A UBE2O-AMPK?2 Axis that Promotes Tumor Initiation and Progression Offers Opportunities for Therapy. Cancer Cell. 2017;31:208-224 pubmed publisher
Xiao Y, Kwong M, Daemen A, Belvin M, Liang X, Hatzivassiliou G, et al. Metabolic Response to NAD Depletion across Cell Lines Is Highly Variable. PLoS ONE. 2016;11:e0164166 pubmed publisher
product information
master code :
NBP1-77276
SKU :
NBP1-77276
product name :
PD-1 Antibody - BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The PD-1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to PD-1. This antibody reacts with human,mouse,rat. The PD-1 Antibody - BSA Free has been validated for the following applications: Flow Cytometry,Immunohistochemistry,Immunocytochemistry/ Immunofluorescence,Western Blot,Immunohistochemistry-Paraffin,ELISA.
target :
PD-1
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human PD-1. The immunogen is located within amino acids 210 - 260 of PD-1.
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Rat
theoretical molecular weight :
32 kDa
gene symbol :
PDCD1
accessionNumbers :
Q15116
applications :
Flow Cytometry,Immunohistochemistry,Immunocytochemistry/ Immunofluorescence,Western Blot,Immunohistochemistry-Paraffin,ELISA
USD :
469 USD
alt names :
CD279, CD279 antigen, hPD-1, PD1hPD-l, programmed cell death 1, programmed cell death protein 1, Protein PD-1, SLEB2
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.