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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
NLRP3/NALP3 Antibody - BSA Free
catalog :
NBP1-77080
quantity :
0.1 mg (also 0.025 mg)
price :
459 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
14C8
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 99
Reference |
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Jin L, Jin F, Guo S, Liu W, Wei B, Fan H, et al. Metformin Inhibits NLR Family Pyrin Domain Containing 3 (NLRP)-Relevant Neuroinflammation via an Adenosine-5'-Monophosphate-Activated Protein Kinase (AMPK)-Dependent Pathway to Alleviate Early Brain Injury After Subarachnoid Hemorrhage in Mice. Front Pharmacol. 2022;13:796616 pubmed publisher
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López García K, E Cuevas -, Corona Quintanilla D, Jiménez Estrada I, Martinez Gomez M, Castelán F. Effect of multiparity on morphometry and oestrogen receptor expression of pelvic and perineal striated muscles in rabbits: is serum oestradiol relevant?. Eur J Obstet Gynecol Reprod Biol. 2013;169:113-20 pubmed publisher
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Sato R, Suzuki T, Katayose Y, Miura K, Shiiba K, Miki Y, et al. Aromatase in colon carcinoma. Anticancer Res. 2012;32:3069-75 pubmed
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Dohi O, Hatori M, Suzuki T, Ono K, Hosaka M, Akahira J, et al. Sex steroid receptors expression and hormone-induced cell proliferation in human osteosarcoma. Cancer Sci. 2008;99:518-23 pubmed
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Bukulmez O, Hardy D, Carr B, Word R, Mendelson C. Inflammatory status influences aromatase and steroid receptor expression in endometriosis. Endocrinology. 2008;149:1190-204 pubmed
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Caiazza F, Galluzzo P, Lorenzetti S, Marino M. 17Beta-estradiol induces ERbeta up-regulation via p38/MAPK activation in colon cancer cells. Biochem Biophys Res Commun. 2007;359:102-7 pubmed
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Gruvberger Saal S, Bendahl P, Saal L, Laakso M, Hegardt C, Edén P, et al. Estrogen receptor beta expression is associated with tamoxifen response in ERalpha-negative breast carcinoma. Clin Cancer Res. 2007;13:1987-94 pubmed
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Galluzzo P, Caiazza F, Moreno S, Marino M. Role of ERbeta palmitoylation in the inhibition of human colon cancer cell proliferation. Endocr Relat Cancer. 2007;14:153-67 pubmed
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Cvoro A, Paruthiyil S, Jones J, Tzagarakis Foster C, Clegg N, Tatomer D, et al. Selective activation of estrogen receptor-beta transcriptional pathways by an herbal extract. Endocrinology. 2007;148:538-47 pubmed
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Al Dhaheri M, Rowan B. Protein kinase A exhibits selective modulation of estradiol-dependent transcription in breast cancer cells that is associated with decreased ligand binding, altered estrogen receptor alpha promoter interaction, and changes in receptor phosphorylation. Mol Endocrinol. 2007;21:439-56 pubmed
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Skliris G, Lewis A, Emberley E, Peng B, Weebadda W, Kemp A, et al. Estrogen receptor-beta regulates psoriasin (S100A7) in human breast cancer. Breast Cancer Res Treat. 2007;104:75-85 pubmed
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Dietrich W, Haitel A, Holzer G, Huber J, Kolbus A, Tschugguel W. Estrogen receptor-beta is the predominant estrogen receptor subtype in normal human synovia. J Soc Gynecol Investig. 2006;13:512-7 pubmed
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Skliris G, Leygue E, Curtis Snell L, Watson P, Murphy L. Expression of oestrogen receptor-beta in oestrogen receptor-alpha negative human breast tumours. Br J Cancer. 2006;95:616-26 pubmed
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Savinov A, Remacle A, Golubkov V, Krajewska M, Kennedy S, Duffy M, et al. Matrix metalloproteinase 26 proteolysis of the NH2-terminal domain of the estrogen receptor beta correlates with the survival of breast cancer patients. Cancer Res. 2006;66:2716-24 pubmed
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Cvoro A, Tzagarakis Foster C, Tatomer D, Paruthiyil S, Fox M, Leitman D. Distinct roles of unliganded and liganded estrogen receptors in transcriptional repression. Mol Cell. 2006;21:555-64 pubmed
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Poola I, Fuqua S, De Witty R, Abraham J, Marshallack J, Liu A. Estrogen receptor alpha-negative breast cancer tissues express significant levels of estrogen-independent transcription factors, ERbeta1 and ERbeta5: potential molecular targets for chemoprevention. Clin Cancer Res. 2005;11:7579-85 pubmed
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Schwartz A, Prysak G, Murphy V, Lonardo F, Pass H, Schwartz J, et al. Nuclear estrogen receptor beta in lung cancer: expression and survival differences by sex. Clin Cancer Res. 2005;11:7280-7 pubmed
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Poola I, Abraham J, Baldwin K, Saunders A, Bhatnagar R. Estrogen receptors beta4 and beta5 are full length functionally distinct ERbeta isoforms: cloning from human ovary and functional characterization. Endocrine. 2005;27:227-38 pubmed
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Zheng F, Wu R, Smith C, O Malley B. Rapid estrogen-induced phosphorylation of the SRC-3 coactivator occurs in an extranuclear complex containing estrogen receptor. Mol Cell Biol. 2005;25:8273-84 pubmed
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Ishibashi H, Suzuki T, Suzuki S, Niikawa H, Lu L, Miki Y, et al. Progesterone receptor in non-small cell lung cancer--a potent prognostic factor and possible target for endocrine therapy. Cancer Res. 2005;65:6450-8 pubmed
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Helguero L, Faulds M, Gustafsson J, Haldosén L. Estrogen receptors alfa (ERalpha) and beta (ERbeta) differentially regulate proliferation and apoptosis of the normal murine mammary epithelial cell line HC11. Oncogene. 2005;24:6605-16 pubmed
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Miki Y, Suzuki T, Tazawa C, Ishizuka M, Semba S, Gorai I, et al. Analysis of gene expression induced by diethylstilbestrol (DES) in human primitive Mullerian duct cells using microarray. Cancer Lett. 2005;220:197-210 pubmed
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Jones L, Li M, Halama E, Ma Y, Lubet R, Grubbs C, et al. Promotion of mammary cancer development by tamoxifen in a mouse model of Brca1-mutation-related breast cancer. Oncogene. 2005;24:3554-62 pubmed
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Hopp T, Weiss H, Parra I, Cui Y, Osborne C, Fuqua S. Low levels of estrogen receptor beta protein predict resistance to tamoxifen therapy in breast cancer. Clin Cancer Res. 2004;10:7490-9 pubmed
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Balfe P, McCann A, McGoldrick A, McAllister K, Kennedy M, Dervan P, et al. Estrogen receptor alpha and beta profiling in human breast cancer. Eur J Surg Oncol. 2004;30:469-74 pubmed
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Speirs V, Carder P, Lane S, Dodwell D, Lansdown M, Hanby A. Oestrogen receptor beta: what it means for patients with breast cancer. Lancet Oncol. 2004;5:174-81 pubmed
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Paruthiyil S, Parmar H, Kerekatte V, Cunha G, Firestone G, Leitman D. Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest. Cancer Res. 2004;64:423-8 pubmed
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Tee M, Rogatsky I, Tzagarakis Foster C, Cvoro A, An J, Christy R, et al. Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta. Mol Biol Cell. 2004;15:1262-72 pubmed
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Tonetti D, Rubenstein R, DeLeon M, Zhao H, Pappas S, Bentrem D, et al. Stable transfection of an estrogen receptor beta cDNA isoform into MDA-MB-231 breast cancer cells. J Steroid Biochem Mol Biol. 2003;87:47-55 pubmed
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Skliris G, Munot K, Bell S, Carder P, Lane S, Horgan K, et al. Reduced expression of oestrogen receptor beta in invasive breast cancer and its re-expression using DNA methyl transferase inhibitors in a cell line model. J Pathol. 2003;201:213-20 pubmed
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Li X, Hisaoka M, Hashimoto H. Expression of estrogen receptors alpha and beta in soft tissue sarcomas: Immunohistochemical and molecular analysis. Pathol Int. 2003;53:671-9 pubmed
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Omoto Y, Eguchi H, Yamamoto Yamaguchi Y, Hayashi S. Estrogen receptor (ER) beta1 and ERbetacx/beta2 inhibit ERalpha function differently in breast cancer cell line MCF7. Oncogene. 2003;22:5011-20 pubmed
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Fuqua S, Schiff R, Parra I, Moore J, Mohsin S, Osborne C, et al. Estrogen receptor beta protein in human breast cancer: correlation with clinical tumor parameters. Cancer Res. 2003;63:2434-9 pubmed
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Linja M, Savinainen K, Tammela T, Isola J, Visakorpi T. Expression of ERalpha and ERbeta in prostate cancer. Prostate. 2003;55:180-6 pubmed
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Saji S, Omoto Y, Shimizu C, Warner M, Hayashi Y, Horiguchi S, et al. Expression of estrogen receptor (ER) (beta)cx protein in ER(alpha)-positive breast cancer: specific correlation with progesterone receptor. Cancer Res. 2002;62:4849-53 pubmed
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Skliris G, Parkes A, Limer J, Burdall S, Carder P, Speirs V. Evaluation of seven oestrogen receptor beta antibodies for immunohistochemistry, western blotting, and flow cytometry in human breast tissue. J Pathol. 2002;197:155-62 pubmed
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Speirs V, Skliris G, Burdall S, Carder P. Distinct expression patterns of ER alpha and ER beta in normal human mammary gland. J Clin Pathol. 2002;55:371-4 pubmed
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Skliris G, Carder P, Lansdown M, Speirs V. Immunohistochemical detection of ERbeta in breast cancer: towards more detailed receptor profiling?. Br J Cancer. 2001;84:1095-8 pubmed
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product information
master code :
NBP1-77080
SKU :
NBP1-77080
product name :
NLRP3/NALP3 Antibody - BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The NLRP3/NALP3 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to NLRP3/NALP3. This antibody reacts with bacteria - escherichia coli,e. coli,human,mouse. The NLRP3/NALP3 Antibody - BSA Free has been validated for the following applications: IF/IHC,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,SDS-Page,Immunocytochemistry/ Immunofluorescence,ELISA,Immunohistochemistry.
target :
NLRP3/NALP3
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
NLRP3/NALP3 Antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human NALP3. The immunogen is located within amino acids 120 - 170 of NALP3.
isotype :
IgG
purity :
Immunogen affinity purified
species :
Bacteria - Escherichia coli,E. coli,Human,Mouse
theoretical molecular weight :
110 kDa
gene symbol :
NLRP3
Antibody validation :
Biological Validation
accessionNumbers :
Q96P20
applications :
IF/IHC,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,SDS-Page,Immunocytochemistry/ Immunofluorescence,ELISA,Immunohistochemistry
USD :
459 USD
alt names :
AII, AII/AVP, Angiotensin/vasopressin receptor AII/AVP-like, AVP, C1orf7, Caterpiller protein 1.1, CLR1.1, Cold autoinflammatory syndrome 1, Cold autoinflammatory syndrome 1 protein, Cryopyrin, Familial cold autoinflammatory syndrome, FCU, Leucine-rich repeat-, and PYD-containing protein 3, Muckle-Wells syndrome, MWS, NACHT, LRR and PYD containing protein 3, NACHT, LRR and PYD domains-containing protein 3, NALP3, NLR family, pyrin domain containing 3, NLRP3, Nucleotide-Binding Oligomerization Domain, Leucine Rich Repeat And Pyrin Domain Containing 3, PYPAF1, PYRIN-containing APAF1-like protein 1
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information

Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.
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