product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
RIPK1/RIP1 Antibody - BSA Free
catalog :
NBP1-77077
quantity :
0.1 mg (also 0.025 mg)
price :
449 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry knockout validation
more info or order :
citations: 25
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry knockout validation; mouse; 1:100; loading ...; fig s1c, s1d
Wehn A, Khalin I, Duering M, Hellal F, Culmsee C, Vandenabeele P, et al. RIPK1 or RIPK3 deletion prevents progressive neuronal cell death and improves memory function after traumatic brain injury. Acta Neuropathol Commun. 2021;9:138 pubmed publisher
  • immunocytochemistry; human; loading ...; fig s6b
  • immunohistochemistry; human; loading ...; fig 1c
  • western blot; human; 1:1000; loading ...; fig 1d
Al Lamki R, Lu W, Manalo P, Wang J, Warren A, Tolkovsky A, et al. Tubular epithelial cells in renal clear cell carcinoma express high RIPK1/3 and show increased susceptibility to TNF receptor 1-induced necroptosis. Cell Death Dis. 2016;7:e2287 pubmed publisher
Miyake K, Ito J, Takahashi K, Nakabayashi J, Brombacher F, Shichino S, et al. Single-cell transcriptomics identifies the differentiation trajectory from inflammatory monocytes to pro-resolving macrophages in a mouse skin allergy model. Nat Commun. 2024;15:1666 pubmed publisher
Chen X, Huang L, Tang J, Wu D, An N, Ye Z, et al. Asiatic acid alleviates cisplatin-induced renal fibrosis in tumor-bearing mice by improving the TFEB-mediated autophagy-lysosome pathway. Biomed Pharmacother. 2023;165:115122 pubmed publisher
Shao R, Xie Q, Pan L, Lin F, Qin K, Ming S, et al. Necrostatin-1 attenuates Caspase-1-dependent pyroptosis induced by the RIPK1/ZBP1 pathway in ventilator-induced lung injury. Cytokine. 2022;157:155950 pubmed publisher
Liu K, Huang J, Liu J, Klionsky D, Kang R, Tang D. Induction of autophagy-dependent ferroptosis to eliminate drug-tolerant human retinoblastoma cells. Cell Death Dis. 2022;13:521 pubmed publisher
Nicol xe8 L, Sanavia T, Cappellesso R, Maffeis V, Akiba J, Kawahara A, et al. Necroptosis-driving genes RIPK1, RIPK3 and MLKL-p are associated with intratumoral CD3+ and CD8+ T cell density and predict prognosis in hepatocellular carcinoma. J Immunother Cancer. 2022;10: pubmed publisher
Kamiya M, Mizoguchi F, Kawahata K, Wang D, Nishibori M, Day J, et al. Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies. Nat Commun. 2022;13:166 pubmed publisher
Pesce N, Canovai A, Plastino F, Lardner E, Kvanta A, Cammalleri M, et al. An imbalance in autophagy contributes to retinal damage in a rat model of oxygen-induced retinopathy. J Cell Mol Med. 2021;25:10480-10493 pubmed publisher
Thadathil N, Nicklas E, Mohammed S, Lewis T, Richardson A, Deepa S. Necroptosis increases with age in the brain and contributes to age-related neuroinflammation. GeroScience. 2021;43:2345-2361 pubmed publisher
Naseroleslami M, Niri N, Akbarzade I, Sharifi M, Aboutaleb N. Simvastatin-loaded nano-niosomes confer cardioprotection against myocardial ischemia/reperfusion injury. Drug Deliv Transl Res. 2021;: pubmed publisher
Sharifi M, Nazarinia D, Ramezani F, Azizi Y, Naderi N, Aboutaleb N. Necroptosis and RhoA/ROCK pathways: molecular targets of Nesfatin-1 in cardioprotection against myocardial ischemia/reperfusion injury in a rat model. Mol Biol Rep. 2021;48:2507-2518 pubmed publisher
Zhao Y, Zhu X, Zhang L, Ferguson C, Song T, Jiang K, et al. Mesenchymal Stem/Stromal Cells and their Extracellular Vesicle Progeny Decrease Injury in Poststenotic Swine Kidney Through Different Mechanisms. Stem Cells Dev. 2020;29:1190-1200 pubmed publisher
Alhakamy N, Md S. Repurposing Itraconazole Loaded PLGA Nanoparticles for Improved Antitumor Efficacy in Non-Small Cell Lung Cancers. Pharmaceutics. 2019;11: pubmed publisher
Li J, Shi J, Pan Y, Zhao Y, Yan F, Li H, et al. Transcription modulation by CDK9 regulates inflammatory genes and RIPK3-MLKL-mediated necroptosis in periodontitis progression. Sci Rep. 2019;9:17369 pubmed publisher
Du X, Ge W, Jing R, Pan L. Necroptosis in pulmonary macrophages mediates lipopolysaccharide-induced lung inflammatory injury by activating ZBP-1. Int Immunopharmacol. 2019;77:105944 pubmed publisher
Bao Z, Fan L, Zhao L, Xu X, Liu Y, Chao H, et al. Silencing of A20 Aggravates Neuronal Death and Inflammation After Traumatic Brain Injury: A Potential Trigger of Necroptosis. Front Mol Neurosci. 2019;12:222 pubmed publisher
Wu Z, Fournel L, Stadler N, Liu J, Boullier A, Hoyeau N, et al. Modulation of lung cancer cell plasticity and heterogeneity with the restoration of cisplatin sensitivity by neurotensin antibody. Cancer Lett. 2019;444:147-161 pubmed publisher
Moon S, Choi H, Chung T, Lee J, Lee S, Jung M, et al. Sorbus commixta water extract induces apoptotic cell death via a ROS-dependent pathway. Oncol Lett. 2018;16:4193-4200 pubmed publisher
Ghardashi Afousi A, Gaeini A, Rakhshan K, Naderi N, Darbandi Azar A, Aboutaleb N. Targeting necroptotic cell death pathway by high-intensity interval training (HIIT) decreases development of post-ischemic adverse remodelling after myocardial ischemia / reperfusion injury. J Cell Commun Signal. 2019;13:255-267 pubmed publisher
Tsuiji H, Inoue I, Takeuchi M, Furuya A, Yamakage Y, Watanabe S, et al. TDP-43 accelerates age-dependent degeneration of interneurons. Sci Rep. 2017;7:14972 pubmed publisher
Lin J, Chen C, Yang H, Chen Y, Hung S. Electroacupuncture Promotes Recovery of Motor Function and Reduces Dopaminergic Neuron Degeneration in Rodent Models of Parkinson's Disease. Int J Mol Sci. 2017;18: pubmed publisher
Huang X, Huang R, Gou S, Wang Z, Liao Z, Wang H. Combretastatin A-4 Analogue: A Dual-Targeting and Tubulin Inhibitor Containing Antitumor Pt(IV) Moiety with a Unique Mode of Action. Bioconjug Chem. 2016;27:2132-48 pubmed publisher
Chopra D, Ray L, Dwivedi A, Tiwari S, Singh J, Singh K, et al. Photoprotective efficiency of PLGA-curcumin nanoparticles versus curcumin through the involvement of ERK/AKT pathway under ambient UV-R exposure in HaCaT cell line. Biomaterials. 2016;84:25-41 pubmed publisher
Miki Y, Akimoto J, Moritake K, Hironaka C, Fujiwara Y. Photodynamic therapy using talaporfin sodium induces concentration-dependent programmed necroptosis in human glioblastoma T98G cells. Lasers Med Sci. 2015;30:1739-45 pubmed publisher
product information
master code :
NBP1-77077
SKU :
NBP1-77077
product name :
RIPK1/RIP1 Antibody - BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The RIPK1/RIP1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to RIPK1/RIP1. This antibody reacts with human,mouse,rat. The RIPK1/RIP1 Antibody - BSA Free has been validated for the following applications: Immunohistochemistry-Paraffin,IF/IHC,Immunohistochemistry,Western Blot,Knockdown Validated,Immunocytochemistry/ Immunofluorescence,ELISA.
target :
RIPK1/RIP1
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human RIPK1. The immunogen is located within amino acids 180 - 230 of RIPK1. Amino Acid Squence: DVNAKPTEKSDVYS
isotype :
IgG
purity :
Peptide affinity purified
species :
Human,Mouse,Rat
theoretical molecular weight :
70.7 kDa
gene symbol :
RIPK1
Antibody validation :
Biological Validation
accessionNumbers :
Q13546
applications :
IF/IHC,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Knockdown Validated,Immunocytochemistry/ Immunofluorescence,ELISA
USD :
449 USD
alt names :
Cell death protein RIP, EC 2.7.11.1, receptor (TNFRSF)-interacting serine-threonine kinase 1, receptor interacting protein, Receptor-interacting protein 1, receptor-interacting serine/threonine-protein kinase 1, RIP1, RIP-1, Rip1 kinase, RIPFLJ39204, Serine/threonine-protein kinase RIP
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.