product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
TREX1 Antibody - BSA Free
catalog :
NBP1-76977
quantity :
0.1 mg (also 0.025 mg)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
BXP-21
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 8
Reference
Hussein N, Ashby C, Amawi H, Nyinawabera A, Vij A, Khare V, et al. Cariprazine, A Dopamine D?/D? Receptor Partial Agonist, Modulates ABCG2-Mediated Multidrug Resistance in Cancer. Cancers (Basel). 2018;10: pubmed publisher
Hammad A, Alasmari F, Sari Y, Scott Hall F, Tiwari A. Alcohol and Cocaine Exposure Modulates ABCB1 and ABCG2 Transporters in Male Alcohol-Preferring Rats. Mol Neurobiol. 2019;56:1921-1932 pubmed publisher
Takahashi A, Loo T, Okada R, Kamachi F, Watanabe Y, Wakita M, et al. Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells. Nat Commun. 2018;9:1249 pubmed publisher
Hussein N, Amawi H, Karthikeyan C, Hall F, Mittal R, Trivedi P, et al. The dopamine D3 receptor antagonists PG01037, NGB2904, SB277011A, and U99194 reverse ABCG2 transporter-mediated drug resistance in cancer cell lines. Cancer Lett. 2017;396:167-180 pubmed publisher
Liang S, Yang C, Tseng J, Wang H, Tung C, Liu H, et al. ABCG2 localizes to the nucleus and modulates CDH1 expression in lung cancer cells. Neoplasia. 2015;17:265-78 pubmed publisher
Venkatraman G, Benesch M, Tang X, Dewald J, McMullen T, Brindley D. Lysophosphatidate signaling stabilizes Nrf2 and increases the expression of genes involved in drug resistance and oxidative stress responses: implications for cancer treatment. FASEB J. 2015;29:772-85 pubmed publisher
Svirnovski A, Shman T, Serhiyenka T, Savitski V, Smolnikova V, Fedasenka U. ABCB1 and ABCG2 proteins, their functional activity and gene expression in concert with drug sensitivity of leukemia cells. Hematology. 2009;14:204-12 pubmed publisher
Ejendal K, Diop N, Schweiger L, Hrycyna C. The nature of amino acid 482 of human ABCG2 affects substrate transport and ATP hydrolysis but not substrate binding. Protein Sci. 2006;15:1597-607 pubmed
product information
master code :
NBP1-76977
SKU :
NBP1-76977
product name :
TREX1 Antibody - BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The TREX1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to TREX1. This antibody reacts with human,mouse,rat. The TREX1 Antibody - BSA Free has been validated for the following applications: Immunocytochemistry/ Immunofluorescence,ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin.
target :
TREX1
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Antibody was raised against a 15 amino acid synthetic peptide near the center of human TREX1. The immunogen is located within amino acids 220 - 270 of TREX1. Amino Acid Squence: TRLYGQSPPDSHT
isotype :
IgG
purity :
Peptide affinity purified
species :
Human,Mouse,Rat
specificity :
TREX1 antibody will not cross-react with the related protein TREX2
theoretical molecular weight :
31 kDa
gene symbol :
TREX1
accessionNumbers :
NP_057465
applications :
Immunocytochemistry/ Immunofluorescence,ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin
USD :
409 USD
alt names :
3'-5' exonuclease TREX1, AGS1, Aicardi-Goutieres syndrome 1, CRV, DKFZp434J0310, DNase III, DRN3, EC 3.1.11.2, HERNS, three prime repair exonuclease 1,3' repair exonuclease 1
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.