product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Caspase-12 Antibody - BSA Free
catalog :
NBP1-76801
quantity :
0.1 mg (also 0.025 mg)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
1D9
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 14
Reference
Kulesskaya N, Bhattacharjee A, Holmstr xf6 m K, Vuorio P, Henriques A, Callizot N, et al. HER-096 is a CDNF-derived brain-penetrating peptidomimetic that protects dopaminergic neurons in a mouse synucleinopathy model of Parkinson's disease. Cell Chem Biol. 2024;31:593-606.e9 pubmed publisher
Chen J, Zhou Y, Zhu E, Yang P, Li M, Zhang S, et al. Mycoplasma ovipneumoniae induces caspase-8-dependent extrinsic apoptosis and p53- and ROS-dependent intrinsic apoptosis in murine alveolar macrophages. Virulence. 2021;12:2703-2720 pubmed publisher
Wang H, Dou S, Zhu J, Shao Z, Wang C, Cheng B. Ghrelin protects dopaminergic neurons against MPTP neurotoxicity through promoting autophagy and inhibiting endoplasmic reticulum mediated apoptosis. Brain Res. 2020;1746:147023 pubmed publisher
Yao J, Ma Y, Lin X, Zhou S, Mi Y, Zhang C. The Attenuating Effect of the Intraovarian Bone Morphogenetic Protein 4 on Age-Related Endoplasmic Reticulum Stress in Chicken Follicular Cells. Oxid Med Cell Longev. 2020;2020:4175613 pubmed publisher
Wei M, Zhu Z, Wu J, Wang Y, Geng J, Qin Z. DRAM1 deficiency affects the organization and function of the Golgi apparatus. Cell Signal. 2019;63:109375 pubmed publisher
Jang Y, Kwon I, Song W, Cosio Lima L, Taylor S, Lee Y. Modulation of mitochondrial phenotypes by endurance exercise contributes to neuroprotection against a MPTP-induced animal model of PD. Life Sci. 2018;209:455-465 pubmed publisher
Ramírez Peinado S, Ignashkova T, van Raam B, Baumann J, Sennott E, Gendarme M, et al. TRAPPC13 modulates autophagy and the response to Golgi stress. J Cell Sci. 2017;130:2251-2265 pubmed publisher
Reiling J, Olive A, Sanyal S, Carette J, Brummelkamp T, Ploegh H, et al. A CREB3-ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens. Nat Cell Biol. 2013;15:1473-85 pubmed publisher
Wang J, Sun H, Macia E, Kirchhausen T, Watson H, Bonifacino J, et al. PI4P promotes the recruitment of the GGA adaptor proteins to the trans-Golgi network and regulates their recognition of the ubiquitin sorting signal. Mol Biol Cell. 2007;18:2646-55 pubmed
Shen X, Xu K, Fan Q, Pacheco Rodriguez G, Moss J, Vaughan M. Association of brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BIG2) with recycling endosomes during transferrin uptake. Proc Natl Acad Sci U S A. 2006;103:2635-40 pubmed
Belov G, Fogg M, Ehrenfeld E. Poliovirus proteins induce membrane association of GTPase ADP-ribosylation factor. J Virol. 2005;79:7207-16 pubmed
Chan D, Strang M, Judson B, Brown W. Inhibition of membrane tubule formation and trafficking by isotetrandrine, an antagonist of G-protein-regulated phospholipase A2 enzymes. Mol Biol Cell. 2004;15:1871-80 pubmed
Spitzenberger F, Pietropaolo S, Verkade P, Habermann B, Lacas Gervais S, Mziaut H, et al. Islet cell autoantigen of 69 kDa is an arfaptin-related protein associated with the Golgi complex of insulinoma INS-1 cells. J Biol Chem. 2003;278:26166-73 pubmed
Lu L, Horstmann H, Ng C, Hong W. Regulation of Golgi structure and function by ARF-like protein 1 (Arl1). J Cell Sci. 2001;114:4543-55 pubmed
product information
master code :
NBP1-76801
SKU :
NBP1-76801
product name :
Caspase-12 Antibody - BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The Caspase-12 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to Caspase-12. This antibody reacts with avian - chicken,chicken,human,mouse,rat. The Caspase-12 Antibody - BSA Free has been validated for the following applications: Western Blot,Immunocytochemistry/ Immunofluorescence,ELISA,Immunohistochemistry,Immunohistochemistry-Paraffin.
target :
Caspase-12
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Antibody was raised against a 17 amino acid peptide near the center of murine Caspase-12. The immunogen is located within amino acids 90 - 140 of Caspase-12. Amino Acid Squence: CTPSSPSESKRKVEDDE
isotype :
IgG
purity :
Peptide affinity purified
species :
Avian - Chicken,Chicken,Human,Mouse,Rat
theoretical molecular weight :
55 kDa
gene symbol :
CASP12
accessionNumbers :
CAA73532
applications :
Western Blot,Immunocytochemistry/ Immunofluorescence,ELISA,Immunohistochemistry,Immunohistochemistry-Paraffin
USD :
409 USD
alt names :
Apoptosis Related Cysteine Protease, CASP 12, casp12, CASP12P1, Caspase 12 pseudogene 1, Caspase12, UNQ9415
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.