product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
PD-L2/B7-DC/PDCD1LG2 Antibody - BSA Free
catalog :
NBP1-76770
quantity :
0.1 mg (also 0.025 mg)
price :
459 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
B2
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 10
Reference
Guo H, Zhang C, Shen Y, Zhang J, Yang F, Liang F, et al. PD-L2 mediates tobacco smoking-induced recruitment of regulatory T cells via the RGMB/NFκB/CCL20 cascade. Cell Biol Toxicol. 2024;40:56 pubmed publisher
Navneet S, Zhao J, Wang J, Mysona B, Barwick S, Ammal Kaidery N, et al. Hyperhomocysteinemia-induced death of retinal ganglion cells: The role of Müller glial cells and NRF2. Redox Biol. 2019;24:101199 pubmed publisher
Navneet S, Cui X, Zhao J, Wang J, Kaidery N, Thomas B, et al. Excess homocysteine upregulates the NRF2-antioxidant pathway in retinal Müller glial cells. Exp Eye Res. 2019;178:228-237 pubmed publisher
Golestaneh N, Chu Y, Xiao Y, Stoleru G, Theos A. Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration. Cell Death Dis. 2017;8:e2537 pubmed publisher
Biesecker K, Srienc A, Shimoda A, Agarwal A, Bergles D, Kofuji P, et al. Glial Cell Calcium Signaling Mediates Capillary Regulation of Blood Flow in the Retina. J Neurosci. 2016;36:9435-45 pubmed publisher
Heller J, Kwok J, Vecino E, Martin K, Fawcett J. A Method for the Isolation and Culture of Adult Rat Retinal Pigment Epithelial (RPE) Cells to Study Retinal Diseases. Front Cell Neurosci. 2015;9:449 pubmed publisher
Unterlauft J, Eichler W, Kuhne K, Yang X, Yafai Y, Wiedemann P, et al. Pigment epithelium-derived factor released by Müller glial cells exerts neuroprotective effects on retinal ganglion cells. Neurochem Res. 2012;37:1524-33 pubmed publisher
Arnold T, Ferrero G, Qiu H, Phan I, Akhurst R, Huang E, et al. Defective retinal vascular endothelial cell development as a consequence of impaired integrin ?V?8-mediated activation of transforming growth factor-?. J Neurosci. 2012;32:1197-206 pubmed publisher
Lu B, Malcuit C, Wang S, Girman S, Francis P, Lemieux L, et al. Long-term safety and function of RPE from human embryonic stem cells in preclinical models of macular degeneration. Stem Cells. 2009;27:2126-35 pubmed publisher
Budhu A, Noy N. Direct channeling of retinoic acid between cellular retinoic acid-binding protein II and retinoic acid receptor sensitizes mammary carcinoma cells to retinoic acid-induced growth arrest. Mol Cell Biol. 2002;22:2632-41 pubmed
product information
master code :
NBP1-76770
SKU :
NBP1-76770
product name :
PD-L2/B7-DC/PDCD1LG2 Antibody - BSA Free
unit size :
0.1 mg (also 0.025 mg)
description :
The PD-L2/B7-DC/PDCD1LG2 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to PD-L2/B7-DC/PDCD1LG2. This antibody reacts with human,mouse. The PD-L2/B7-DC/PDCD1LG2 Antibody - BSA Free has been validated for the following applications: ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunofluorescence,Immunocytochemistry/ Immunofluorescence.
target :
PD-L2/B7-DC/PDCD1LG2
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Antibody was raised against a peptide corresponding to 16 amino acids near the center of human PD-L2/B7-DC/PDCD1LG2. The immunogen is located within amino acids 140-190 of PD-L2/B7-DC/PDCD1LG2. Amino Acid Sequence: SVPANTSHSRTPEGLY
isotype :
IgG
purity :
Peptide affinity purified
species :
Human,Mouse
specificity :
Human PD-L2/B7-DC/PDCD1LG2 has 3 isoforms, including isoform 1 (273aa, 31kD), isoform 2 (183aa, 21kD) and isoform 3 (182aa, 21kD)
theoretical molecular weight :
29 kDa
gene symbol :
PDCD1LG2
Antibody validation :
Independent Anitbodies
accessionNumbers :
NP_079515
applications :
ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunofluorescence,Immunocytochemistry/ Immunofluorescence
USD :
459 USD
alt names :
B7-DC, bA574F11.2, Btdc, Butyrophilin B7-DC, CD273 antigen, CD273PD-1 ligand 2, MGC142240, PD-1-ligand 2, PDCD1L2MGC142238, PDL2B7DC, PD-L2PDCD1 ligand 2, programmed cell death 1 ligand 2, Programmed death ligand 2
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.