product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Mitofusin 1 Antibody (11E9-1H12) - BSA Free
catalog :
NBP1-71775
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
11E9-1H12
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 30
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:500; loading ...; fig 7b
Li T, Li K, Zhang S, Wang Y, Xu Y, Cronin S, et al. Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice. Cell Death Dis. 2020;11:77 pubmed publisher
  • western blot; human
Montaigne D, Marechal X, Coisne A, Debry N, Modine T, Fayad G, et al. Myocardial contractile dysfunction is associated with impaired mitochondrial function and dynamics in type 2 diabetic but not in obese patients. Circulation. 2014;130:554-64 pubmed publisher
  • western blot; human
Wu Z, Zhu Y, Cao X, Sun S, Zhao B. Mitochondrial toxic effects of A? through mitofusins in the early pathogenesis of Alzheimer's disease. Mol Neurobiol. 2014;50:986-96 pubmed publisher
  • western blot; rat
Amadoro G, Corsetti V, Florenzano F, Atlante A, Ciotti M, Mongiardi M, et al. AD-linked, toxic NH2 human tau affects the quality control of mitochondria in neurons. Neurobiol Dis. 2014;62:489-507 pubmed publisher
  • western blot; rat
Wappler E, Institoris A, Dutta S, Katakam P, Busija D. Mitochondrial dynamics associated with oxygen-glucose deprivation in rat primary neuronal cultures. PLoS ONE. 2013;8:e63206 pubmed publisher
  • western blot; mouse
White J, Puppa M, Sato S, Gao S, Price R, Baynes J, et al. IL-6 regulation on skeletal muscle mitochondrial remodeling during cancer cachexia in the ApcMin/+ mouse. Skelet Muscle. 2012;2:14 pubmed publisher
  • western blot; mouse
Trushina E, Nemutlu E, Zhang S, Christensen T, Camp J, Mesa J, et al. Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease. PLoS ONE. 2012;7:e32737 pubmed publisher
  • western blot; mouse
Xu Y, Gendron T, Zhang Y, Lin W, D Alton S, Sheng H, et al. Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice. J Neurosci. 2010;30:10851-9 pubmed publisher
Jin Y, Kim T, Kim T. Effect of Physical Exercise on Mitochondrial Dysfunction and Purkinje Cell Survival in the Cerebellum of 3xTg-AD Mice. J Integr Neurosci. 2023;22:117 pubmed publisher
Kawalec M, Wojtyniak P, Bielska E, Lewczuk A, Boraty x144 ska Jasi x144 ska A, Ber x119 sewicz Haller M, et al. Mitochondrial dynamics, elimination and biogenesis during post-ischemic recovery in ischemia-resistant and ischemia-vulnerable gerbil hippocampal regions. Biochim Biophys Acta Mol Basis Dis. 2023;1869:166633 pubmed publisher
Wojtyniak P, Boratyńska Jasińska A, Serwach K, Gruszczynska Biegala J, Zablocka B, Jaworski J, et al. Mitofusin 2 Integrates Mitochondrial Network Remodelling, Mitophagy and Renewal of Respiratory Chain Proteins in Neurons after Oxygen and Glucose Deprivation. Mol Neurobiol. 2022;59:6502-6518 pubmed publisher
Bhatia D, Capili A, Nakahira K, Muthukumar T, Torres L, Choi A, et al. Conditional deletion of myeloid-specific mitofusin 2 but not mitofusin 1 promotes kidney fibrosis. Kidney Int. 2022;101:963-986 pubmed publisher
Peng G, Zheng H, Wu C, Wu C, Ma X, Xiong J, et al. Intranasal administration of DHED protects against exhaustive exercise-induced brain injury in rats. Brain Res. 2021;1772:147665 pubmed publisher
Halder A, Yadav K, Aggarwal A, Singhal N, Sandhir R. Activation of TNFR1 and TLR4 following oxygen glucose deprivation promotes mitochondrial fission in C6 astroglial cells. Cell Signal. 2020;75:109714 pubmed publisher
Zhang X, Zhao D, Wu W, Ali Shah S, Lai M, Yang D, et al. Melatonin regulates mitochondrial dynamics and alleviates neuron damage in prion diseases. Aging (Albany NY). 2020;12:11139-11151 pubmed publisher
Pandey K, Yu X, Steinmetz A, Alberini C. Autophagy coupled to translation is required for long-term memory. Autophagy. 2020;: pubmed publisher
Saha P, Shumate J, Caldwell J, Elghobashi Meinhardt N, Lu A, Zhang L, et al. Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins. elife. 2020;9: pubmed publisher
Kim D, Cho J, Kang H. Protective effect of exercise training against the progression of Alzheimer's disease in 3xTg-AD mice. Behav Brain Res. 2019;374:112105 pubmed publisher
Bahat A, Goldman A, Zaltsman Y, Khan D, Halperin C, Amzallag E, et al. MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells. Nat Commun. 2018;9:5132 pubmed publisher
Mittal E, Skowyra M, Uwase G, Tinaztepe E, Mehra A, Köster S, et al. Mycobacterium tuberculosis Type VII Secretion System Effectors Differentially Impact the ESCRT Endomembrane Damage Response. MBio. 2018;9: pubmed publisher
Xie W, Zheng W, Liu M, Qin Q, Zhao Y, Cheng Z, et al. BRF1 ameliorates LPS-induced inflammation through autophagy crosstalking with MAPK/ERK signaling. Genes Dis. 2018;5:226-234 pubmed publisher
Nobis S, Goichon A, Achamrah N, Guérin C, Azhar S, Chan P, et al. Alterations of proteome, mitochondrial dynamic and autophagy in the hypothalamus during activity-based anorexia. Sci Rep. 2018;8:7233 pubmed publisher
Kevadiya B, Woldstad C, Ottemann B, Dash P, Sajja B, Lamberty B, et al. Multimodal Theranostic Nanoformulations Permit Magnetic Resonance Bioimaging of Antiretroviral Drug Particle Tissue-Cell Biodistribution. Theranostics. 2018;8:256-276 pubmed publisher
Köster S, Upadhyay S, Chandra P, Papavinasasundaram K, Yang G, Hassan A, et al. Mycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA. Proc Natl Acad Sci U S A. 2017;114:E8711-E8720 pubmed publisher
Ahmed N, Yang P, Huang Y, Chen H, Liu T, Wang L, et al. Entosis Acts as a Novel Way within Sertoli Cells to Eliminate Spermatozoa in Seminiferous Tubule. Front Physiol. 2017;8:361 pubmed publisher
Gouwens L, Makoni N, Rogers V, Nichols M. Amyloid-?42 protofibrils are internalized by microglia more extensively than monomers. Brain Res. 2016;1648:485-495 pubmed publisher
Sidjanin D, Park A, Ronchetti A, Martins J, Jackson W. TBC1D20 mediates autophagy as a key regulator of autophagosome maturation. Autophagy. 2016;12:1759-1775 pubmed
Rodriguez M, Kaushik A, Lapierre J, Dever S, El Hage N, Nair M. Electro-Magnetic Nano-Particle Bound Beclin1 siRNA Crosses the Blood-Brain Barrier to Attenuate the Inflammatory Effects of HIV-1 Infection in Vitro. J Neuroimmune Pharmacol. 2017;12:120-132 pubmed publisher
Dever S, Rodriguez M, Lapierre J, COSTIN B, El Hage N. Differing roles of autophagy in HIV-associated neurocognitive impairment and encephalitis with implications for morphine co-exposure. Front Microbiol. 2015;6:653 pubmed publisher
Khatter D, Raina V, Dwivedi D, Sindhwani A, Bahl S, Sharma M. The small GTPase Arl8b regulates assembly of the mammalian HOPS complex on lysosomes. J Cell Sci. 2015;128:1746-61 pubmed publisher
product information
master code :
NBP1-71775
SKU :
NBP1-71775
product name :
Mitofusin 1 Antibody (11E9-1H12) - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The Mitofusin 1 Antibody (11E9-1H12) - BSA Free from Novus is a mouse monoclonal antibody to Mitofusin 1. This antibody reacts with gerbil,human,mouse,rat. The Mitofusin 1 Antibody (11E9-1H12) - BSA Free has been validated for the following applications: IF/IHC,Flow Cytometry,Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin,Knockout Validated.
target :
Mitofusin 1
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
11E9-1H12
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse Mitofusin 1 [Swiss-Prot: Q811U4]
isotype :
IgG2b Kappa
purity :
Protein G purified
species :
Gerbil,Human,Mouse,Rat
theoretical molecular weight :
80 kDa
gene symbol :
MFN1
Antibody validation :
Knockout/Knockdown
applications :
IF/IHC,Flow Cytometry,Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin,Knockout Validated
USD :
409 USD
alt names :
DKFZp762F247, EC 3.6.5, EC 3.6.5.-, FLJ20693, Fzo homolog, hfzo1, hfzo2, MGC41806, mitochondrial transmembrane GTPase Fzo-1, mitochondrial transmembrane GTPase FZO-2, mitofusin 1, mitofusin-1, putative transmembrane GTPase, Transmembrane GTPase MFN1
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.