PAR1/Thrombin Receptor Antibody (N2-11) - BSA Free | Novus Biologicals NBP1-71770 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

PAR1/Thrombin Receptor Antibody (N2-11) - BSA Free

catalog :

NBP1-71770

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

N2-11

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 22

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse	Gonda K, Watanabe T, Ohuchi N, Higuchi H. In vivo nano-imaging of membrane dynamics in metastatic tumor cells using quantum dots. J Biol Chem. 2010;285:2750-7 pubmed publisher
	Hwang Y, Cho H, Park E, Lim J, Yoon H, Kim J, et al. KLK6/PAR1 Axis Promotes Tumor Growth and Metastasis by Regulating Cross-Talk between Tumor Cells and Macrophages. Cells. 2022;11: pubmed publisher
	Hayashi Y, Shimizu I, Yoshida Y, Ikegami R, Suda M, Katsuumi G, et al. Coagulation factors promote brown adipose tissue dysfunction and abnormal systemic metabolism in obesity. iScience. 2022;25:104547 pubmed publisher
	Goldberg Z, Sher I, Qassim L, Chapman J, Rotenstreich Y, Shavit Stein E. Intrinsic Expression of Coagulation Factors and Protease Activated Receptor 1 (PAR1) in Photoreceptors and Inner Retinal Layers. Int J Mol Sci. 2022;23: pubmed publisher
	Chen R, Cao X, Luo W, Yang H, Luo X, Yu J, et al. Dabigatran Suppresses PAR-1/SphK/S1P Activation of Astrocytes in Experimental Autoimmune Encephalomyelitis Model. Front Mol Neurosci. 2020;13:114 pubmed publisher
	Hurley Novatny A, Arumugasaamy N, Kimicata M, Baker H, Mikos A, Fisher J. Concurrent multi-lineage differentiation of mesenchymal stem cells through spatial presentation of growth factors. Biomed Mater. 2020;15:055035 pubmed publisher
	Nishimura F, Mogami H, Moriuchi K, Chigusa Y, Mandai M, Kondoh E. Mechanisms of thrombin-Induced myometrial contractions: Potential targets of progesterone. PLoS ONE. 2020;15:e0231944 pubmed publisher
	Kim M, Park K, Lee J, Ha K, Choi B, Baek J, et al. Weisheng-Tang Ameliorates Acute Ischemic Brain Damage in Mice by Maintaining Blood-Brain Barrier Integrity. Oxid Med Cell Longev. 2019;2019:4379732 pubmed publisher
	Si H, Yang T, Li L, Tian M, Zhou L, Li D, et al. miR-140 Attenuates the Progression of Early-Stage Osteoarthritis by Retarding Chondrocyte Senescence. Mol Ther Nucleic Acids. 2020;19:15-30 pubmed publisher
	Cheng B, Liu Y, Zhao Y, Li Q, Liu Y, Wang J, et al. The role of anthrax toxin protein receptor 1 as a new mechanosensor molecule and its mechanotransduction in BMSCs under hydrostatic pressure. Sci Rep. 2019;9:12642 pubmed publisher
	Komori M, Ago T, Wakisaka Y, Nakamura K, Tachibana M, Yoshikawa Y, et al. Early initiation of a factor Xa inhibitor can attenuate tissue repair and neurorestoration after middle cerebral artery occlusion. Brain Res. 2019;: pubmed publisher
	Liu Z, Zhang Z, Zhang A, Zhang F, Du W, Zhang Y, et al. Osteogenic protein-1 alleviates high glucose microenvironment-caused degenerative changes in nucleus pulposus cells. Biosci Rep. 2019;39: pubmed publisher
	Chen L, Liu G, Li W, Wu X. Chondrogenic differentiation of bone marrow-derived mesenchymal stem cells following transfection with Indian hedgehog and sonic hedgehog using a rotary cell culture system. Cell Mol Biol Lett. 2019;24:16 pubmed publisher
	Jia J, Wang S, Ma L, Yu J, Guo Y, Wang C. The Differential Effects of Leukocyte-Containing and Pure Platelet-Rich Plasma on Nucleus Pulposus-Derived Mesenchymal Stem Cells: Implications for the Clinical Treatment of Intervertebral Disc Degeneration. Stem Cells Int. 2018;2018:7162084 pubmed publisher
	Yang D, Zhu D, Zhu S, Feng F, Gong C, Chen C, et al. 17β-Estradiol/extrogen receptor β alleviates apoptosis and enhances matrix biosynthesis of nucleus pulposus cells through regulating oxidative damage under a high glucose condition. Biomed Pharmacother. 2018;107:1004-1009 pubmed publisher
	Choi C, Yoon H, Drucker K, Langley M, Kleppe L, Scarisbrick I. The Thrombin Receptor Restricts Subventricular Zone Neural Stem Cell Expansion and Differentiation. Sci Rep. 2018;8:9360 pubmed publisher
	Han M, Kim S, Kim H, Yim H, Bencherif S, Kim T, et al. Extracellular matrix-based cryogels for cartilage tissue engineering. Int J Biol Macromol. 2016;93:1410-1419 pubmed publisher
	Kim H, Kim Y, Ahn S, Lee S, Shin H, Choi B. Protease activated receptor-1 antagonist ameliorates the clinical symptoms of experimental autoimmune encephalomyelitis via inhibiting breakdown of blood-brain barrier. J Neurochem. 2015;135:577-88 pubmed publisher
	Bouhenni R, Hart M, Al Jastaneiah S, Alkatan H, Edward D. Immunohistochemical expression and distribution of proteoglycans and collagens in sclerocornea. Int Ophthalmol. 2013;33:691-700 pubmed publisher
	Yurube T, Takada T, Suzuki T, Kakutani K, Maeno K, Doita M, et al. Rat tail static compression model mimics extracellular matrix metabolic imbalances of matrix metalloproteinases, aggrecanases, and tissue inhibitors of metalloproteinases in intervertebral disc degeneration. Arthritis Res Ther. 2012;14:R51 pubmed publisher
	Swearingen C, Chambers M, Lin C, Marimuthu J, Rito C, Carter Q, et al. A short-term pharmacodynamic model for monitoring aggrecanase activity: injection of monosodium iodoacetate (MIA) in rats and assessment of aggrecan neoepitope release in synovial fluid using novel ELISAs. Osteoarthritis Cartilage. 2010;18:1159-66 pubmed publisher
	Little C, Hughes C, Curtis C, Janusz M, Bohne R, Wang Weigand S, et al. Matrix metalloproteinases are involved in C-terminal and interglobular domain processing of cartilage aggrecan in late stage cartilage degradation. Matrix Biol. 2002;21:271-88 pubmed

product information

master code :

NBP1-71770

SKU :

NBP1-71770

product name :

PAR1/Thrombin Receptor Antibody (N2-11) - BSA Free

unit size :

0.1 ml (also 0.025 ml)

description :

The PAR1/Thrombin Receptor Antibody (N2-11) - BSA Free from Novus is a mouse monoclonal antibody to PAR1/Thrombin Receptor. This antibody reacts with human,mouse. The PAR1/Thrombin Receptor Antibody (N2-11) - BSA Free has been validated for the following applications: Immunocytochemistry/ Immunofluorescence,IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunofluorescence,ELISA,Immunohistochemistry.

target :

PAR1/Thrombin Receptor

category :

Primary Antibodies

buffer :

Tris-Glycine and 0.15M NaCl

clonality :

Monoclonal

clone :

N2-11

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

The oligopeptide CNATLDPRSFLL from human Thrombin Receptor. [Swiss-Prot# P25116]

isotype :

IgG1

purity :

Protein G purified

species :

Human,Mouse

theoretical molecular weight :

52 kDa

gene symbol :

F2R

Antibody validation :

Orthogonal Validation

accessionNumbers :

P25116, P30558

applications :

IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunofluorescence,Immunocytochemistry/ Immunofluorescence,ELISA,Immunohistochemistry

USD :

409 USD

alt names :

CF2R, CF2RHTR, coagulation factor II (thrombin) receptor, Coagulation factor II receptor, HTR, PAR1, PAR1PAR-1protease-activated receptor 1, Protease-Activated Receptor 1, Thrombin receptor, TRproteinase-activated receptor 1

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage