product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
ABCG8 Antibody (1B10A5) - BSA Free
catalog :
NBP1-71706
quantity :
0.1 ml (also 0.025 ml)
price :
419 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1B10A5
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human
von Kampen O, Buch S, Nothnagel M, Azocar L, Molina H, Brosch M, et al. Genetic and functional identification of the likely causative variant for cholesterol gallstone disease at the ABCG5/8 lithogenic locus. Hepatology. 2013;57:2407-17 pubmed publisher
  • western blot; mouse
Wang J, Grishin N, Kinch L, Cohen J, Hobbs H, Xie X. Sequences in the nonconsensus nucleotide-binding domain of ABCG5/ABCG8 required for sterol transport. J Biol Chem. 2011;286:7308-14 pubmed publisher
  • immunoprecipitation; mouse
  • immunocytochemistry; mouse
  • western blot; mouse
Wang J, Zhang D, Lei Y, Xu F, Cohen J, Hobbs H, et al. Purification and reconstitution of sterol transfer by native mouse ABCG5 and ABCG8. Biochemistry. 2008;47:5194-204 pubmed publisher
  • immunoprecipitation; mouse
  • western blot; mouse
Zhang D, Graf G, Gerard R, Cohen J, Hobbs H. Functional asymmetry of nucleotide-binding domains in ABCG5 and ABCG8. J Biol Chem. 2006;281:4507-16 pubmed
  • western blot; mouse
  • western blot; human
Graf G, Yu L, Li W, Gerard R, Tuma P, Cohen J, et al. ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion. J Biol Chem. 2003;278:48275-82 pubmed
Xue C, Zeng P, Gong K, Li Q, Feng Z, Wang M, et al. Nogo-B inhibition facilitates cholesterol metabolism to reduce hypercholesterolemia. Cell Rep. 2024;43:114691 pubmed publisher
Wang J, Li L, Hu A, Deng G, Wei J, Li Y, et al. Inhibition of ASGR1 decreases lipid levels by promoting cholesterol excretion. Nature. 2022;608:413-420 pubmed publisher
Nyandwi J, Ko Y, Jin H, Yun S, Park S, Kim H. Rosmarinic Acid Exhibits a Lipid-Lowering Effect by Modulating the Expression of Reverse Cholesterol Transporters and Lipid Metabolism in High-Fat Diet-Fed Mice. Biomolecules. 2021;11: pubmed publisher
Li Z, Kabir I, Tietelman G, Huan C, Fan J, Worgall T, et al. Sphingolipid de novo biosynthesis is essential for intestine cell survival and barrier function. Cell Death Dis. 2018;9:173 pubmed publisher
Gao T, Zhang S, Wang J, Liu L, Wang Y, Cao Z, et al. TLR3 contributes to persistent autophagy and heart failure in mice after myocardial infarction. J Cell Mol Med. 2018;22:395-408 pubmed publisher
Jeon Y, Kim C, Koh J, Chung D, Ha G. Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination. Oncotarget. 2016;7:41811-41824 pubmed publisher
Xu Y, Du F, Meng B, Xie G, Cao J, Fan D, et al. Hepatic overexpression of methionine sulfoxide reductase A reduces atherosclerosis in apolipoprotein E-deficient mice. J Lipid Res. 2015;56:1891-900 pubmed publisher
Xie Y, Fung H, Newberry E, Kennedy S, Luo J, Crooke R, et al. Hepatic Mttp deletion reverses gallstone susceptibility in L-Fabp knockout mice. J Lipid Res. 2014;55:540-8 pubmed publisher
Johnson B, Lee J, Pickert A, Urbatsch I. Bile acids stimulate ATP hydrolysis in the purified cholesterol transporter ABCG5/G8. Biochemistry. 2010;49:3403-11 pubmed publisher
product information
master code :
NBP1-71706
SKU :
NBP1-71706
product name :
ABCG8 Antibody (1B10A5) - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The ABCG8 Antibody (1B10A5) - BSA Free from Novus is a mouse monoclonal antibody to ABCG8. This antibody reacts with human,mouse. The ABCG8 Antibody (1B10A5) - BSA Free has been validated for the following applications: Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin,Knockout Validated.
target :
ABCG8
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
1B10A5
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Full length mouse ABCG8 [Swiss-Prot# Q9DBM0]
isotype :
IgG
purity :
Protein G purified
species :
Human,Mouse
gene symbol :
ABCG8
accessionNumbers :
Q9DBM0
applications :
Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin,Knockout Validated
USD :
419 USD
alt names :
ATP-binding cassette sub-family G member 8, ATP-binding cassette, sub-family G (WHITE), member 8, ATP-binding cassette, sub-family G (WHITE), member 8 (sterolin 2), GBD4ATP-binding cassette, subfamily G, member 8, MGC142217, sterolin 2, sterolin-2, STSL
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.