This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Rabbit Polyclonal DGAT2 Antibody
catalog :
NBP1-71700
quantity :
0.1 ml
price :
299 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, cow, baker's yeast
application :
western blot
citations: 3
Published Application/Species/DilutionReference
Choi Y, Lee C, Lee K, Jung S, Lee B. Increased hepatic Fatty Acid uptake and esterification contribute to tetracycline-induced steatosis in mice. Toxicol Sci. 2015;145:273-82 pubmed publisher
Zeng T, Zhang C, Song F, Zhao X, Xie K. CMZ reversed chronic ethanol-induced disturbance of PPAR-α possibly by suppressing oxidative stress and PGC-1α acetylation, and activating the MAPK and GSK3β pathway. PLoS ONE. 2014;9:e98658 pubmed publisher
Xu N, Zhang S, COLE R, McKinney S, Guo F, Haas J, et al. The FATP1-DGAT2 complex facilitates lipid droplet expansion at the ER-lipid droplet interface. J Cell Biol. 2012;198:895-911 pubmed publisher
product information
Catalog Number :
NBP1-71700
Product Name :
Rabbit Polyclonal DGAT2 Antibody
List Price :
299 USD
Product Type :
Primary Antibodies
Package Size :
0.1 ml
AltNames :
diacylglycerol O-acyltransferase 2, diacylglycerol O-acyltransferase homolog 2, diacylglycerol O-acyltransferase homolog 2 (mouse), diacylglycerol O-acyltransferase-like protein 2, Diglyceride acyltransferase 2, DKFZp686A15125, EC 2.3.1, EC 2.3.1.20, GS1999FULL
Buffer :
PBS, 30% glycerol
Clonality :
Polyclonal
Concentration :
1 mg/ml
Application Summary :
Western Blot
Host :
Rabbit
Immunogen :
A synthetic peptide made to an internal region of the human DGAT2 protein (within residues 100-200). [Swiss-Prot Q96PD7]
Localization :
Endoplasmic reticulum membrane; Multi-pass membrane protein
Preservative :
0.05% Sodium Azide
Purity :
Immunogen affinity purified
CrossReactivity :
Human, yeast and mouse. Immunogen has 100% identity to rat, bovine and porcine, and 86% identity to Xenopus.
Storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Swissprot Human :
Q96PD7
Uses :
This DGAT2 antibody is useful for Western blot, where a band is seen ~43 kDa.
References Product :
Choi YJ, Lee CH, Lee KY et al. Increased Hepatic Fatty Acid Uptake and Esterification Contribute to Tetracycline-Induced Steatosis in Mice Toxicol. Sci. 2015 Mar 04 [PMID: 25745068] (WB, Human, Mouse) Details: DGAT2 antibody used for WB on lysates of liver tissues from mice administered or not with Tetracycline (FIG. 2A), whole cell lysates of HepG2 cells treated or not with Tetracycline, U0126 or PD98059 (FIG. 3C, 5A/B, Supplementary Figure 2B). Antibody also used for WB on lysates of HepG2 cells transfected with mock or HA tagged CA-MEK plasmid as well as on HepG2 cells subjected (FIG. 5A/B) or not to si-RNA mediated double knockdown of DGAT1/2 (FIG. 6A). Zeng T, Zhang CL, Song FY et al. CMZ Reversed Chronic Ethanol-Induced Disturbance of PPAR-a Possibly by Suppressing Oxidative Stress and PGC-1a Acetylation, and Activating the MAPK and GSK3b Pathway PLoS ONE. 2014 Jun 04 [PMID: 24892905] (WB, Mouse) Details: DGAT2 antibody used for WB in specific pathogen-free/SPF male Kun-Ming mice treated or not with chronic ethanol and/or chlormethiazole (CMZ). DGAT2 was studied as rate-limiting enzyme of G synthesis and its levels were found increased in ethanol and CMZ/ethanol group mice liver. (Figure 9A) Xu N, Zhang SO, Cole RA, McKinney SA, Guo F, Haas JT, Bobba S, Farese RV Jr, Mak HY. The FATP1-DGAT2 complex facilitates lipid droplet expansion at the ER-lipid droplet interface J Cell Biol 2012 Aug 27 [PMID: 22927462] (WB, Yeast)
company information
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
novus@novusbio.com
www.novusbio.com
3037301950
headquarters: USA
The mission of Novus Biologicals, LLC is to accelerate scientific discovery by developing and marketing unique products in the forefront of science. Novus Biologicals was organized to provide the biological research community with a mechanism for commercializing unique biological materials. We also focus on continually monitoring scientific trends and supply materials to serve these trends. By making these products widely available to institutional and commercial researchers, Novus Biologicals plays an important role in furthering biological research. All of Novus Biologicals products are supplied with detailed technical information and ongoing support. By serving niche and emerging markets, Novus Biologicals has become specialists in markets and has formed and will continue to form ongoing partnerships with our customers.