| Published Application/Species/Sample/Dilution | Reference |
|---|
- proximity ligation assay; human; fig s3
- immunohistochemistry - paraffin section; human; 1:5000; fig 1
- western blot; human; 1:1000; fig 2
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| Yuan J, Tan J, Rajamani K, Solly E, King E, Lecce L, et al. Fenofibrate Rescues Diabetes-Related Impairment of Ischemia-Mediated Angiogenesis by PPARα-Independent Modulation of Thioredoxin-Interacting Protein. Diabetes. 2019;68:1040-1053 pubmed publisher |
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| Benkafadar N, François F, Affortit C, Casas F, Ceccato J, Menardo J, et al. ROS-Induced Activation of DNA Damage Responses Drives Senescence-Like State in Postmitotic Cochlear Cells: Implication for Hearing Preservation. Mol Neurobiol. 2019;: pubmed publisher |
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| Zhang Y, Chang J, Sun J, Chen L, Yang X, Tang H, et al. Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin to facilitate NHEJ and genome stability. J Cell Sci. 2018;131: pubmed publisher |
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| Chen N, Partridge A, Tuzer F, Cohen J, Nacarelli T, Navas Martin S, et al. Induction of a Senescence-Like Phenotype in Cultured Human Fetal Microglia During HIV-1 Infection. J Gerontol A Biol Sci Med Sci. 2018;73:1187-1196 pubmed publisher |
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| Zaragoza Campillo M, Moran J. Reactive Oxygen Species Evoked by Potassium Deprivation and Staurosporine Inactivate Akt and Induce the Expression of TXNIP in Cerebellar Granule Neurons. Oxid Med Cell Longev. 2017;2017:8930406 pubmed publisher |
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| Croco E, Marchionni S, Bocchini M, Angeloni C, STAMATO T, Stefanelli C, et al. DNA Damage Detection by 53BP1: Relationship to Species Longevity. J Gerontol A Biol Sci Med Sci. 2017;72:763-770 pubmed publisher |
| Bakr A, Köcher S, Volquardsen J, Petersen C, Borgmann K, Dikomey E, et al. Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1. Oncotarget. 2016;7:57679-57693 pubmed publisher |
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| . Inhibition of DNA damage repair by the CDK4/6 inhibitor palbociclib delays irradiated intracranial atypical teratoid rhabdoid tumor and glioblastoma xenograft regrowth. Neuro Oncol. 2016;18:1519-1528 pubmed |
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| Kibe T, Zimmermann M, de Lange T. TPP1 Blocks an ATR-Mediated Resection Mechanism at Telomeres. Mol Cell. 2016;61:236-46 pubmed publisher |
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| Bakr A, Köcher S, Volquardsen J, Reimer R, Borgmann K, Dikomey E, et al. Functional crosstalk between DNA damage response proteins 53BP1 and BRCA1 regulates double strand break repair choice. Radiother Oncol. 2016;119:276-81 pubmed publisher |
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| Belin B, Lee T, Mullins R. DNA damage induces nuclear actin filament assembly by Formin -2 and Spire-½ that promotes efficient DNA repair. [corrected]. elife. 2015;4:e07735 pubmed publisher |
| Yi Y, Park J, Kwak S, Seong Y. Co-treatment with BEZ235 Enhances Sensitivity of BRCA1-negative Breast Cancer Cells to Olaparib. Anticancer Res. 2015;35:3829-38 pubmed |
| Wang X, Li R, Wang X, Fu Q, Ma S. Umbelliferone ameliorates cerebral ischemia-reperfusion injury via upregulating the PPAR gamma expression and suppressing TXNIP/NLRP3 inflammasome. Neurosci Lett. 2015;600:182-7 pubmed publisher |
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| Zhao Y, Li Q, Zhao W, Li J, Sun Y, Liu K, et al. Astragaloside IV and cycloastragenol are equally effective in inhibition of endoplasmic reticulum stress-associated TXNIP/NLRP3 inflammasome activation in the endothelium. J Ethnopharmacol. 2015;169:210-8 pubmed publisher |
| Mathieu A, Verronèse E, Rice G, Fouyssac F, Bertrand Y, Picard C, et al. PRKDC mutations associated with immunodeficiency, granuloma, and autoimmune regulator-dependent autoimmunity. J Allergy Clin Immunol. 2015;135:1578-88.e5 pubmed publisher |
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| Li Y, Li J, Li S, Li Y, Wang X, Liu B, et al. Curcumin attenuates glutamate neurotoxicity in the hippocampus by suppression of ER stress-associated TXNIP/NLRP3 inflammasome activation in a manner dependent on AMPK. Toxicol Appl Pharmacol. 2015;286:53-63 pubmed publisher |
| Walter D, Lier A, Geiselhart A, Thalheimer F, Huntscha S, Sobotta M, et al. Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells. Nature. 2015;520:549-52 pubmed publisher |
| Chen L, Zhu X, Zou Y, Xing J, Gilson E, Lu Y, et al. The topoisomerase II catalytic inhibitor ICRF-193 preferentially targets telomeres that are capped by TRF2. Am J Physiol Cell Physiol. 2015;308:C372-7 pubmed publisher |
| Song J, Li J, Hou F, Wang X, Liu B. Mangiferin inhibits endoplasmic reticulum stress-associated thioredoxin-interacting protein/NLRP3 inflammasome activation with regulation of AMPK in endothelial cells. Metabolism. 2015;64:428-37 pubmed publisher |
| Wu J, Xu X, Li Y, Kou J, Huang F, Liu B, et al. Quercetin, luteolin and epigallocatechin gallate alleviate TXNIP and NLRP3-mediated inflammation and apoptosis with regulation of AMPK in endothelial cells. Eur J Pharmacol. 2014;745:59-68 pubmed publisher |
| Joshi S, Wang W, Peck A, Khan S. Activation of the NLRP3 inflammasome in association with calcium oxalate crystal induced reactive oxygen species in kidneys. J Urol. 2015;193:1684-91 pubmed publisher |
| Saxena G, Chen J, Shalev A. Intracellular shuttling and mitochondrial function of thioredoxin-interacting protein. J Biol Chem. 2010;285:3997-4005 pubmed publisher |
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