beta-Catenin Antibody (12F7) - BSA Free | Novus Biologicals NBP1-54467 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

beta-Catenin Antibody (12F7) - BSA Free

catalog :

NBP1-54467

quantity :

0.1 ml (also 0.025 ml)

price :

449 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

12F7

reactivity :

human, mouse, rat, chicken

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 27

Published Application/Species/Sample/Dilution	Reference
western blot; chicken	Moura R, Carvalho Correia E, daMota P, Correia Pinto J. Canonical Wnt signaling activity in early stages of chick lung development. PLoS ONE. 2014;9:e112388 pubmed publisher
immunocytochemistry; human western blot; human	Nieset J, Redfield A, Jin F, Knudsen K, Johnson K, Wheelock M. Characterization of the interactions of alpha-catenin with alpha-actinin and beta-catenin/plakoglobin. J Cell Sci. 1997;110 ( Pt 8):1013-22 pubmed
western blot; human	Islam S, Carey T, Wolf G, Wheelock M, Johnson K. Expression of N-cadherin by human squamous carcinoma cells induces a scattered fibroblastic phenotype with disrupted cell-cell adhesion. J Cell Biol. 1996;135:1643-54 pubmed
immunoprecipitation; human immunocytochemistry; human western blot; human	Knudsen K, Soler A, Johnson K, Wheelock M. Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin. J Cell Biol. 1995;130:67-77 pubmed
western blot; human	Sacco P, McGranahan T, Wheelock M, Johnson K. Identification of plakoglobin domains required for association with N-cadherin and alpha-catenin. J Biol Chem. 1995;270:20201-6 pubmed
	Aamir K, Sethi G, Afrin M, Hossain C, Jusuf P, Sarker S, et al. Arjunolic acid modulate pancreatic dysfunction by ameliorating pattern recognition receptor and canonical Wnt pathway activation in type 2 diabetic rats. Life Sci. 2023;327:121856 pubmed publisher
	Urasaki Y, Le T. Functional Complementation of Anti-Adipogenic Phytonutrients for Obesity Prevention and Management. Nutrients. 2022;14: pubmed publisher
	Bhatia R, Thompson C, Clement E, Ganguly K, Cox J, Rauth S, et al. Malondialdehyde-Acetaldehyde Extracellular Matrix Protein Adducts Attenuate Unfolded Protein Response During Alcohol and Smoking-Induced Pancreatitis. Gastroenterology. 2022;163:1064-1078.e10 pubmed publisher
	Hino S, Inenaga K, Miyazaki T, Tanaka Mizota C. Suppression of HCT116 Human Colon Cancer Cell Motility by Polymethoxyflavones is Associated with Inhibition of Wnt/β-Catenin Signaling. Nutr Cancer. 2022;74:3662-3669 pubmed publisher
	Sidor J, Gillette M, Dezi L, Untiveros G, Strizzi L. Role of Presenilin-1 in Aggressive Human Melanoma. Int J Mol Sci. 2022;23: pubmed publisher
	Gül H, Ilhan N, Ilhan N, Ozercan I, Kuloglu T. The combined effect of pomegranate extract and tangeretin on the DMBA-induced breast cancer model. J Nutr Biochem. 2021;89:108566 pubmed publisher
	Gonçalves A, Correia Pinto J, Nogueira Silva C. ROBO2 signaling in lung development regulates SOX2/SOX9 balance, branching morphogenesis and is dysregulated in nitrofen-induced congenital diaphragmatic hernia. Respir Res. 2020;21:302 pubmed publisher
	Liu Z, Selby C, Yang Y, Lindsey Boltz L, Cao X, Eynullazada K, et al. Circadian regulation of c-MYC in mice. Proc Natl Acad Sci U S A. 2020;117:21609-21617 pubmed publisher
	Wang L, Liang W, Wang S, Wang Z, Bai H, Jiang Y, et al. Circular RNA expression profiling reveals that circ-PLXNA1 functions in duck adipocyte differentiation. PLoS ONE. 2020;15:e0236069 pubmed publisher
	Eriksson I, Wäster P, Ollinger K. Restoration of lysosomal function after damage is accompanied by recycling of lysosomal membrane proteins. Cell Death Dis. 2020;11:370 pubmed publisher
	Brogden G, Shammas H, Walters F, Maalouf K, Das A, Naim H, et al. Different Trafficking Phenotypes of Niemann-Pick C1 Gene Mutations Correlate with Various Alterations in Lipid Storage, Membrane Composition and Miglustat Amenability. Int J Mol Sci. 2020;21: pubmed publisher
	Dardis A, Zampieri S, Gellera C, Carrozzo R, Cattarossi S, Peruzzo P, et al. Molecular Genetics of Niemann-Pick Type C Disease in Italy: An Update on 105 Patients and Description of 18 NPC1 Novel Variants. J Clin Med. 2020;9: pubmed publisher
	Urasaki Y, Beaumont C, Workman M, Talbot J, Hill D, Le T. Potency Assessment of CBD Oils by Their Effects on Cell Signaling Pathways. Nutrients. 2020;12: pubmed publisher
	Mitroi D, Pereyra Gómez G, Soto Huelin B, Senovilla F, Kobayashi T, Esteban J, et al. NPC1 enables cholesterol mobilization during long-term potentiation that can be restored in Niemann-Pick disease type C by CYP46A1 activation. EMBO Rep. 2019;20:e48143 pubmed publisher
	Heybrock S, Kanerva K, Meng Y, Ing C, Liang A, Xiong Z, et al. Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export. Nat Commun. 2019;10:3521 pubmed publisher
	Bullock W, Hoggatt A, Horan D, Lewis K, Yokota H, Hann S, et al. Expression of a Degradation-Resistant β-Catenin Mutant in Osteocytes Protects the Skeleton From Mechanodeprivation-Induced Bone Wasting. J Bone Miner Res. 2019;34:1964-1975 pubmed publisher
	Chuang C, Wang L, Wong Y, Lin E. Anti-metastatic effects of isolinderalactone via the inhibition of MMP-2 and up regulation of NM23-H1 expression in human lung cancer A549 cells. Oncol Lett. 2018;15:4690-4696 pubmed publisher
	Farjood F, Vargis E. Physical disruption of cell-cell contact induces VEGF expression in RPE cells. Mol Vis. 2017;23:431-446 pubmed
	Ebrahimi Fakhari D, Wahlster L, Bartz F, Werenbeck Ueding J, Praggastis M, Zhang J, et al. Reduction of TMEM97 increases NPC1 protein levels and restores cholesterol trafficking in Niemann-pick type C1 disease cells. Hum Mol Genet. 2016;25:3588-3599 pubmed publisher
	Wu J, Liu J, Ko Y, Wang C, Chung Y, Chu K, et al. Haploinsufficiency of RCBTB1 is associated with Coats disease and familial exudative vitreoretinopathy. Hum Mol Genet. 2016;25:1637-47 pubmed publisher
	Ferrante A, De Nuccio C, Pepponi R, Visentin S, Martire A, Bernardo A, et al. Stimulation of adenosine A2A receptors reduces intracellular cholesterol accumulation and rescues mitochondrial abnormalities in human neural cell models of Niemann-Pick C1. Neuropharmacology. 2016;103:155-62 pubmed publisher
	Li J, Deffieu M, Lee P, Saha P, Pfeffer S. Glycosylation inhibition reduces cholesterol accumulation in NPC1 protein-deficient cells. Proc Natl Acad Sci U S A. 2015;112:14876-81 pubmed publisher

product information

master code :

NBP1-54467

SKU :

NBP1-54467

product name :

beta-Catenin Antibody (12F7) - BSA Free

unit size :

0.1 ml (also 0.025 ml)

description :

The beta-Catenin Antibody (12F7) - BSA Free from Novus is a mouse monoclonal antibody to beta-Catenin. This antibody reacts with avian - chicken,avian - duck,chicken,duck,human,mouse,primate,rat. The beta-Catenin Antibody (12F7) - BSA Free has been validated for the following applications: Simple Western,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunocytochemistry,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Immunohistochemistry-Paraffin,Flow (Intracellular).

target :

beta-Catenin

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

12F7

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Recombinant chicken beta Catenin fused to maltose binding protein. [UniProt# O42486]

isotype :

IgG1

purity :

Protein G purified

species :

Avian - Chicken,Avian - Duck,Chicken,Duck,Human,Mouse,Primate,Rat

theoretical molecular weight :

92 kDa

gene symbol :

CTNNB1

Antibody validation :

Biological Validation

accessionNumbers :

P35222, Q02248, Q9WU82, O42486

applications :

Simple Western,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunocytochemistry,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Immunohistochemistry-Paraffin,Flow (Intracellular)

USD :

449 USD

alt names :

beta 1 (88kD), beta-catenin, catenin (cadherin-associated protein), beta 1, 88kDa, catenin beta-1, CTNNB, DKFZp686D02253, FLJ25606, FLJ37923

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage