product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Mitofusin 1 Antibody - BSA Free
catalog :
NBP1-51841
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 21
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:500; loading ...; fig 6f
  • western blot; mouse; 1:500; loading ...; fig 5c
Xu L, Humphries F, Delagic N, Wang B, Holland A, Edgar K, et al. ECSIT is a critical limiting factor for cardiac function. JCI Insight. 2021;6: pubmed publisher
  • western blot; mouse; loading ...; fig 3b
Chung E, Joiner H, Skelton T, Looten K, Manczak M, Reddy P. Maternal exercise upregulates mitochondrial gene expression and increases enzyme activity of fetal mouse hearts. Physiol Rep. 2017;5: pubmed publisher
Ramasubramanian B, Griffith C, Hanson M, Bunquin L, Reddy A, Hegde V, et al. Protective Effects of Chaya against Mitochondrial and Synaptic Toxicities in the Type 2 Diabetes Mouse Model TallyHO. Cells. 2022;11: pubmed publisher
Chidipi B, Angulo M, Shah S, Rieser M, Ullah G, McDonald T, et al. The dynamin-related protein 1 is decreased and the mitochondrial network is altered in Friedreich's ataxia cardiomyopathy. Int J Biochem Cell Biol. 2022;143:106137 pubmed publisher
Zhang J, He Z, Fedorova J, Logan C, Bates L, Davitt K, et al. Alterations in mitochondrial dynamics with age-related Sirtuin1/Sirtuin3 deficiency impair cardiomyocyte contractility. Aging Cell. 2021;20:e13419 pubmed publisher
Padder R, Bhat Z, Ahmad Z, Singh N, Husain M. DRP1 Promotes BRAFV600E-Driven Tumor Progression and Metabolic Reprogramming in Colorectal Cancer. Front Oncol. 2020;10:592130 pubmed publisher
Bhatti J, Tamarai K, Kandimalla R, Manczak M, Yin X, Ramasubramanian B, et al. Protective effects of a mitochondria-targeted small peptide SS31 against hyperglycemia-induced mitochondrial abnormalities in the liver tissues of diabetic mice, Tallyho/JngJ mice. Mitochondrion. 2021;58:49-58 pubmed publisher
Panes J, Godoy P, Silva Grecchi T, Celis M, Ramírez Molina O, Gavilan J, et al. Changes in PGC-1α/SIRT1 Signaling Impact on Mitochondrial Homeostasis in Amyloid-Beta Peptide Toxicity Model. Front Pharmacol. 2020;11:709 pubmed publisher
Mikłosz A, Łukaszuk B, Baranowski M, Chabowski A, Gorski J. Assessment of the Main Compounds of the Lipolytic System in Treadmill Running Rats: Different Response Patterns between the Right and Left Ventricle. Int J Mol Sci. 2019;20: pubmed publisher
Daemen S, Gemmink A, Brouwers B, Meex R, Huntjens P, Schaart G, et al. Distinct lipid droplet characteristics and distribution unmask the apparent contradiction of the athlete's paradox. Mol Metab. 2018;17:71-81 pubmed publisher
Rogne M, Chu D, Küntziger T, Mylonakou M, Collas P, Tasken K. OPA1-anchored PKA phosphorylates perilipin 1 on S522 and S497 in adipocytes differentiated from human adipose stem cells. Mol Biol Cell. 2018;29:1487-1501 pubmed publisher
Perreault L, Newsom S, Strauss A, Kerege A, Kahn D, Harrison K, et al. Intracellular localization of diacylglycerols and sphingolipids influences insulin sensitivity and mitochondrial function in human skeletal muscle. JCI Insight. 2018;3: pubmed publisher
Lin H, Magrane J, Rattelle A, Stepanova A, Galkin A, Clark E, et al. Early cerebellar deficits in mitochondrial biogenesis and respiratory chain complexes in the KIKO mouse model of Friedreich ataxia. Dis Model Mech. 2017;10:1343-1352 pubmed publisher
Snook L, Trottier S, Worndl E, Bombardier E, Tupling A, Macpherson R. Prior Endurance Training Enhances Beta-Adrenergic Signaling in Epidydimal Adipose from Mice Fed a High-Fat Diet. Obesity (Silver Spring). 2017;25:1699-1706 pubmed publisher
Gemmink A, Bakker L, Guigas B, Kornips E, Schaart G, Meinders A, et al. Lipid droplet dynamics and insulin sensitivity upon a 5-day high-fat diet in Caucasians and South Asians. Sci Rep. 2017;7:42393 pubmed publisher
Wang X, Yang H, Yanagisawa D, Bellier J, Morino K, Zhao S, et al. Mitochondrial ferritin affects mitochondria by stabilizing HIF-1α in retinal pigment epithelium: implications for the pathophysiology of age-related macular degeneration. Neurobiol Aging. 2016;47:168-179 pubmed publisher
Reddy P, Manczak M, Yin X, Grady M, Mitchell A, Kandimalla R, et al. Protective effects of a natural product, curcumin, against amyloid β induced mitochondrial and synaptic toxicities in Alzheimer's disease. J Investig Med. 2016;64:1220-1234 pubmed
Turnbull P, Longo A, Ramos S, Roy B, Ward W, Peters S. Increases in skeletal muscle ATGL and its inhibitor G0S2 following 8 weeks of endurance training in metabolically different rat skeletal muscles. Am J Physiol Regul Integr Comp Physiol. 2016;310:R125-33 pubmed publisher
Turnbull P, Ramos S, Macpherson R, Roy B, Peters S. Characterization of lipolytic inhibitor G(0)/G(1) switch gene-2 protein (G0S2) expression in male Sprague-Dawley rat skeletal muscle compared to relative content of adipose triglyceride lipase (ATGL) and comparitive gene identification-58 (CGI-58). PLoS ONE. 2015;10:e0120136 pubmed publisher
Newsom S, Everett A, Park S, Van Pelt D, Hinko A, Horowitz J. Lipid mixtures containing a very high proportion of saturated fatty acids only modestly impair insulin signaling in cultured muscle cells. PLoS ONE. 2015;10:e0120871 pubmed publisher
Macpherson R, Castelli L, Miotto P, Frendo Cumbo S, Milburn A, Roy B, et al. A maternal high fat diet has long-lasting effects on skeletal muscle lipid and PLIN protein content in rat offspring at young adulthood. Lipids. 2015;50:205-17 pubmed publisher
product information
master code :
NBP1-51841
SKU :
NBP1-51841
product name :
Mitofusin 1 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The Mitofusin 1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to Mitofusin 1. This antibody reacts with human,mouse,ovine,rat. The Mitofusin 1 Antibody - BSA Free has been validated for the following applications: IF/IHC,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence.
target :
Mitofusin 1
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A genomic peptide made to an N-terminal region of human Mitofusin-1 (within residues 5-100). [Swiss-Prot Q8IWA4]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Ovine,Rat
gene symbol :
MFN1
accessionNumbers :
Q8IWA4
applications :
IF/IHC,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence
USD :
409 USD
alt names :
DKFZp762F247, EC 3.6.5, EC 3.6.5.-, FLJ20693, Fzo homolog, hfzo1, hfzo2, MGC41806, mitochondrial transmembrane GTPase Fzo-1, mitochondrial transmembrane GTPase FZO-2, mitofusin 1, mitofusin-1, putative transmembrane GTPase, Transmembrane GTPase MFN1
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.