MDR1 / ABCB1 Antibody (JSB-1) | Novus Biologicals NBP1-51768 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

MDR1 / ABCB1 Antibody (JSB-1)

catalog :

NBP1-51768

quantity :

0.25 ml

price :

279 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

JSB-1

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 4

Reference
D Arrigo P, Russo M, Rea A, Tufano M, Guadagno E, Del Basso De Caro M, et al. A regulatory role for the co-chaperone FKBP51s in PD-L1 expression in glioma. Oncotarget. 2017;8:68291-68304 pubmed publisher
Romano S, Xiao Y, Nakaya M, D Angelillo A, Chang M, Jin J, et al. FKBP51 employs both scaffold and isomerase functions to promote NF-κB activation in melanoma. Nucleic Acids Res. 2015;43:6983-93 pubmed publisher
Romano S, D Angelillo A, Staibano S, Simeone E, D Arrigo P, Ascierto P, et al. Immunomodulatory pathways regulate expression of a spliced FKBP51 isoform in lymphocytes of melanoma patients. Pigment Cell Melanoma Res. 2015;28:442-52 pubmed publisher
Kurihara H, Sato T, Akimoto N, Ogura T, Ito A. Identification and characterization of ABCB1-mediated and non-apoptotic sebum secretion in differentiated hamster sebocytes. Biochim Biophys Acta. 2011;1811:1090-6 pubmed publisher

product information

brand :

Novus

master code :

NBP1-51768

SKU :

NBP1-51768

product name :

MDR1 / ABCB1 Antibody (JSB-1)

description :

The MDR1/ABCB1 Antibody (JSB-1) from Novus is a mouse monoclonal antibody to MDR1/ABCB1. This antibody reacts with human, hamster, mouse (negative), rat (negative). The MDR1/ABCB1 Antibody (JSB-1) has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, In vitro assay.

target :

MDR1 / ABCB1

category :

Primary Antibodies

unit size :

0.25 ml

buffer :

PBS containing 0.1% bovine serum albumin.

clonality :

Monoclonal

clone :

JSB-1

concentration :

0.25 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

The antibody reacts with P Glycoprotein.

isotype :

IgG1

purity :

Sterile filtered

species :

Human, Hamster, Mouse (Negative), Rat (Negative)

specificity :

The antibody JSB-1 reacts with a conserved cytoplasmic epitope of the plasma membrane-associated 170-180 kD glycoprotein, the expression of which is strongly correlated with the degree of multi-drug-resistance (MDR) derived MDR cell lines and human MDR cell lines, including cell lines derived from lung, ovaries and B cell lymphomas. cross reacts with chinese hamster. No cross reactivity with mouse or rat.

gene symbol :

ABCB1

catalog number base :

NBP1-51768

accessionNumbers :

P08183

applications :

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, In vitro assay

USD :

279 USD

alt names :

ABC20, ATP-binding cassette sub-family B member 1, ATP-binding cassette, sub-family B (MDR/TAP), member 1, CD243, CD243 antigen, CLCS, colchicin sensitivity, doxorubicin resistance, EC 3.6.3, EC 3.6.3.44, GP170, IBD13, MDR1MGC163296, multidrug resistance protein 1, P-glycoprotein 1, P-gp, PGY1P-GP

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.