Carbonic Anhydrase IX/CA9 Antibody (2D3) - BSA Free | Novus Biologicals NBP1-51691 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Carbonic Anhydrase IX/CA9 Antibody (2D3) - BSA Free

catalog :

NBP1-51691

quantity :

0.1 ml (also 0.025 ml)

price :

429 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2D3

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 34

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human	Cai C, Alshehri A, Choksi R, Pestronk A. Regional ischemic immune myopathy: a paraneoplastic dermatomyopathy. J Neuropathol Exp Neurol. 2014;73:1126-33 pubmed publisher
western blot; human	Persano L, Pistollato F, Rampazzo E, Della Puppa A, Abbadi S, Frasson C, et al. BMP2 sensitizes glioblastoma stem-like cells to Temozolomide by affecting HIF-1? stability and MGMT expression. Cell Death Dis. 2012;3:e412 pubmed publisher
	Feodoroff M, Hamdan F, Antignani G, Feola S, Fusciello M, Russo S, et al. Enhancing T-cell recruitment in renal cell carcinoma with cytokine-armed adenoviruses. Oncoimmunology. 2024;13:2407532 pubmed publisher
	Rashidi A, Billingham L, Zolp A, Chia T, Silvers C, Katz J, et al. Myeloid cell-derived creatine in the hypoxic niche promotes glioblastoma growth. Cell Metab. 2024;36:62-77.e8 pubmed publisher
	Pascetta S, Kirsh S, Cameron M, Uniacke J. Pharmacological inhibition of neuropeptide Y receptors Y1 and Y5 reduces hypoxic breast cancer migration, proliferation, and signaling. BMC Cancer. 2023;23:494 pubmed publisher
	Hu C, Laux A, Gandjeva A, Wang L, Li M, Brown R, et al. The Effect of Hypoxia-inducible Factor Inhibition on the Phenotype of Fibroblasts in Human and Bovine Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2023;69:73-86 pubmed publisher
	Hamdan F, Ylösmäki E, Chiaro J, Giannoula Y, Long M, Fusciello M, et al. Novel oncolytic adenovirus expressing enhanced cross-hybrid IgGA Fc PD-L1 inhibitor activates multiple immune effector populations leading to enhanced tumor killing in vitro, in vivo and with patient-derived tumor organoids. J Immunother Cancer. 2021;9: pubmed publisher
	Garbati P, Barbieri R, Calderoni M, Baldini F, Nizzari M, Modesto P, et al. Efficacy of a Three Drug-Based Therapy for Neuroblastoma in Mice. Int J Mol Sci. 2021;22: pubmed publisher
	Garbati P, Barbieri R, Cangelosi D, Zanon C, Costa D, Eva A, et al. MCM2 and Carbonic Anhydrase 9 Are Novel Potential Targets for Neuroblastoma Pharmacological Treatment. Biomedicines. 2020;8: pubmed publisher
	Kim S, Shin M, Lee A, Seo B, Park H, Roh S. Improvement of Inflammation through Antioxidant Pathway of Gardeniae Fructus 50% EtOH Extract (GE) from Acute Reflux Esophagitis Rats. Biomed Res Int. 2020;2020:4826176 pubmed publisher
	Li Z, Jiang L, Chew S, Hirayama T, Sekido Y, Toyokuni S. Carbonic anhydrase 9 confers resistance to ferroptosis/apoptosis in malignant mesothelioma under hypoxia. Redox Biol. 2019;26:101297 pubmed publisher
	Ring A, Nguyen C, Smbatyan G, Tripathy D, Yu M, Press M, et al. CBP/β-Catenin/FOXM1 Is a Novel Therapeutic Target in Triple Negative Breast Cancer. Cancers (Basel). 2018;10: pubmed publisher
	Kelly N, Varga J, Specker E, Romeo C, Coomber B, Uniacke J. Hypoxia activates cadherin-22 synthesis via eIF4E2 to drive cancer cell migration, invasion and adhesion. Oncogene. 2018;37:651-662 pubmed publisher
	Dheekollu J, Malecka K, Wiedmer A, Delecluse H, Chiang A, Altieri D, et al. Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency. Oncotarget. 2017;8:7248-7264 pubmed publisher
	Federici C, Lugini L, Marino M, Carta F, Iessi E, Azzarito T, et al. Lansoprazole and carbonic anhydrase IX inhibitors sinergize against human melanoma cells. J Enzyme Inhib Med Chem. 2016;31:119-125 pubmed
	Kapinas K, Kim H, Mandeville M, Martin Buley L, Croce C, Lian J, et al. microRNA-mediated survivin control of pluripotency. J Cell Physiol. 2015;230:63-70 pubmed publisher
	Hoel A, Yu P, Nguyen K, Sui X, Plescia J, Altieri D, et al. Mitochondrial heat shock protein-90 modulates vascular smooth muscle cell survival and the vascular injury response in vivo. Am J Pathol. 2012;181:1151-7 pubmed publisher
	de Souza H, West G, Rebert N, de la Motte C, Drazba J, Fiocchi C. Increased levels of survivin, via association with heat shock protein 90, in mucosal T cells from patients with Crohn's disease. Gastroenterology. 2012;143:1017-26.e9 pubmed publisher
	Lechler P, Balakrishnan S, Schaumburger J, Grassel S, Baier C, Grifka J, et al. The oncofetal gene survivin is re-expressed in osteoarthritis and is required for chondrocyte proliferation in vitro. BMC Musculoskelet Disord. 2011;12:150 pubmed publisher
	Knauer S, Heinrich U, Bier C, Habtemichael N, Docter D, Helling K, et al. An otoprotective role for the apoptosis inhibitor protein survivin. Cell Death Dis. 2010;1:e51 pubmed publisher
	Habtemichael N, W nsch D, Bier C, Tillmann S, Unruhe B, Frauenknecht K, et al. Cloning and functional characterization of the guinea pig apoptosis inhibitor protein Survivin. Gene. 2010;469:9-17 pubmed publisher
	Habtemichael N, Heinrich U, Knauer S, Schmidtmann I, Bier C, Docter D, et al. Expression analysis suggests a potential cytoprotective role of Birc5 in the inner ear. Mol Cell Neurosci. 2010;45:297-305 pubmed publisher
	Huang H, Fletcher L, Beeharry N, Daniel R, Kao G, Yen T, et al. Abnormal cytokinesis after X-irradiation in tumor cells that override the G2 DNA damage checkpoint. Cancer Res. 2008;68:3724-32 pubmed publisher
	Levkau B, Schäfers M, Wohlschlaeger J, von Wnuck Lipinski K, Keul P, Hermann S, et al. Survivin determines cardiac function by controlling total cardiomyocyte number. Circulation. 2008;117:1583-93 pubmed publisher
	Hino R, Uozaki H, Inoue Y, Shintani Y, Ushiku T, Sakatani T, et al. Survival advantage of EBV-associated gastric carcinoma: survivin up-regulation by viral latent membrane protein 2A. Cancer Res. 2008;68:1427-35 pubmed publisher
	Brocardo M, Lei Y, Tighe A, Taylor S, Mok M, Henderson B. Mitochondrial targeting of adenomatous polyposis coli protein is stimulated by truncating cancer mutations: regulation of Bcl-2 and implications for cell survival. J Biol Chem. 2008;283:5950-9 pubmed
	Ryan B, O Donovan N, Browne B, O SHEA C, Crown J, Hill A, et al. Expression of survivin and its splice variants survivin-2B and survivin-DeltaEx3 in breast cancer. Br J Cancer. 2005;92:120-4 pubmed
	Ansell S, Arendt B, Grote D, Jelinek D, Novak A, Wellik L, et al. Inhibition of survivin expression suppresses the growth of aggressive non-Hodgkin's lymphoma. Leukemia. 2004;18:616-23 pubmed
	Koyama S. Differential expression of intracellular apoptotic signaling molecules in tumor and tumor-infiltrating lymphocytes during development of invasion and/or metastasis of gastric carcinoma. Dig Dis Sci. 2003;48:2290-300 pubmed
	Ku J, Kwak C, Lee H, Park H, Lee E, Lee S. Expression of survivin, a novel inhibitor of apoptosis, in superficial transitional cell carcinoma of the bladder. J Urol. 2004;171:631-5 pubmed
	Xu Z, Zhao R, Ding T, Tran T, Zhang W, Pandolfi P, et al. Promyelocytic leukemia protein 4 induces apoptosis by inhibition of survivin expression. J Biol Chem. 2004;279:1838-44 pubmed
	Allen S, Florell S, Hanks A, Alexander A, Diedrich M, Altieri D, et al. Survivin expression in mouse skin prevents papilloma regression and promotes chemical-induced tumor progression. Cancer Res. 2003;63:567-72 pubmed
	Fortugno P, Wall N, Giodini A, O Connor D, Plescia J, Padgett K, et al. Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function. J Cell Sci. 2002;115:575-85 pubmed
	Zhu L, Fukuda S, Cordis G, Das D, Maulik N. Anti-apoptotic protein survivin plays a significant role in tubular morphogenesis of human coronary arteriolar endothelial cells by hypoxic preconditioning. FEBS Lett. 2001;508:369-74 pubmed

product information

master code :

NBP1-51691

SKU :

NBP1-51691

product name :

Carbonic Anhydrase IX/CA9 Antibody (2D3) - BSA Free

unit size :

0.1 ml (also 0.025 ml)

description :

The Carbonic Anhydrase IX/CA9 Antibody (2D3) - BSA Free from Novus is a mouse monoclonal antibody to Carbonic Anhydrase IX/CA9. This antibody reacts with human,mouse. The Carbonic Anhydrase IX/CA9 Antibody (2D3) - BSA Free has been validated for the following applications: IF/IHC,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,ELISA,Immunohistochemistry,Immunohistochemistry-Paraffin,Flow (Intracellular),CyTOF-ready.

target :

Carbonic Anhydrase IX/CA9

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

2D3

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

This Carbonic Anhydrase IX/CA9 Antibody (2D3) was made to a purified recombinant fragment of human Carbonic Anhydrase IX expressed in E. coli [UniProt# Q16790].

isotype :

IgG1

purity :

Protein A or G purified

species :

Human,Mouse

theoretical molecular weight :

50 kDa

gene symbol :

CA9

accessionNumbers :

Q16790

applications :

IF/IHC,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,ELISA,Immunohistochemistry,Immunohistochemistry-Paraffin,Flow (Intracellular),CyTOF-ready

USD :

429 USD

alt names :

CAIX, CA-IX, Carbonate dehydratase IX, carbonic anhydrase 9, carbonic anhydrase IX, carbonic dehydratase, EC 4.2.1.1, G250, Membrane antigen MN, MN, P54/58N, PMW1, RCC-associated antigen G250, RCC-associated protein G250, Renal cell carcinoma-associated antigen G250

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage