product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
SLC22A1 Antibody (2C5)
catalog :
NBP1-51684
quantity :
0.1 ml (also 0.025 ml)
price :
449 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2C5
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...
Zhang Y, Boxberger K, Hagenbuch B. Organic anion transporting polypeptide 1B3 can form homo- and hetero-oligomers. PLoS ONE. 2017;12:e0180257 pubmed publisher
Wittern C, Schr xf6 der S, Jensen O, Brockm xf6 ller J, Gebauer L. Comprehensive characterization of the OCT1 phenylalanine-244-alanine substitution reveals highly substrate-dependent effects on transporter function. J Biol Chem. 2024;300:107835 pubmed publisher
Haas M, Ackermann G, K xfc pper J, Glatt H, Schrenk D, Fahrer J. OCT1-dependent uptake of structurally diverse pyrrolizidine alkaloids in human liver cells is crucial for their genotoxic and cytotoxic effects. Arch Toxicol. 2023;97:3259-3271 pubmed publisher
Redeker K, Jensen O, Gebauer L, Meyer T xf6 nnies M, Brockm xf6 ller J. Atypical Substrates of the Organic Cation Transporter 1. Biomolecules. 2022;12: pubmed publisher
Meyer M, Schreier P, Basaran M, Vlasova S, Seitz T, Brockm xf6 ller J, et al. Amino acids in transmembrane helix 1 confer major functional differences between human and mouse orthologs of the polyspecific membrane transporter OCT1. J Biol Chem. 2022;298:101974 pubmed publisher
Römer S, Meyer M, Klein K, Schneider L, Matthaei J, Tzvetkova A, et al. Effects of a Common Eight Base Pairs Duplication at the Exon 7-Intron 7 Junction on Splicing, Expression, and Function of OCT1. Front Pharmacol. 2021;12:661480 pubmed publisher
Kim H, Raffler J, Lu W, Lee J, Abbey D, Saleheen D, et al. Fine Mapping and Functional Analysis Reveal a Role of SLC22A1 in Acylcarnitine Transport. Am J Hum Genet. 2017;101:489-502 pubmed publisher
Sekhar G, Georgian A, Sanderson L, Vizcay Barrena G, Brown R, Muresan P, et al. Organic cation transporter 1 (OCT1) is involved in pentamidine transport at the human and mouse blood-brain barrier (BBB). PLoS ONE. 2017;12:e0173474 pubmed publisher
Seitz T, Stalmann R, Dalila N, Chen J, Pojar S, Dos Santos Pereira J, et al. Global genetic analyses reveal strong inter-ethnic variability in the loss of activity of the organic cation transporter OCT1. Genome Med. 2015;7:56 pubmed publisher
Boxberger K, Hagenbuch B, Lampe J. Common drugs inhibit human organic cation transporter 1 (OCT1)-mediated neurotransmitter uptake. Drug Metab Dispos. 2014;42:990-5 pubmed publisher
product information
master code :
NBP1-51684
SKU :
NBP1-51684
product name :
SLC22A1 Antibody (2C5)
unit size :
0.1 ml (also 0.025 ml)
description :
The SLC22A1 Antibody (2C5) from Novus is a mouse monoclonal antibody to SLC22A1. This antibody reacts with human,mouse. The SLC22A1 Antibody (2C5) has been validated for the following applications: IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Electron Microscopy,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,ELISA,Immunohistochemistry.
target :
SLC22A1
category :
Primary Antibodies
buffer :
Ascites
clonality :
Monoclonal
clone :
2C5
conjugate :
Unconjugated
host :
Mouse
immunogen :
Purified recombinant fragment of human SLC22A1 expressed in E. Coli.
isotype :
IgG1
purity :
Unpurified
species :
Human,Mouse
theoretical molecular weight :
61.2 kDa
gene symbol :
SLC22A1
accessionNumbers :
O15245
applications :
IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Electron Microscopy,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,ELISA,Immunohistochemistry
USD :
449 USD
alt names :
hOCT1, oct1_cds, OCT1solute carrier family 22 member 1, Organic cation transporter 1, solute carrier family 22 (organic cation transporter), member 1
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.