p62/SQSTM1 Antibody | Novus Biologicals NBP1-49956 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

p62/SQSTM1 Antibody

catalog :

NBP1-49956

quantity :

0.1 ml

price :

469 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 17

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 6a	Goiran T, Duplan E, Rouland L, El Manaa W, Lauritzen I, Dunys J, et al. Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation. Cell Death Differ. 2018;25:873-884 pubmed publisher
	Gautam S, Zhang L, Lee C, Arnaoutova I, Chen H, Resaz R, et al. Molecular mechanism underlying impaired hepatic autophagy in glycogen storage disease type Ib. Hum Mol Genet. 2023;32:262-275 pubmed publisher
	V xe1 mos A, Shaw A, Varga K, Csom xf3 s I, Mocs xe1 r G, Balajthy Z, et al. Mitophagy Mediates the Beige to White Transition of Human Primary Subcutaneous Adipocytes Ex Vivo. Pharmaceuticals (Basel). 2022;15: pubmed publisher
	McKinney J, Seferovic M, Major A, Suter M, Tardif S, Patterson J, et al. Placental Autophagy and Viral Replication Co-localize in Human and Non-human Primate Placentae Following Zika Virus Infection: Implications for Therapeutic Interventions. Front Virol. 2021;1: pubmed publisher
	El Manaa W, Duplan E, Goiran T, Lauritzen I, Vaillant Beuchot L, Lacas Gervais S, et al. Transcription- and phosphorylation-dependent control of a functional interplay between XBP1s and PINK1 governs mitophagy and potentially impacts Parkinson disease pathophysiology. Autophagy. 2021;:1-23 pubmed publisher
	Sukseree S, Bakiri L, Palomo Irigoyen M, Uluçkan O, Petzelbauer P, Wagner E. Sequestosome 1/p62 enhances chronic skin inflammation. J Allergy Clin Immunol. 2021;147:2386-2393.e4 pubmed publisher
	Szatm xe1 ri T xf3 th M, Shaw A, Csom xf3 s I, Mocs xe1 r G, Fischer Posovszky P, Wabitsch M, et al. Thermogenic Activation Downregulates High Mitophagy Rate in Human Masked and Mature Beige Adipocytes. Int J Mol Sci. 2020;21: pubmed publisher
	Thomas A, Samykutty A, Gomez Gutierrez J, Yin W, Egger M, McNally M, et al. Actively Targeted Nanodelivery of Echinomycin Induces Autophagy-Mediated Death in Chemoresistant Pancreatic Cancer In Vivo. Cancers (Basel). 2020;12: pubmed publisher
	Gautam S, Zhang L, Arnaoutova I, Lee C, Mansfield B, Chou J. The signaling pathways implicated in impairment of hepatic autophagy in glycogen storage disease type Ia. Hum Mol Genet. 2020;29:834-844 pubmed publisher
	Cho J, Lee Y, Bae S, Chou J. Activation of tumor-promoting pathways implicated in hepatocellular adenoma/carcinoma, a long-term complication of glycogen storage disease type Ia. Biochem Biophys Res Commun. 2020;522:1-7 pubmed publisher
	Chamoun Emanuelli A, Bryan L, Cohen N, Tetrault T, Szule J, Barhoumi R, et al. NSAIDs disrupt intestinal homeostasis by suppressing macroautophagy in intestinal epithelial cells. Sci Rep. 2019;9:14534 pubmed publisher
	Llanos S, Megias D, Blanco Aparicio C, Hernández Encinas E, Rovira M, Pietrocola F, et al. Lysosomal trapping of palbociclib and its functional implications. Oncogene. 2019;38:3886-3902 pubmed publisher
	Cho J, Lee Y, Starost M, Mansfield B, Chou J. Gene therapy prevents hepatic tumor initiation in murine glycogen storage disease type Ia at the tumor-developing stage. J Inherit Metab Dis. 2019;42:459-469 pubmed publisher
	Karras P, Riveiro Falkenbach E, Cañón E, Tejedo C, Calvo T, Martínez Herranz R, et al. p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors. Cancer Cell. 2019;35:46-63.e10 pubmed publisher
	Garcia Fernandez M, Karras P, Checinska A, Cañón E, Calvo G, Gomez Lopez G, et al. Metastatic risk and resistance to BRAF inhibitors in melanoma defined by selective allelic loss of ATG5. Autophagy. 2016;12:1776-1790 pubmed
	Gontier G, George C, Chaker Z, Holzenberger M, AÃ¯d S. Blocking IGF Signaling in Adult Neurons Alleviates Alzheimer's Disease Pathology through Amyloid-Î² Clearance. J Neurosci. 2015;35:11500-13 pubmed publisher
	Gispert S, Brehm N, Weil J, Seidel K, RÃ¼b U, Kern B, et al. Potentiation of neurotoxicity in double-mutant mice with Pink1 ablation and A53T-SNCA overexpression. Hum Mol Genet. 2015;24:1061-76 pubmed publisher

product information

master code :

NBP1-49956

SKU :

NBP1-49956

product name :

p62/SQSTM1 Antibody

unit size :

0.1 ml

description :

The p62/SQSTM1 Antibody from Novus is a rabbit polyclonal antibody to p62/SQSTM1. This antibody reacts with human,mouse. The p62/SQSTM1 Antibody has been validated for the following applications: Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry,IF/IHC,Knockout Validated,Immunoprecipitation.

target :

p62/SQSTM1

category :

Primary Antibodies

buffer :

TBS and 0.1% BSA

clonality :

Polyclonal

concentration :

0.2 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

The immunogen for this product maps to a region between residue 425 and 440 of human p62/SQSTM1 using the numbering given in entry NP_003891.1 (GeneID 8878).

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human,Mouse

theoretical molecular weight :

47.7 kDa

gene symbol :

SQSTM1

Antibody validation :

Independent Anitbodies

accessionNumbers :

Q13501

applications :

Immunohistochemistry,Western Blot,IF/IHC,Immunohistochemistry-Paraffin,Knockout Validated,Immunoprecipitation

USD :

469 USD

alt names :

A170, Autophagy Receptor P62, DMRV, EBI3-associated protein of 60 kDa, EBI3-associated protein p60, EBIAP, FTDALS3, NADGP, ORCA, OSIL, oxidative stress induced like, p60PDB3, p62, p62B, Paget disease of bone 3, PDB3, phosphotyrosine independent ligand for the Lck SH2 domain p62, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, sequestosome 1, sequestosome-1, Ubiquitin-binding protein p62, ZIP3

storage :

Store at 4C. Do not freeze.

more info or order :

Novus Biologicals product webpage