product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
TGN46 Antibody - BSA Free
catalog :
NBP1-49643
quantity :
0.1 ml (also 0.025 ml)
price :
479 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
13H12
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 60
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:100; fig 3
Pillay S, Meyer N, Puschnik A, Davulcu O, Diep J, Ishikawa Y, et al. An essential receptor for adeno-associated virus infection. Nature. 2016;530:108-12 pubmed publisher
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Read C, Ali A, Stephenson D, MacKnight H, Maus K, Cockburn C, et al. Ceramide-1-phosphate is a regulator of Golgi structure and is co-opted by the obligate intracellular bacterial pathogen Anaplasma phagocytophilum. MBio. 2024;15:e0029924 pubmed publisher
Gu S, Maurya S, Lona A, Borrega Roman L, SALANGA C, Gonzalez D, et al. Ligand-Dependent Mechanisms of C-C Chemokine Receptor 5 (CCR5) Trafficking Revealed by APEX2 Proximity Labeling Proteomics. bioRxiv. 2023;: pubmed publisher
Kim H, Lee Y, Lee S, Park B. HCMV-encoded viral protein US12 promotes autophagy by inducing autophagy flux. Biochem Biophys Res Commun. 2023;654:94-101 pubmed publisher
Miller A, Houlihan P, Matamala E, Cabezas Bratesco D, Lee G, Cristofori Armstrong B, et al. The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins. elife. 2023;12: pubmed publisher
Steimle B, Bailey D, Smith F, Rosenblum S, Kosman D. Calcium and the Ca-ATPase SPCA1 modulate plasma membrane abundance of ZIP8 and ZIP14 to regulate Mn(II) uptake in brain microvascular endothelial cells. J Biol Chem. 2022;298:102211 pubmed publisher
Song P, Peng J, Omrane M, Cai T, Samuel D, Gassama Diagne A. Septin 9 and phosphoinositides regulate lysosome localization and their association with lipid droplets. iScience. 2022;25:104288 pubmed publisher
Okada T, Nishida S, Zhang L, Ibrahim Mohamed N, Wang T, Ijuin T, et al. Constitutive activation of S1P receptors at the trans-Golgi network is required for surface transport carrier formation. iScience. 2021;24:103351 pubmed publisher
Kutchukian C, Vivas O, Casas M, Jones J, Tiscione S, Simo S, et al. NPC1 regulates the distribution of phosphatidylinositol 4-kinases at Golgi and lysosomal membranes. EMBO J. 2021;40:e105990 pubmed publisher
Bakkar N, Starr A, Rabichow B, Lorenzini I, McEachin Z, Kraft R, et al. The M1311V variant of ATP7A is associated with impaired trafficking and copper homeostasis in models of motor neuron disease. Neurobiol Dis. 2021;149:105228 pubmed publisher
Roy S, McCann C, Ralle M, Ray K, Ray J, Lutsenko S, et al. Analysis of Wilson disease mutations revealed that interactions between different ATP7B mutants modify their properties. Sci Rep. 2020;10:13487 pubmed publisher
Leier H, Weinstein J, Kyle J, Lee J, Bramer L, Stratton K, et al. A global lipid map defines a network essential for Zika virus replication. Nat Commun. 2020;11:3652 pubmed publisher
Krassovka J, Suschek C, Prost M, Grotheer V, Schiefer J, Demir E, et al. The impact of non-toxic blue light (453 nm) on cellular antioxidative capacity, TGF-β1 signaling, and myofibrogenesis of human skin fibroblasts. J Photochem Photobiol B. 2020;209:111952 pubmed publisher
McPhail J, Lyoo H, Pemberton J, Hoffmann R, van Elst W, Strating J, et al. Characterization of the c10orf76-PI4KB complex and its necessity for Golgi PI4P levels and enterovirus replication. EMBO Rep. 2020;21:e48441 pubmed publisher
Dudek A, Zabaleta N, Zinn E, Pillay S, Zengel J, Porter C, et al. GPR108 Is a Highly Conserved AAV Entry Factor. Mol Ther. 2019;: pubmed publisher
Ko P, Woodrow C, Dubreuil M, Martin B, Skouta R, Bassik M, et al. A ZDHHC5-GOLGA7 Protein Acyltransferase Complex Promotes Nonapoptotic Cell Death. Cell Chem Biol. 2019;26:1716-1724.e9 pubmed publisher
Gu Y, Princely Abudu Y, Kumar S, Bissa B, Choi S, Jia J, et al. Mammalian Atg8 proteins regulate lysosome and autolysosome biogenesis through SNAREs. EMBO J. 2019;38:e101994 pubmed publisher
Del Olmo T, Lacarrière Keïta C, Normandin C, Jean D, Boisvert F, Jean S. RAB21 interacts with TMED10 and modulates its localization and abundance. Biol Open. 2019;8: pubmed publisher
Modi A, Singh M, Gutti G, Shanker O, Singh V, Singh S, et al. Benzothiazole derivative bearing amide moiety induces p53-mediated apoptosis in HPV16 positive cervical cancer cells. Invest New Drugs. 2019;: pubmed publisher
Srivastava S, Battu M, Khan M, Nandicoori V, Mukhopadhyay S. Mycobacterium tuberculosis PPE2 Protein Interacts with p67phox and Inhibits Reactive Oxygen Species Production. J Immunol. 2019;203:1218-1229 pubmed publisher
Eiraku N, Chiba N, Nakamura T, Amir M, Seong C, Ohnishi T, et al. BMP9 directly induces rapid GSK3-β phosphorylation in a Wnt-independent manner through class I PI3K-Akt axis in osteoblasts. FASEB J. 2019;:fj201900733RR pubmed publisher
Mishra P, Paital B, Jena S, Swain S, Kumar S, Yadav M, et al. Possible activation of NRF2 by Vitamin E/Curcumin against altered thyroid hormone induced oxidative stress via NFĸB/AKT/mTOR/KEAP1 signalling in rat heart. Sci Rep. 2019;9:7408 pubmed publisher
Del Olmo T, Lauzier A, Normandin C, Larcher R, Lecours M, Jean D, et al. APEX2-mediated RAB proximity labeling identifies a role for RAB21 in clathrin-independent cargo sorting. EMBO Rep. 2019;20: pubmed publisher
Roberts B, Severance Z, Bensen R, Le A, Kothapalli N, Nuñez J, et al. Transient Compound Treatment Induces a Multigenerational Reduction of Oxysterol-Binding Protein (OSBP) Levels and Prophylactic Antiviral Activity. ACS Chem Biol. 2019;14:276-287 pubmed publisher
Capone V, Clemente E, Restelli E, Di Campli A, Sperduti S, Ornaghi F, et al. PERK inhibition attenuates the abnormalities of the secretory pathway and the increased apoptotic rate induced by SIL1 knockdown in HeLa cells. Biochim Biophys Acta Mol Basis Dis. 2018;1864:3164-3180 pubmed publisher
Shwetha S, Sharma G, Raheja H, Goel A, Aggarwal R, Das S. Interaction of miR-125b-5p with Human antigen R mRNA: Mechanism of controlling HCV replication. Virus Res. 2018;258:1-8 pubmed publisher
Wild P, Kaech A, Schraner E, Walser L, Ackermann M. Endoplasmic reticulum-to-Golgi transitions upon herpes virus infection. F1000Res. 2017;6:1804 pubmed publisher
van Deel E, Octavia Y, de Waard M, de Boer M, Duncker D. Exercise Training Has Contrasting Effects in Myocardial Infarction and Pressure Overload Due to Divergent Endothelial Nitric Oxide Synthase Regulation. Int J Mol Sci. 2018;19: pubmed publisher
Melia C, van der Schaar H, de Jong A, Lyoo H, Snijder E, Koster A, et al. The Origin, Dynamic Morphology, and PI4P-Independent Formation of Encephalomyocarditis Virus Replication Organelles. MBio. 2018;9: pubmed publisher
Ibar C, Kirichenko E, Keepers B, Enners E, Fleisch K, Irvine K. Tension-dependent regulation of mammalian Hippo signaling through LIMD1. J Cell Sci. 2018;131: pubmed publisher
Winzi M, Casas Vila N, Paszkowski Rogacz M, Ding L, Noack S, Theis M, et al. The long noncoding RNA lncR492 inhibits neural differentiation of murine embryonic stem cells. PLoS ONE. 2018;13:e0191682 pubmed publisher
Yen J, Wei L, Chen L, Chen L, Hung C, Wang S, et al. Subcellular Localization and Functional Characterization of GII.4 Norovirus-Encoded NTPase. J Virol. 2018;92: pubmed publisher
Badawy S, Okada T, Kajimoto T, Ijuin T, Nakamura S. DHHC5-mediated palmitoylation of S1P receptor subtype 1 determines G-protein coupling. Sci Rep. 2017;7:16552 pubmed publisher
Polpitiya Arachchige S, Henke W, Pramanik A, Kalamvoki M, Stephens E. Analysis of Select Herpes Simplex Virus 1 (HSV-1) Proteins for Restriction of Human Immunodeficiency Virus Type 1 (HIV-1): HSV-1 gM Protein Potently Restricts HIV-1 by Preventing Intracellular Transport and Processing of Env gp160. J Virol. 2018;92: pubmed publisher
Padhy B, Hayat B, Nanda G, Mohanty P, Alone D. Pseudoexfoliation and Alzheimer's associated CLU risk variant, rs2279590, lies within an enhancer element and regulates CLU, EPHX2 and PTK2B gene expression. Hum Mol Genet. 2017;26:4519-4529 pubmed publisher
Becher A, Eiseler T, Porzner M, Walther P, Keil R, Bobrovich S, et al. The armadillo protein p0071 controls KIF3 motor transport. J Cell Sci. 2017;130:3374-3387 pubmed publisher
Sarabhai T, Peter C, Bär A, Windolf J, Relja B, Wesselborg S, et al. Serum α-1 Antitrypsin (AAT) antagonizes intrinsic apoptosis induction in neutrophils from patients with systemic inflammatory response syndrome. PLoS ONE. 2017;12:e0177450 pubmed publisher
Serfass J, Takahashi Y, Zhou Z, Kawasawa Y, Liu Y, Tsotakos N, et al. Endophilin B2 facilitates endosome maturation in response to growth factor stimulation, autophagy induction, and influenza A virus infection. J Biol Chem. 2017;292:10097-10111 pubmed publisher
Drake M, Brennan B, Briley K, Bart S, Sherman E, Szemiel A, et al. A role for glycolipid biosynthesis in severe fever with thrombocytopenia syndrome virus entry. PLoS Pathog. 2017;13:e1006316 pubmed publisher
Yeyati P, Schiller R, Mali G, Kasioulis I, Kawamura A, Adams I, et al. KDM3A coordinates actin dynamics with intraflagellar transport to regulate cilia stability. J Cell Biol. 2017;216:999-1013 pubmed publisher
Bologna Molina R, Takeda Y, Kuga T, Chosa N, Kitagawa M, Takata T, et al. Expression of Wilms' tumor 1 (WT1) in ameloblastomas. J Oral Sci. 2016;58:407-13 pubmed publisher
Titos E, Rius B, López Vicario C, Alcaraz Quiles J, García Alonso V, Lopategi A, et al. Signaling and Immunoresolving Actions of Resolvin D1 in Inflamed Human Visceral Adipose Tissue. J Immunol. 2016;197:3360-3370 pubmed
Mishra D, Singh S, Narayan G. Curcumin Induces Apoptosis in Pre-B Acute Lymphoblastic Leukemia Cell Lines Via PARP-1 Cleavage. Asian Pac J Cancer Prev. 2016;17:3865-9 pubmed
Spasova M, Chen X, Sadowska G, Horton E, Lim Y, Stonestreet B. Ischemia reduces inter-alpha inhibitor proteins in the brain of the ovine fetus. Dev Neurobiol. 2017;77:726-737 pubmed publisher
Grimberg Peters D, Büren C, Windolf J, Wahlers T, Paunel Görgülü A. Hyperbaric Oxygen Reduces Production of Reactive Oxygen Species in Neutrophils from Polytraumatized Patients Yielding in the Inhibition of p38 MAP Kinase and Downstream Pathways. PLoS ONE. 2016;11:e0161343 pubmed publisher
Takahashi Y, Tsotakos N, Liu Y, Young M, Serfass J, Tang Z, et al. The Bif-1-Dynamin 2 membrane fission machinery regulates Atg9-containing vesicle generation at the Rab11-positive reservoirs. Oncotarget. 2016;7:20855-68 pubmed publisher
Srinivas C, Ramaiah M, Lavanya A, Yerramsetty S, Kavi Kishor P, Basha S, et al. Novel Etoposide Analogue Modulates Expression of Angiogenesis Associated microRNAs and Regulates Cell Proliferation by Targeting STAT3 in Breast Cancer. PLoS ONE. 2015;10:e0142006 pubmed publisher
Sun S, Reddy B, Irvine K. Localization of Hippo signalling complexes and Warts activation in vivo. Nat Commun. 2015;6:8402 pubmed publisher
Bernardes D, Brambilla R, Bracchi Ricard V, Karmally S, Dellarole A, Carvalho Tavares J, et al. Prior regular exercise improves clinical outcome and reduces demyelination and axonal injury in experimental autoimmune encephalomyelitis. J Neurochem. 2016;136 Suppl 1:63-73 pubmed publisher
Kumar S, Mamidi P, Kumar A, Basantray I, Bramha U, Dixit A, et al. Development of novel antibodies against non-structural proteins nsP1, nsP3 and nsP4 of chikungunya virus: potential use in basic research. Arch Virol. 2015;160:2749-61 pubmed publisher
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Helmering J, Juan T, Li C, Chhoa M, Baron W, Gyuris T, et al. A mutation in Ampd2 is associated with nephrotic syndrome and hypercholesterolemia in mice. Lipids Health Dis. 2014;13:167 pubmed publisher
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Das I, Basantray I, Mamidi P, Nayak T, B M P, Chattopadhyay S, et al. Heat shock protein 90 positively regulates Chikungunya virus replication by stabilizing viral non-structural protein nsP2 during infection. PLoS ONE. 2014;9:e100531 pubmed publisher
Mellergaard M, Skovbakke S, Schneider C, Lauridsen F, Andresen L, Jensen H, et al. N-glycosylation of asparagine 8 regulates surface expression of major histocompatibility complex class I chain-related protein A (MICA) alleles dependent on threonine 24. J Biol Chem. 2014;289:20078-91 pubmed publisher
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product information
master code :
NBP1-49643
SKU :
NBP1-49643
product name :
TGN46 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The TGN46 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to TGN46. This antibody reacts with bovine,human,monkey,primate - macaca mulatta (rhesus macaque). The TGN46 Antibody - BSA Free has been validated for the following applications: Immunocytochemistry/ Immunofluorescence,Western Blot,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunoblotting,Flow (Intracellular),Knockout Validated.
target :
TGN46
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Partial recombinant protein made to an internal region of the human TGN46 protein (within residues 200-350). [Swiss-Prot: O43493]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Bovine,Human,Monkey,Primate - Macaca mulatta (Rhesus Macaque)
gene symbol :
TGOLN2
Antibody validation :
Knockout/Knockdown
accessionNumbers :
O43493
applications :
Western Blot,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunoblotting,Flow (Intracellular),Knockout Validated
USD :
479 USD
alt names :
TGN 46, TGN 48, TGN 51, TGN38, TGN-38, TGN38 homolog, TGN46, TGN-46, TGN48, TGN51, TGOLN 2, TGOLN2, trans golgi network 38, trans golgi network 46, Trans Golgi network integral membrane protein 2, Trans Golgi network integral membrane protein 2 [Precursor], Trans Golgi network protein (46 48 51kD isoforms), Trans golgi network protein 2, Trans Golgi network protein TGN51, Trans-Golgi network integral membrane protein 2, Trans-Golgi network protein 2, Trans-Golgi network protein TGN51, TTGN 2, TTGN2
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.