product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody - BSA Free
catalog :
NBP1-49600
quantity :
0.1 ml (also 0.025 ml)
price :
399 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; loading ...; fig 5a
Liao T, Lin C, Jiang J, Yang S, Teng H, Yang M. Harnessing stemness and PD-L1 expression by AT-rich interaction domain-containing protein 3B in colorectal cancer. Theranostics. 2020;10:6095-6112 pubmed publisher
Thaler R, Khani F, Sturmlechner I, Dehghani S, Denbeigh J, Zhou X, et al. Vitamin C epigenetically controls osteogenesis and bone mineralization. Nat Commun. 2022;13:5883 pubmed publisher
Claycombe Larson K, Bundy A, Lance E, Darland D, Casperson S, Roemmich J. Postnatal exercise protects offspring from high-fat diet-induced reductions in subcutaneous adipocyte beiging in C57Bl6/J mice. J Nutr Biochem. 2022;99:108853 pubmed publisher
Gao Y, Liu Y, Liu Y, Peng Y, Yuan B, Fu Y, et al. UHRF1 promotes androgen receptor-regulated CDC6 transcription and anti-androgen receptor drug resistance in prostate cancer through KDM4C-Mediated chromatin modifications. Cancer Lett. 2021;520:172-183 pubmed publisher
Ko J, Mills T, Huang J, Chen N, Mertens T, Collum S, et al. Transforming growth factor β1 alters the 3'-UTR of mRNA to promote lung fibrosis. J Biol Chem. 2019;294:15781-15794 pubmed publisher
Kalainayakan S, Ghosh P, Dey S, FitzGerald K, Sohoni S, Konduri P, et al. Cyclopamine tartrate, a modulator of hedgehog signaling and mitochondrial respiration, effectively arrests lung tumor growth and progression. Sci Rep. 2019;9:1405 pubmed publisher
Wu M, Cheng H, Yeh T, Li Y, Chen T, Sit W, et al. KDM4B is a coactivator of c-Jun and involved in gastric carcinogenesis. Cell Death Dis. 2019;10:68 pubmed publisher
Bao L, Chen Y, Lai H, Wu S, Wang J, Hatanpaa K, et al. Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration. Nucleic Acids Res. 2018;46:6576-6591 pubmed publisher
Xu M, Moresco J, Chang M, Mukim A, Smith D, Diedrich J, et al. SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy. PLoS Pathog. 2018;14:e1007071 pubmed publisher
Cameron A, Veeriah S, Marshall J, Murray E, Larijani B, Parker P. Uncoupling TORC2 from AGC kinases inhibits tumour growth. Oncotarget. 2017;8:84685-84696 pubmed publisher
Liu W, Yang H, Hsu C, Wang C, Wang T, Kao J, et al. Pegylated IFN-α suppresses hepatitis C virus by promoting the DAPK-mTOR pathway. Proc Natl Acad Sci U S A. 2016;113:14799-14804 pubmed publisher
Tsai J, Chao C, Lin L. Cadmium Activates Multiple Signaling Pathways That Coordinately Stimulate Akt Activity to Enhance c-Myc mRNA Stability. PLoS ONE. 2016;11:e0147011 pubmed publisher
Qiu M, Fan Q, Zhu Z, Kwan S, Chen L, Chen J, et al. KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1. Oncotarget. 2015;6:31702-20 pubmed publisher
Kusch A, Schmidt M, Gürgen D, Postpieszala D, Catar R, Hegner B, et al. 17ß-Estradiol regulates mTORC2 sensitivity to rapamycin in adaptive cardiac remodeling. PLoS ONE. 2015;10:e0123385 pubmed publisher
product information
master code :
NBP1-49600
SKU :
NBP1-49600
product name :
Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody - BSA Free from Novus is a rabbit polyclonal antibody to Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C. This antibody reacts with human,mouse. The Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody - BSA Free has been validated for the following applications: Knockdown Validated,Chemotaxis,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Chromatin Immunoprecipitation,Immunohistochemistry,Simple Western,Chromatin Immunoprecipitation (ChIP).
target :
Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A partial recombinant protein made to an internal region of the human JMJD2C protein (within residues 450-600). [Swiss-Prot Q9H3R0]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse
gene symbol :
KDM4C
Antibody validation :
Knockout/Knockdown
accessionNumbers :
Q9H3R0, Q8VCD7
applications :
Knockdown Validated,Chemotaxis,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Chromatin Immunoprecipitation,Immunohistochemistry,Simple Western,Chromatin Immunoprecipitation (ChIP)
USD :
399 USD
alt names :
EC 1.14.11, EC 1.14.11.-, GASC-1 protein, GASC1JmjC domain-containing histone demethylation protein 3C, Gene amplified in squamous cell carcinoma 1 protein, JHDM3C, JMJD2CbA146B14.1, jumonji domain containing 2C, Jumonji domain-containing protein 2C, KIAA0780FLJ25949, lysine (K)-specific demethylase 4C, lysine-specific demethylase 4C
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.