Pyruvate Carboxylase Antibody - BSA Free | Novus Biologicals NBP1-49536 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Pyruvate Carboxylase Antibody - BSA Free

catalog :

NBP1-49536

quantity :

0.1 ml (also 0.025 ml)

price :

409 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

mAb16

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 26

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; loading ...; fig s6c	Leone R, Zhao L, Englert J, Sun I, Oh M, Sun I, et al. Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion. Science. 2019;366:1013-1021 pubmed publisher
	Cai X, Ng C, Jones O, Fung T, Ryu K, Li D, et al. Lactate activates the mitochondrial electron transport chain independently of its metabolism. Mol Cell. 2023;83:3904-3920.e7 pubmed publisher
	Kershberg L, Banerjee A, Kaeser P. Protein composition of axonal dopamine release sites in the striatum. elife. 2022;11: pubmed publisher
	Guo X, Jiang X, Chen K, Liang Q, Zhang S, Zheng J, et al. The Role of Palmitoleic Acid in Regulating Hepatic Gluconeogenesis through SIRT3 in Obese Mice. Nutrients. 2022;14: pubmed publisher
	Schwörer S, Pavlova N, Cimino F, King B, Cai X, Sizemore G, et al. Fibroblast pyruvate carboxylase is required for collagen production in the tumour microenvironment. Nat Metab. 2021;3:1484-1499 pubmed publisher
	Chung C, Singh K, Kotiadis V, Valdebenito G, Ahn J, Topley E, et al. Constitutive activation of the PI3K-Akt-mTORC1 pathway sustains the m.3243 A > G mtDNA mutation. Nat Commun. 2021;12:6409 pubmed publisher
	Igelmann S, Lessard F, Uchenunu O, Bouchard J, Fernandez Ruiz A, Rowell M, et al. A hydride transfer complex reprograms NAD metabolism and bypasses senescence. Mol Cell. 2021;81:3848-3865.e19 pubmed publisher
	Shankar T, Ramadurai D, Steinhorst K, Sommakia S, Badolia R, Thodou Krokidi A, et al. Cardiac-specific deletion of voltage dependent anion channel 2 leads to dilated cardiomyopathy by altering calcium homeostasis. Nat Commun. 2021;12:4583 pubmed publisher
	Calvete O, Reyes J, Benitez J. Case Report: CMV Infection and Same Mechanism-Originated Intestinal Inflammation Compatible With Bowel/Crohn's Disease Is Suggested in ATP4A Mutated-Driven Gastric Neuroendocrine Tumors. Front Med (Lausanne). 2021;8:553110 pubmed publisher
	Song X, Liu J, Kuang F, Chen X, Zeh H, Kang R, et al. PDK4 dictates metabolic resistance to ferroptosis by suppressing pyruvate oxidation and fatty acid synthesis. Cell Rep. 2021;34:108767 pubmed publisher
	Carballo Carbajal I, Laguna A, Romero Gimenez J, Cuadros T, Bove J, Martinez Vicente M, et al. Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson's disease pathogenesis. Nat Commun. 2019;10:973 pubmed publisher
	Rattanapornsompong K, Ngamkham J, Chavalit T, Jitrapakdee S. Generation of Human Pyruvate Carboxylase Knockout Cell Lines Using Retrovirus Expressing Short Hairpin RNA and CRISPR-Cas9 as Models to Study Its Metabolic Role in Cancer Research. Methods Mol Biol. 2019;1916:273-288 pubmed publisher
	Toledo M, Batista Gonzalez A, Merheb E, Aoun M, Tarabra E, Feng D, et al. Autophagy Regulates the Liver Clock and Glucose Metabolism by Degrading CRY1. Cell Metab. 2018;28:268-281.e4 pubmed publisher
	Li X, Han G, Li X, Kan Q, Fan Z, Li Y, et al. Mitochondrial pyruvate carrier function determines cell stemness and metabolic reprogramming in cancer cells. Oncotarget. 2017;8:46363-46380 pubmed publisher
	Seale L, Gilman C, Hashimoto A, Ogawa Wong A, Berry M. Diet-induced obesity in the selenocysteine lyase knockout mouse. Antioxid Redox Signal. 2015;23:761-74 pubmed publisher
	Moritz A, Foster J, Gorentla B, Mazei Robison M, Yang J, Sitte H, et al. Phosphorylation of dopamine transporter serine 7 modulates cocaine analog binding. J Biol Chem. 2013;288:20-32 pubmed publisher
	Foster J, Yang J, Moritz A, Challasivakanaka S, Smith M, Holy M, et al. Dopamine transporter phosphorylation site threonine 53 regulates substrate reuptake and amphetamine-stimulated efflux. J Biol Chem. 2012;287:29702-12 pubmed publisher
	Foster J, Vaughan R. Palmitoylation controls dopamine transporter kinetics, degradation, and protein kinase C-dependent regulation. J Biol Chem. 2011;286:5175-86 pubmed publisher
	Cervinski M, Foster J, Vaughan R. Syntaxin 1A regulates dopamine transporter activity, phosphorylation and surface expression. Neuroscience. 2010;170:408-16 pubmed publisher
	Perry M, Leinninger G, Chen R, Luderman K, Yang H, Gnegy M, et al. Leptin promotes dopamine transporter and tyrosine hydroxylase activity in the nucleus accumbens of Sprague-Dawley rats. J Neurochem. 2010;114:666-74 pubmed publisher
	Furman C, Chen R, Guptaroy B, Zhang M, Holz R, Gnegy M. Dopamine and amphetamine rapidly increase dopamine transporter trafficking to the surface: live-cell imaging using total internal reflection fluorescence microscopy. J Neurosci. 2009;29:3328-36 pubmed publisher
	Gorentla B, Moritz A, Foster J, Vaughan R. Proline-directed phosphorylation of the dopamine transporter N-terminal domain. Biochemistry. 2009;48:1067-76 pubmed publisher
	Chen R, Zhang M, Park S, Gnegy M. C57BL/6J mice show greater amphetamine-induced locomotor activation and dopamine efflux in the striatum than 129S2/SvHsd mice. Pharmacol Biochem Behav. 2007;87:158-63 pubmed
	Johnson L, Furman C, Zhang M, Guptaroy B, Gnegy M. Rapid delivery of the dopamine transporter to the plasmalemmal membrane upon amphetamine stimulation. Neuropharmacology. 2005;49:750-8 pubmed
	Johnson L, Guptaroy B, Lund D, Shamban S, Gnegy M. Regulation of amphetamine-stimulated dopamine efflux by protein kinase C beta. J Biol Chem. 2005;280:10914-9 pubmed
	Gaffaney J, Vaughan R. Uptake inhibitors but not substrates induce protease resistance in extracellular loop two of the dopamine transporter. Mol Pharmacol. 2004;65:692-701 pubmed

product information

master code :

NBP1-49536

SKU :

NBP1-49536

product name :

Pyruvate Carboxylase Antibody - BSA Free

unit size :

0.1 ml (also 0.025 ml)

description :

The Pyruvate Carboxylase Antibody - BSA Free from Novus is a rabbit polyclonal antibody to Pyruvate Carboxylase. This antibody reacts with human,mouse,rat. The Pyruvate Carboxylase Antibody - BSA Free has been validated for the following applications: Western Blot,Immunofluorescence,Immunocytochemistry,IF/IHC,Immunohistochemistry,Immunohistochemistry-Paraffin,Knockdown Validated,Immunocytochemistry/ Immunofluorescence.

target :

Pyruvate Carboxylase

category :

Primary Antibodies

buffer :

PBS

clonality :

Polyclonal

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Partial recombinant protein made to an internal region of the human Pyruvate Carboxylase protein (within residues 930-1050). [Swiss-Prot P11498]

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human,Mouse,Rat

theoretical molecular weight :

126 kDa

gene symbol :

Antibody validation :

Biological Validation

accessionNumbers :

P11498, Q05920

applications :

Western Blot,Immunofluorescence,Immunocytochemistry,IF/IHC,Immunohistochemistry,Immunohistochemistry-Paraffin,Knockdown Validated,Immunocytochemistry/ Immunofluorescence

USD :

409 USD

alt names :

EC 6.4.1, EC 6.4.1.1, PCBPyruvic carboxylase, pyruvate carboxylase, pyruvate carboxylase, mitochondrial

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage