product summary
Loading...
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
CD8 Antibody (53-6.7) - BSA Free
catalog :
NBP1-49045
quantity :
0.5 mg (also 0.1 mg)
price :
429 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
53-6.7
reactivity :
human, mouse, rat
application :
immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 51
Reference
Zhou J, Wang H, Shu T, Wang J, Yang W, Li J, et al. Myeloid-intrinsic cell cycle-related kinase drives immunosuppression to promote tumorigenesis. iScience. 2023;26:107626 pubmed publisher
Won S, Lee C, Bae S, Lee J, Choi D, Kim M, et al. Mass-produced gram-negative bacterial outer membrane vesicles activate cancer antigen-specific stem-like CD8+ T cells which enables an effective combination immunotherapy with anti-PD-1. J Extracell Vesicles. 2023;12:e12357 pubmed publisher
Son S, Nam J, Kim A, Ahn J, Park K, Phoo M, et al. Induction of T-helper-17-cell-mediated anti-tumour immunity by pathogen-mimicking polymer nanoparticles. Nat Biomed Eng. 2023;7:72-84 pubmed publisher
Salman S, Meyers D, Wicks E, Lee S, Datan E, Thomas A, et al. HIF inhibitor 32-134D eradicates murine hepatocellular carcinoma in combination with anti-PD1 therapy. J Clin Invest. 2022;132: pubmed publisher
Reyes A, Goldusky J, Bhimalli P, Marzo A, Schneider J. Tracking fluorescently labeled IL-15 and anti-PD-1 in the tumor microenvironment and draining lymph nodes. J Immunol Methods. 2022;505:113253 pubmed publisher
Jie X, Chen Y, Zhao Y, Yang X, Xu Y, Wang J, et al. Targeting KDM4C enhances CD8+ T cell mediated antitumor immunity by activating chemokine CXCL10 transcription in lung cancer. J Immunother Cancer. 2022;10: pubmed publisher
Zhang Z, Na H, Gan Q, Tao Q, Alekseyev Y, Hu J, et al. Monomeric C-reactive protein via endothelial CD31 for neurovascular inflammation in an ApoE genotype-dependent pattern: A risk factor for Alzheimer's disease?. Aging Cell. 2021;20:e13501 pubmed publisher
Yang W, Feng Y, Zhou J, Cheung O, Cao J, Wang J, et al. A selective HDAC8 inhibitor potentiates antitumor immunity and efficacy of immune checkpoint blockade in hepatocellular carcinoma. Sci Transl Med. 2021;13: pubmed publisher
Block M, Dietz A, Gustafson M, Kalli K, Erskine C, Youssef B, et al. Th17-inducing autologous dendritic cell vaccination promotes antigen-specific cellular and humoral immunity in ovarian cancer patients. Nat Commun. 2020;11:5173 pubmed publisher
Hoover A, Hufnagel D, HARRIS W, Bullock K, Glass E, Liu E, et al. Increased canonical NF-kappaB signaling specifically in macrophages is sufficient to limit tumor progression in syngeneic murine models of ovarian cancer. BMC Cancer. 2020;20:970 pubmed publisher
Samanta D, Huang T, Shah R, Yang Y, Pan F, Semenza G. BIRC2 Expression Impairs Anti-Cancer Immunity and Immunotherapy Efficacy. Cell Rep. 2020;32:108073 pubmed publisher
Cai E, Ishikawa Y, Zhang W, Leite N, Li J, Hou S, et al. Genome-scale in vivo CRISPR screen identifies RNLS as a target for beta cell protection in type 1 diabetes. Nat Metab. 2020;2:934-945 pubmed publisher
Dee R, Bai X, Mack C, Taylor J. Molecular Regulation of the RhoGAP GRAF3 and Its Capacity to Limit Blood Pressure In Vivo. Cells. 2020;9: pubmed publisher
Krohn L, Ozturk T, Vanderperre B, Ouled Amar Bencheikh B, Ruskey J, Laurent S, et al. Genetic, Structural, and Functional Evidence Link TMEM175 to Synucleinopathies. Ann Neurol. 2020;87:139-153 pubmed publisher
Westrich J, Vermeer D, Silva A, Bonney S, Berger J, Cicchini L, et al. CXCL14 suppresses human papillomavirus-associated head and neck cancer through antigen-specific CD8+ T-cell responses by upregulating MHC-I expression. Oncogene. 2019;: pubmed publisher
Zeng Y, Bhagyashree B, Zhao W, Nguyen T, Segatori L. Hysteretic Genetic Circuit for Detection of Proteasomal Degradation in Mammalian Cells. ACS Synth Biol. 2019;8:2025-2035 pubmed publisher
DeAngelis M, Johnson R. Dissection of the Drosophila Pupal Retina for Immunohistochemistry, Western Analysis, and RNA Isolation. J Vis Exp. 2019;: pubmed publisher
Zhou X, Kinlough C, Hughey R, Jin M, Inoue H, Etling E, et al. Sialylation of MUC4β N-glycans by ST6GAL1 orchestrates human airway epithelial cell differentiation associated with type-2 inflammation. JCI Insight. 2019;4: pubmed publisher
Muta Y, Tanaka T, Hamaguchi Y, Hamanoue N, Motonaga R, Tanabe M, et al. Selective androgen receptor modulator, S42 has anabolic and anti-catabolic effects on cultured myotubes. Biochem Biophys Rep. 2019;17:177-181 pubmed publisher
Patron L, Nagatomo K, Eves D, Imad M, Young K, Torvund M, et al. Cul4 ubiquitin ligase cofactor DCAF12 promotes neurotransmitter release and homeostatic plasticity. J Cell Biol. 2019;218:993-1010 pubmed publisher
Chakrabarti J, Holokai L, Syu L, Steele N, Chang J, Wang J, et al. Hedgehog signaling induces PD-L1 expression and tumor cell proliferation in gastric cancer. Oncotarget. 2018;9:37439-37457 pubmed publisher
Inoue H, Hattori T, Zhou X, Etling E, Modena B, Trudeau J, et al. Dysfunctional ErbB2, an EGF receptor family member, hinders repair of airway epithelial cells from asthmatic patients. J Allergy Clin Immunol. 2019;143:2075-2085.e10 pubmed publisher
Fazia T, Pastorino R, Notartomaso S, Busceti C, Imbriglio T, Cannella M, et al. Acid sensing ion channel 2: A new potential player in the pathophysiology of multiple sclerosis. Eur J Neurosci. 2019;49:1233-1243 pubmed publisher
Heine M, Fischer A, Schlein C, Jung C, Straub L, Gottschling K, et al. Lipolysis Triggers a Systemic Insulin Response Essential for Efficient Energy Replenishment of Activated Brown Adipose Tissue in Mice. Cell Metab. 2018;: pubmed publisher
Hashimoto T, Kim G, Tunin R, Adesiyun T, Hsu S, Nakagawa R, et al. Acute Enhancement of Cardiac Function by Phosphodiesterase Type 1 Inhibition: A Translational Study in the Dog and Rabbit. Circulation. 2018;: pubmed publisher
Ramos Lewis W, Lafever K, Page McCaw A. A scar-like lesion is apparent in basement membrane after wound repair in vivo. Matrix Biol. 2018;74:101-120 pubmed publisher
Sullivan C, Gotthard I, Wyatt E, Bongu S, Mohan V, Weinberg R, et al. Perineuronal Net Protein Neurocan Inhibits NCAM/EphA3 Repellent Signaling in GABAergic Interneurons. Sci Rep. 2018;8:6143 pubmed publisher
Hain A, Krämer M, Linka R, Nakhaei Rad S, Ahmadian M, Häussinger D, et al. IL-2 Inducible Kinase ITK is Critical for HIV-1 Infection of Jurkat T-cells. Sci Rep. 2018;8:3217 pubmed publisher
Samanta D, Park Y, Ni X, Li H, Zahnow C, Gabrielson E, et al. Chemotherapy induces enrichment of CD47+/CD73+/PDL1+ immune evasive triple-negative breast cancer cells. Proc Natl Acad Sci U S A. 2018;115:E1239-E1248 pubmed publisher
Bushnell H, Feiler C, Ketosugbo K, Hellerman M, Nazzaro V, Johnson R. JNK is antagonized to ensure the correct number of interommatidial cells pattern the Drosophila retina. Dev Biol. 2018;433:94-107 pubmed publisher
Sierra R, Trillo Tinoco J, Mohamed E, Yu L, Achyut B, Arbab A, et al. Anti-Jagged Immunotherapy Inhibits MDSCs and Overcomes Tumor-Induced Tolerance. Cancer Res. 2017;77:5628-5638 pubmed publisher
Hope K, Ledoux M, Reiter L. Glial overexpression of Dube3a causes seizures and synaptic impairments in Drosophila concomitant with down regulation of the Na+/K+ pump ATP?. Neurobiol Dis. 2017;108:238-248 pubmed publisher
Grosse S, Penaud Budloo M, Herrmann A, Börner K, Fakhiri J, Laketa V, et al. Relevance of Assembly-Activating Protein for Adeno-associated Virus Vector Production and Capsid Protein Stability in Mammalian and Insect Cells. J Virol. 2017;91: pubmed publisher
Ma S, Deng W, Liu J, Mao L, Yu G, Bu L, et al. Blockade of adenosine A2A receptor enhances CD8+ T cells response and decreases regulatory T cells in head and neck squamous cell carcinoma. Mol Cancer. 2017;16:99 pubmed publisher
Cohen N, Shani O, Raz Y, Sharon Y, Hoffman D, Abramovitz L, et al. Fibroblasts drive an immunosuppressive and growth-promoting microenvironment in breast cancer via secretion of Chitinase 3-like 1. Oncogene. 2017;36:4457-4468 pubmed publisher
Yi H, Zhang Q, Brooks E, Yang C, Thurberg B, Kishnani P, et al. Systemic Correction of Murine Glycogen Storage Disease Type IV by an AAV-Mediated Gene Therapy. Hum Gene Ther. 2017;28:286-294 pubmed publisher
Li A, Wu Y, Tang F, Li W, Feng X, Yao Z. In Vivo Magnetic Resonance Imaging of CD8+ T Lymphocytes Recruiting to Glioblastoma in Mice. Cancer Biother Radiopharm. 2016;31:317-323 pubmed
Bell R, Hauser S, Rodd Z, Liang T, Sari Y, McClintick J, et al. A Genetic Animal Model of Alcoholism for Screening Medications to Treat Addiction. Int Rev Neurobiol. 2016;126:179-261 pubmed publisher
Rusconi F, Grillo B, Ponzoni L, Bassani S, Toffolo E, Paganini L, et al. LSD1 modulates stress-evoked transcription of immediate early genes and emotional behavior. Proc Natl Acad Sci U S A. 2016;113:3651-6 pubmed publisher
Urraca N, Memon R, El Iyachi I, Goorha S, Valdez C, Tran Q, et al. Characterization of neurons from immortalized dental pulp stem cells for the study of neurogenetic disorders. Stem Cell Res. 2015;15:722-730 pubmed publisher
Bader C, Shandala T, Ng Y, Johnson I, Brooks D. Atg9 is required for intraluminal vesicles in amphisomes and autolysosomes. Biol Open. 2015;4:1345-55 pubmed publisher
Hijazi A, Guan H, Cernea M, Yang K. Prenatal exposure to bisphenol A disrupts mouse fetal lung development. FASEB J. 2015;29:4968-77 pubmed publisher
DeBenedictis B, Guan H, Yang K. Prenatal Exposure to Bisphenol A Disrupts Mouse Fetal Liver Maturation in a Sex-Specific Manner. J Cell Biochem. 2016;117:344-50 pubmed publisher
Grillon E, Farion R, Reuveni M, Glidle A, Rémy C, Coles J. Spatial profiles of markers of glycolysis, mitochondria, and proton pumps in a rat glioma suggest coordinated programming for proliferation. BMC Res Notes. 2015;8:207 pubmed publisher
Rao P, Bell R, Engleman E, Sari Y. Targeting glutamate uptake to treat alcohol use disorders. Front Neurosci. 2015;9:144 pubmed publisher
Obis T, Besalduch N, Hurtado E, Nadal L, Santafe M, Garcia N, et al. The novel protein kinase C epsilon isoform at the adult neuromuscular synapse: location, regulation by synaptic activity-dependent muscle contraction through TrkB signaling and coupling to ACh release. Mol Brain. 2015;8:8 pubmed publisher
Rusconi F, Paganini L, Braida D, Ponzoni L, Toffolo E, Maroli A, et al. LSD1 Neurospecific Alternative Splicing Controls Neuronal Excitability in Mouse Models of Epilepsy. Cereb Cortex. 2015;25:2729-40 pubmed publisher
Fazio F, Zappulla C, Notartomaso S, Busceti C, Bessede A, Scarselli P, et al. Cinnabarinic acid, an endogenous agonist of type-4 metabotropic glutamate receptor, suppresses experimental autoimmune encephalomyelitis in mice. Neuropharmacology. 2014;81:237-43 pubmed publisher
Kheradmand T, Wang S, Gibly R, Zhang X, Holland S, Tasch J, et al. Permanent protection of PLG scaffold transplanted allogeneic islet grafts in diabetic mice treated with ECDI-fixed donor splenocyte infusions. Biomaterials. 2011;32:4517-24 pubmed publisher
Bankoti J, Burnett A, Navarro S, Miller A, Rase B, Shepherd D. Effects of TCDD on the fate of naive dendritic cells. Toxicol Sci. 2010;115:422-34 pubmed publisher
McLellan A, Kapp M, Eggert A, Linden C, Bommhardt U, Brocker E, et al. Anatomic location and T-cell stimulatory functions of mouse dendritic cell subsets defined by CD4 and CD8 expression. Blood. 2002;99:2084-93 pubmed
product information
master code :
NBP1-49045
SKU :
NBP1-49045
product name :
CD8 Antibody (53-6.7) - BSA Free
unit size :
0.5 mg (also 0.1 mg)
description :
The CD8 Antibody (53-6.7) - BSA Free from Novus is a rat monoclonal antibody to CD8. This antibody reacts with human,mouse,rat. The CD8 Antibody (53-6.7) - BSA Free has been validated for the following applications: Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,IF/IHC,Flow Cytometry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunoprecipitation,Cell depletion,Inhibition of T Cell Function,CyTOF-ready.
target :
CD8
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
53-6.7
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rat
immunogen :
CD8 Antibody (53-6.7) was developed against mouse thymus or spleen.
isotype :
IgG2a Kappa
purity :
Protein A or G purified
species :
Human,Mouse,Rat
theoretical molecular weight :
27 kDa
gene symbol :
CD8A
applications :
Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,IF/IHC,Flow Cytometry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunoprecipitation,Cell depletion,Inhibition of T Cell Function,CyTOF-ready
USD :
429 USD
alt names :
53-6.7, 53-6.7 CD8, 53-6.7 CD8 Alpha, 53-6.7 CD8 Aplha, 53-6.7 Clone, CD_antigen: CD8a, CD8, CD8 antigen, alpha polypeptide (p32), CD8A, CD8a molecule, Cytotoxic T cell marker, Cytotoxic T lymphocyte marker, LEU2, Leu2 T-lymphocyte antigen, MAL, OKT8 T-cell antigen, p32, T cell co-receptor, T cell marker, T8 T-cell antigen, T-cell antigen Leu2, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.