CCR2 Antibody - BSA Free | Novus Biologicals NBP1-48337 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

CCR2 Antibody - BSA Free

catalog :

NBP1-48337

quantity :

0.1 ml (also 0.025 ml)

price :

439 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

98A1071

reactivity :

human, mouse, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 44

Reference
Li L, Liu Y, Hu W, Yang J, Ma S, Tian Z, et al. Peripheral CCL2 induces inflammatory pain via regulation of Ih currents in small diameter DRG neurons. Front Mol Neurosci. 2023;16:1144614 pubmed publisher
Soma K, Hitomi S, Hayashi Y, Soma C, Otsuji J, Shibuta I, et al. Neonatal Injury Modulates Incisional Pain Sensitivity in Adulthood: An Animal Study. Neuroscience. 2023;519:60-72 pubmed publisher
Tanaka T, Okuda H, Isonishi A, Terada Y, Kitabatake M, Shinjo T, et al. Dermal macrophages set pain sensitivity by modulating the amount of tissue NGF through an SNX25-Nrf2 pathway. Nat Immunol. 2023;24:439-451 pubmed publisher
Mao Y, Lv X, Xu W, Ying Y, Qin Z, Liao H, et al. Identification and validation of candidate genes dysregulated in alveolar macrophages of acute respiratory distress syndrome. Peerj. 2021;9:e12312 pubmed publisher
Hummitzsch L, Zitta K, Fritze L, Monnens J, Vollertsen P, Lindner M, et al. Effects of remote ischemic preconditioning (RIPC) and chronic remote ischemic preconditioning (cRIPC) on levels of plasma cytokines, cell surface characteristics of monocytes and in-vitro angiogenesis: a pilot study. Basic Res Cardiol. 2021;116:60 pubmed publisher
Fang W, Sofia Acevedo D, Smart C, Zinda B, Alissa N, Warren K, et al. Expression of CCL2/CCR2 signaling proteins in breast carcinoma cells is associated with invasive progression. Sci Rep. 2021;11:8708 pubmed publisher
Korimová A, Dubovy P. N-Formylated Peptide Induces Increased Expression of Both Formyl Peptide Receptor 2 (Fpr2) and Toll-Like Receptor 9 (TLR9) in Schwannoma Cells-An In Vitro Model for Early Inflammatory Profiling of Schwann Cells. Cells. 2020;9: pubmed publisher
Bayer Alinca S, Saglam E, Zengin Celik T, Hacisalihoglu P, Doğan M. Is low level laser therapy or ozone therapy more effective for bone healing? Understanding the mechanisms of HIF-1α, RANKL and OPG. Biotech Histochem. 2020;:1-8 pubmed publisher
Hirayama H, Sakumoto R, Koyama K, Yasuhara T, Hasegawa T, Inaba R, et al. Expression of C-C motif chemokines and their receptors in bovine placentomes at spontaneous and induced parturition. J Reprod Dev. 2020;66:49-55 pubmed publisher
Lee Y, Chan Y, Hsieh S, Lew W, Feng S. Comparing the Osteogenic Potentials and Bone Regeneration Capacities of Bone Marrow and Dental Pulp Mesenchymal Stem Cells in a Rabbit Calvarial Bone Defect Model. Int J Mol Sci. 2019;20: pubmed publisher
Wang X, Cao Y, Liu Z, Wang Z, Chu X, Wang L, et al. Alveolar Bone Density Reduction in Rats Caused by Unilateral Nasal Obstruction. Balkan Med J. 2019;36:311-319 pubmed publisher
Gegen T, Zhu Y, Sun Q, Hou B. Role of interleukin-33 in the clinical pathogenesis of chronic apical periodontitis. J Int Med Res. 2019;47:3332-3343 pubmed publisher
Rojo J, Jaworski J, PELUFFO M. Direct role of the C-C motif chemokine receptor 2/monocyte chemoattractant protein 1 system in the feline cumulus oocyte complex†. Biol Reprod. 2019;100:1046-1056 pubmed publisher
Kwon J, Lee S, Na H, Jung K, Choi J, Cho K, et al. Kartogenin inhibits pain behavior, chondrocyte inflammation, and attenuates osteoarthritis progression in mice through induction of IL-10. Sci Rep. 2018;8:13832 pubmed publisher
Li D, Wang C, Li Z, Wang H, He J, Zhu J, et al. Nano-sized Al2O3 particle-induced autophagy reduces osteolysis in aseptic loosening of total hip arthroplasty by negative feedback regulation of RANKL expression in fibroblasts. Cell Death Dis. 2018;9:840 pubmed publisher
El Kholy K, Freire M, Chen T, Van Dyke T. Resolvin E1 Promotes Bone Preservation Under Inflammatory Conditions. Front Immunol. 2018;9:1300 pubmed publisher
Nozawa S, Inubushi T, Irie F, Takigami I, Matsumoto K, Shimizu K, et al. Osteoblastic heparan sulfate regulates osteoprotegerin function and bone mass. JCI Insight. 2018;3: pubmed publisher
Scimeca M, Salustri A, Bonanno E, Nardozi D, Rao C, Piccirilli E, et al. Impairment of PTX3 expression in osteoblasts: a key element for osteoporosis. Cell Death Dis. 2017;8:e3125 pubmed publisher
Sakumoto R, Hayashi K, Fujii S, Kanahara H, Hosoe M, Furusawa T, et al. Possible Roles of CC- and CXC-Chemokines in Regulating Bovine Endometrial Function during Early Pregnancy. Int J Mol Sci. 2017;18: pubmed publisher
Stanisławowski M, Wisniewski P, Guzek M, Wierzbicki P, Adrych K, Smoczynski M, et al. Influence of receptor activator of nuclear factor kappa B ligand, osteoprotegerin and interleukin-33 on bone metabolism in patients with long-standing ulcerative colitis. J Crohns Colitis. 2014;8:802-10 pubmed publisher
Larson S, Zhang X, Dumpit R, Coleman I, Lakely B, Roudier M, et al. Characterization of osteoblastic and osteolytic proteins in prostate cancer bone metastases. Prostate. 2013;73:932-40 pubmed publisher
Boumans M, Thurlings R, Yeo L, Scheel Toellner D, Vos K, Gerlag D, et al. Rituximab abrogates joint destruction in rheumatoid arthritis by inhibiting osteoclastogenesis. Ann Rheum Dis. 2012;71:108-13 pubmed publisher
Witasp A, Carrero J, Hammarqvist F, Qureshi A, Heimburger O, Schalling M, et al. Expression of osteoprotegerin in human fat tissue; implications for chronic kidney disease. Eur J Clin Invest. 2011;41:498-506 pubmed publisher
Tomlins C, Storey A. Cutaneous HPV5 E6 causes increased expression of Osteoprotegerin and Interleukin 6 which contribute to evasion of UV-induced apoptosis. Carcinogenesis. 2010;31:2155-64 pubmed publisher
Pohjolainen V, Taskinen P, Soini Y, Rysa J, Ilves M, Juvonen T, et al. Noncollagenous bone matrix proteins as a part of calcific aortic valve disease regulation. Hum Pathol. 2008;39:1695-701 pubmed publisher
Vandooren B, Cantaert T, Noordenbos T, Tak P, Baeten D. The abundant synovial expression of the RANK/RANKL/Osteoprotegerin system in peripheral spondylarthritis is partially disconnected from inflammation. Arthritis Rheum. 2008;58:718-29 pubmed publisher
Waterman E, Cross N, Lippitt J, Cross S, Rehman I, Holen I, et al. The antibody MAB8051 directed against osteoprotegerin detects carbonic anhydrase II: implications for association studies with human cancers. Int J Cancer. 2007;121:1958-66 pubmed
Pettit A, Walsh N, Manning C, Goldring S, Gravallese E. RANKL protein is expressed at the pannus-bone interface at sites of articular bone erosion in rheumatoid arthritis. Rheumatology (Oxford). 2006;45:1068-76 pubmed
Sandra F, Hendarmin L, Nakamura S. Osteoprotegerin (OPG) binds with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL): suppression of TRAIL-induced apoptosis in ameloblastomas. Oral Oncol. 2006;42:415-20 pubmed
Pettersen I, Bakkelund W, Smedsrød B, Sveinbjørnsson B. Osteoprotegerin is expressed in colon carcinoma cells. Anticancer Res. 2005;25:3809-16 pubmed
Gaudio A, Lasco A, Morabito N, Atteritano M, Vergara C, Catalano A, et al. Hepatic osteodystrophy: does the osteoprotegerin/receptor activator of nuclear factor-kB ligand system play a role?. J Endocrinol Invest. 2005;28:677-82 pubmed
Moschen A, Kaser A, Stadlmann S, Millonig G, Kaser S, Mühllechner P, et al. The RANKL/OPG system and bone mineral density in patients with chronic liver disease. J Hepatol. 2005;43:973-83 pubmed
Moran C, McCann M, Karan M, Norman P, Ketheesan N, Golledge J. Association of osteoprotegerin with human abdominal aortic aneurysm progression. Circulation. 2005;111:3119-25 pubmed
Sandra F, Hendarmin L, Kukita T, Nakao Y, Nakamura N, Nakamura S. Ameloblastoma induces osteoclastogenesis: a possible role of ameloblastoma in expanding in the bone. Oral Oncol. 2005;41:637-44 pubmed
Moschen A, Kaser A, Enrich B, Ludwiczek O, Gabriel M, Obrist P, et al. The RANKL/OPG system is activated in inflammatory bowel disease and relates to the state of bone loss. Gut. 2005;54:479-87 pubmed
Vidal K, Serrant P, Schlosser B, van den Broek P, Lorget F, Donnet Hughes A. Osteoprotegerin production by human intestinal epithelial cells: a potential regulator of mucosal immune responses. Am J Physiol Gastrointest Liver Physiol. 2004;287:G836-44 pubmed
Vidal K, van den Broek P, Lorget F, Donnet Hughes A. Osteoprotegerin in human milk: a potential role in the regulation of bone metabolism and immune development. Pediatr Res. 2004;55:1001-8 pubmed
Golledge J, McCann M, Mangan S, Lam A, Karan M. Osteoprotegerin and osteopontin are expressed at high concentrations within symptomatic carotid atherosclerosis. Stroke. 2004;35:1636-41 pubmed
Standal T, Seidel C, Hjertner Ø, Plesner T, Sanderson R, Waage A, et al. Osteoprotegerin is bound, internalized, and degraded by multiple myeloma cells. Blood. 2002;100:3002-7 pubmed
Komuro H, Olee T, Kuhn K, Quach J, Brinson D, Shikhman A, et al. The osteoprotegerin/receptor activator of nuclear factor kappaB/receptor activator of nuclear factor kappaB ligand system in cartilage. Arthritis Rheum. 2001;44:2768-76 pubmed
Fiumara P, Snell V, Li Y, Mukhopadhyay A, Younes M, Gillenwater A, et al. Functional expression of receptor activator of nuclear factor kappaB in Hodgkin disease cell lines. Blood. 2001;98:2784-90 pubmed
Pearse R, Sordillo E, Yaccoby S, Wong B, Liau D, Colman N, et al. Multiple myeloma disrupts the TRANCE/ osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression. Proc Natl Acad Sci U S A. 2001;98:11581-6 pubmed
Saika M, Inoue D, Kido S, Matsumoto T. 17beta-estradiol stimulates expression of osteoprotegerin by a mouse stromal cell line, ST-2, via estrogen receptor-alpha. Endocrinology. 2001;142:2205-12 pubmed
Kobayashi Y, Hashimoto F, Miyamoto H, Kanaoka K, Miyazaki Kawashita Y, Nakashima T, et al. Force-induced osteoclast apoptosis in vivo is accompanied by elevation in transforming growth factor beta and osteoprotegerin expression. J Bone Miner Res. 2000;15:1924-34 pubmed

product information

master code :

NBP1-48337

SKU :

NBP1-48337

product name :

CCR2 Antibody - BSA Free

unit size :

0.1 ml (also 0.025 ml)

description :

The CCR2 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to CCR2. This antibody reacts with bovine,feline,human,mouse,rat. The CCR2 Antibody - BSA Free has been validated for the following applications: IF/IHC,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Flow Cytometry.

target :

CCR2

category :

Primary Antibodies

buffer :

PBS

clonality :

Polyclonal

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Synthetic peptide made to an N-terminal portion of the human CCR2 protein (within residues 20-100). [Swiss-Prot# P41597]

isotype :

IgG

purity :

Immunogen affinity purified

species :

Bovine,Feline,Human,Mouse,Rat

gene symbol :

CCR2

accessionNumbers :

P41597

applications :

IF/IHC,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Flow Cytometry

USD :

439 USD

alt names :

C-C chemokine receptor type 2, C-C CKR-2, CC-CKR-2CKR2B, CCR-2, CCR2A, CCR2B, CD192, CD192 antigen, chemokine (C-C motif) receptor 2, CKR2, CKR2A, CMKBR2MGC111760, FLJ78302, MCP-1 receptor, MCP-1-RMGC103828, MGC168006, Monocyte chemoattractant protein 1 receptor, monocyte chemotactic protein 1 receptor

storage :

Store at -20C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage