product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Lactate Dehydrogenase A/LDHA Antibody - BSA Free
catalog :
NBP1-48336
quantity :
0.1 ml (also 0.025 ml)
price :
419 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, bovine
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 51
Reference
Schwab M, Dezfouli A, Khosravi M, Alkotub B, Bauer L, Birgani M, et al. The radiation- and chemo-sensitizing capacity of diclofenac can be predicted by a decreased lactate metabolism and stress response. Radiat Oncol. 2024;19:7 pubmed publisher
HU Z, Yu X, Ding R, Liu B, Gu C, Pan X, et al. Glycolysis drives STING signaling to facilitate dendritic cell antitumor function. J Clin Invest. 2023;133: pubmed publisher
Maucieri A, Townson D. Evaluating the impact of the hexosamine biosynthesis pathway and O-GlcNAcylation on glucose metabolism in bovine granulosa cells. Mol Cell Endocrinol. 2023;564:111863 pubmed publisher
Cappellesso F, Orban M, Shirgaonkar N, Berardi E, Serneels J, Neveu M, et al. Targeting the bicarbonate transporter SLC4A4 overcomes immunosuppression and immunotherapy resistance in pancreatic cancer. Nat Cancer. 2022;3:1464-1483 pubmed publisher
Nsiah N, Inman D. Destabilizing COXIV in Müller Glia Increases Retinal Glycolysis and Alters Scotopic Electroretinogram. Cells. 2022;11: pubmed publisher
Marwarha G, R xf8 sand x, Slagsvold K, H xf8 ydal M. GSK3β Inhibition Is the Molecular Pivot That Underlies the Mir-210-Induced Attenuation of Intrinsic Apoptosis Cascade during Hypoxia. Int J Mol Sci. 2022;23: pubmed publisher
Pappenhagen N, Yin E, Morgan A, Kiehlbauch C, Inman D. Stretch stress propels glutamine dependency and glycolysis in optic nerve head astrocytes. Front Neurosci. 2022;16:957034 pubmed publisher
Schwab M, Multhoff G. A Low Membrane Hsp70 Expression in Tumor Cells With Impaired Lactate Metabolism Mediates Radiosensitization by NVP-AUY922. Front Oncol. 2022;12:861266 pubmed publisher
Marwarha G, Røsand Ø, Scrimgeour N, Slagsvold K, Høydal M. miR-210 Regulates Apoptotic Cell Death during Cellular Hypoxia and Reoxygenation in a Diametrically Opposite Manner. Biomedicines. 2021;10: pubmed publisher
Schwab M, Thunborg K, Azimzadeh O, von Toerne C, Werner C, Shevtsov M, et al. Targeting Cancer Metabolism Breaks Radioresistance by Impairing the Stress Response. Cancers (Basel). 2021;13: pubmed publisher
Shen W, Lee S, Mathai A, Zhang R, Du J, Yam M, et al. Effect of selectively knocking down key metabolic genes in Müller glia on photoreceptor health. Glia. 2021;69:1966-1986 pubmed publisher
Pinto I, Soares R, Mäkinen M, Chotteau V, Russom A. Multiplexed Microfluidic Cartridge for At-Line Protein Monitoring in Mammalian Cell Culture Processes for Biopharmaceutical Production. ACS Sens. 2021;6:842-851 pubmed publisher
Osis G, Traylor A, Black L, Spangler D, George J, Zarjou A, et al. Expression of lactate dehydrogenase A and B isoforms in the mouse kidney. Am J Physiol Renal Physiol. 2021;320:F706-F718 pubmed publisher
Rossi A, Galla L, Gomiero C, Zentilin L, Giacca M, Giorgio V, et al. Calcium Signaling and Mitochondrial Function in Presenilin 2 Knock-Out Mice: Looking for Any Loss-of-Function Phenotype Related to Alzheimer's Disease. Cells. 2021;10: pubmed publisher
Knowles H. Distinct roles for the hypoxia-inducible transcription factors HIF-1α and HIF-2α in human osteoclast formation and function. Sci Rep. 2020;10:21072 pubmed publisher
Dang D, Buhler J, Thornton K, Legako J, Matarneh S. Myosin heavy chain isoform and metabolic profile differ in beef steaks varying in tenderness. Meat Sci. 2020;170:108266 pubmed publisher
Ulman A, Skrzypek K, Konieczny P, Mussolino C, Cathomen T, Majka M. Genome Editing of the SNAI1 Gene in Rhabdomyosarcoma: A Novel Model for Studies of Its Role. Cells. 2020;9: pubmed publisher
Pino Barrio M, Giménez Y, Villanueva M, Hildenbeutel M, Sánchez Domínguez R, Rodriguez Perales S, et al. TALEN mediated gene editing in a mouse model of Fanconi anemia. Sci Rep. 2020;10:6997 pubmed publisher
Gizak A, McCubrey J, Rakus D. Cell-to-cell lactate shuttle operates in heart and is important in age-related heart failure. Aging (Albany NY). 2020;12:3388-3406 pubmed publisher
Kwon E, Yoo T, Joung H, Jo Y. Hydrocarboxylic acid receptor 1 in BAT regulates glucose uptake in mice fed a high-fat diet. PLoS ONE. 2020;15:e0228320 pubmed publisher
Duda P, Janczara J, McCubrey J, Gizak A, Rakus D. The Reverse Warburg Effect is Associated with Fbp2-Dependent Hif1α Regulation in Cancer Cells Stimulated by Fibroblasts. Cells. 2020;9: pubmed publisher
Dang D, Buhler J, Davis H, Thornton K, Scheffler T, Matarneh S. Inhibition of mitochondrial calcium uniporter enhances postmortem proteolysis and tenderness in beef cattle. Meat Sci. 2020;162:108039 pubmed publisher
Kilisch M, Mayer S, Mitkovski M, Roehse H, Hentrich J, Schwappach B, et al. A GTPase-induced switch in phospholipid affinity of collybistin contributes to synaptic gephyrin clustering. J Cell Sci. 2020;133: pubmed publisher
Apaoblaza A, Gerrard S, Matarneh S, Wicks J, Kirkpatrick L, England E, et al. Muscle from grass- and grain-fed cattle differs energetically. Meat Sci. 2020;161:107996 pubmed publisher
Choi Y, Song J, Lee J, Kim E, Kim C, Kim D, et al. Hyperpolarized [1-13C]lactate flux increased in the hippocampal region in diabetic mice. Mol Brain. 2019;12:88 pubmed publisher
Wible D, Chao H, Tang D, Bratton S. ATG5 cancer mutations and alternative mRNA splicing reveal a conjugation switch that regulates ATG12-ATG5-ATG16L1 complex assembly and autophagy. Cell Discov. 2019;5:42 pubmed publisher
Zhang J, Wang Y, Dong J, Yang J, Zhang Y, Wang F, et al. Development of a Simple Pretreatment Immunoassay Based on an Organic Solvent-Tolerant Nanobody for the Detection of Carbofuran in Vegetable and Fruit Samples. Biomolecules. 2019;9: pubmed publisher
Xu Q, Li X, Ma L, Loor J, Coleman D, Jia H, et al. Adipose tissue proteomic analysis in ketotic or healthy Holstein cows in early lactation1. J Anim Sci. 2019;97:2837-2849 pubmed publisher
Kaushik D, Bhattacharya A, Mirzaei R, Rawji K, Ahn Y, Rho J, et al. Enhanced glycolytic metabolism supports transmigration of brain-infiltrating macrophages in multiple sclerosis. J Clin Invest. 2019;129:3277-3292 pubmed publisher
Boyle J, Patronas N, Smirniotopoulos J, Herscovitch P, Dieckman W, Millo C, et al. CRH stimulation improves 18F-FDG-PET detection of pituitary adenomas in Cushing's disease. Endocrine. 2019;: pubmed publisher
Weiss Sadan T, Itzhak G, Kaschani F, Yu Z, Mahameed M, Anaki A, et al. Cathepsin L Regulates Metabolic Networks Controlling Rapid Cell Growth and Proliferation. Mol Cell Proteomics. 2019;: pubmed publisher
Xu Q, Li X, Ma L, Loor J, Coleman D, Jia H, et al. Adipose tissue proteomic analysis in ketotic or healthy Holstein cows in early lactation. J Anim Sci. 2019;: pubmed publisher
Sri Theivakadadcham V, Bergey B, Rosonina E. Sumoylation of DNA-bound transcription factor Sko1 prevents its association with nontarget promoters. PLoS Genet. 2019;15:e1007991 pubmed publisher
Vogg M, Beccari L, Iglesias Ollé L, Rampon C, Vriz S, Perruchoud C, et al. An evolutionarily-conserved Wnt3/β-catenin/Sp5 feedback loop restricts head organizer activity in Hydra. Nat Commun. 2019;10:312 pubmed publisher
Dodo M, Kitamura H, Shima H, Saigusa D, Wati S, Ota N, et al. Lactate dehydrogenase C is required for the protein expression of a sperm-specific isoform of lactate dehydrogenase A. J Biochem. 2019;165:323-334 pubmed publisher
HERRING B, Hoggatt A, Gupta A, Wo J. Gastroparesis is associated with decreased FOXF1 and FOXF2 in humans, and loss of FOXF1 and FOXF2 results in gastroparesis in mice. Neurogastroenterol Motil. 2019;31:e13528 pubmed publisher
Sikorski K, Mehta A, Inngjerdingen M, Thakor F, Kling S, Kalina T, et al. A high-throughput pipeline for validation of antibodies. Nat Methods. 2018;15:909-912 pubmed publisher
Lee D, Lee S, Shin D, Hong J. Chloride Influx of Anion Exchanger 2 Was Modulated by Calcium-Dependent Spinophilin in Submandibular Glands. Front Physiol. 2018;9:889 pubmed publisher
Xu M, Moresco J, Chang M, Mukim A, Smith D, Diedrich J, et al. SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy. PLoS Pathog. 2018;14:e1007071 pubmed publisher
Murray A, Varela F, Hyland T, Schoenbeck A, White J, Tanabe L, et al. Phosphorylation of the type II transmembrane serine protease, TMPRSS13, in hepatocyte growth factor activator inhibitor-1 and -2-mediated cell-surface localization. J Biol Chem. 2017;292:14867-14884 pubmed publisher
Rissanen I, Ahmed A, Azarm K, Beaty S, Hong P, Nambulli S, et al. Idiosyncratic Mòjiāng virus attachment glycoprotein directs a host-cell entry pathway distinct from genetically related henipaviruses. Nat Commun. 2017;8:16060 pubmed publisher
Hulley P, Bishop T, Vernet A, Schneider J, Edwards J, Athanasou N, et al. Hypoxia-inducible factor 1-alpha does not regulate osteoclastogenesis but enhances bone resorption activity via prolyl-4-hydroxylase 2. J Pathol. 2017;242:322-333 pubmed publisher
Stufft K, Elgin J, Patterson B, Matarneh S, Preisser R, Shi H, et al. Muscle characteristics only partially explain color variations in fresh hams. Meat Sci. 2017;128:88-96 pubmed publisher
Bednarski C, Tomczak K, Vom Hövel B, Weber W, Cathomen T. Targeted Integration of a Super-Exon into the CFTR Locus Leads to Functional Correction of a Cystic Fibrosis Cell Line Model. PLoS ONE. 2016;11:e0161072 pubmed publisher
Coleman S, Choi K, Root M, McGregor A. A Homolog Pentameric Complex Dictates Viral Epithelial Tropism, Pathogenicity and Congenital Infection Rate in Guinea Pig Cytomegalovirus. PLoS Pathog. 2016;12:e1005755 pubmed publisher
Park A, Yun T, Vigant F, Pernet O, Won S, Dawes B, et al. Nipah Virus C Protein Recruits Tsg101 to Promote the Efficient Release of Virus in an ESCRT-Dependent Pathway. PLoS Pathog. 2016;12:e1005659 pubmed publisher
Takenouchi T, Tsukimoto M, Iwamaru Y, Sugama S, Sekiyama K, Sato M, et al. Extracellular ATP induces unconventional release of glyceraldehyde-3-phosphate dehydrogenase from microglial cells. Immunol Lett. 2015;167:116-24 pubmed publisher
Kim J, Han J, Jang Y, Kim S, Lee M, Ryu M, et al. High-capacity glycolytic and mitochondrial oxidative metabolisms mediate the growth ability of glioblastoma. Int J Oncol. 2015;47:1009-16 pubmed publisher
Pastor Soler N, Sutton T, Mang H, Kinlough C, Gendler S, Madsen C, et al. Muc1 is protective during kidney ischemia-reperfusion injury. Am J Physiol Renal Physiol. 2015;308:F1452-62 pubmed publisher
Pentecost M, Vashisht A, Lester T, Voros T, Beaty S, Park A, et al. Evidence for ubiquitin-regulated nuclear and subnuclear trafficking among Paramyxovirinae matrix proteins. PLoS Pathog. 2015;11:e1004739 pubmed publisher
Sun S, Ling S, Qiu J, Albuquerque C, Zhou Y, Tokunaga S, et al. ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP. Nat Commun. 2015;6:6171 pubmed publisher
product information
master code :
NBP1-48336
SKU :
NBP1-48336
product name :
Lactate Dehydrogenase A/LDHA Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The Lactate Dehydrogenase A/LDHA Antibody - BSA Free from Novus is a rabbit polyclonal antibody to Lactate Dehydrogenase A/LDHA. This antibody reacts with bovine,human,mouse,porcine,rat. The Lactate Dehydrogenase A/LDHA Antibody - BSA Free has been validated for the following applications: Immunohistochemistry-Frozen,Western Blot,Immunocytochemistry/ Immunofluorescence,IF/IHC,ELISA,Simple Western,Immunohistochemistry-Paraffin,Flow Cytometry,Immunohistochemistry.
target :
Lactate Dehydrogenase A/LDHA
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Synthetic peptide made to a C-terminal portion of the human Lactate Dehydrogenase A protein (within residues 280-332). [Swiss-Prot# P00338]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Bovine,Human,Mouse,Porcine,Rat
theoretical molecular weight :
36 kDa
gene symbol :
LDHA
accessionNumbers :
P00338
applications :
Western Blot,Immunocytochemistry/ Immunofluorescence,IF/IHC,ELISA,Simple Western,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Flow Cytometry,Immunohistochemistry
USD :
419 USD
alt names :
Cell proliferation-inducing gene 19 protein, EC 1.1.1, EC 1.1.1.27, GSD11, lactate dehydrogenase A, lactate dehydrogenase M, LDH muscle subunit, LDH1, LDH-A, LDHM, LDH-M, L-lactate dehydrogenase A chain, proliferation-inducing gene 19, Renal carcinoma antigen NY-REN-59
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.