product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
p62/SQSTM1 Antibody - BSA Free
catalog :
NBP1-48320
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
DyLight 350
clone name :
OTI2B3
reactivity :
human, mouse, rat, chicken
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 115
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 1g
Yoon Y, Go G, Yoon S, Lim J, Lee G, Lee J, et al. Melatonin Treatment Improves Renal Fibrosis via miR-4516/SIAH3/PINK1 Axis. Cells. 2021;10: pubmed publisher
  • western blot; mouse; loading ...; fig 1c
Cabrera J, Manivanh R, North B, Leib D. The ESCRT-Related ATPase Vps4 Is Modulated by Interferon during Herpes Simplex Virus 1 Infection. MBio. 2019;10: pubmed publisher
  • western blot; human; loading ...; fig 2d
Eritja N, Chen B, Rodríguez Barrueco R, Santacana M, Gatius S, Vidal A, et al. Autophagy orchestrates adaptive responses to targeted therapy in endometrial cancer. Autophagy. 2017;13:608-624 pubmed publisher
  • immunocytochemistry; mouse; fig 3
Katzenell S, Leib D. Herpes Simplex Virus and Interferon Signaling Induce Novel Autophagic Clusters in Sensory Neurons. J Virol. 2016;90:4706-4719 pubmed publisher
Tedeschi V, Nele V, Valsecchi V, Anzilotti S, Vinciguerra A, Zucaro L, et al. Nanoparticles encapsulating phosphatidylinositol derivatives promote neuroprotection and functional improvement in preclinical models of ALS via a long-lasting activation of TRPML1 lysosomal channel. Pharmacol Res. 2024;210:107491 pubmed publisher
Tao X, Liu J, Diaz Perez Z, Foley J, Nwafor A, Stewart T, et al. Reduction of spermine synthase enhances autophagy to suppress Tau accumulation. Cell Death Dis. 2024;15:333 pubmed publisher
You W, Knoops K, Berendschot T, Benedikter B, Webers C, Reutelingsperger C, et al. PGC-1a mediated mitochondrial biogenesis promotes recovery and survival of neuronal cells from cellular degeneration. Cell Death Discov. 2024;10:180 pubmed publisher
Macke A, Divita T, Pachikov A, Mahalingam S, Bellamkonda R, Rasineni K, et al. Alcohol-induced Golgiphagy is triggered by the downregulation of Golgi GTPase RAB3D. Autophagy. 2024;20:1537-1558 pubmed publisher
Yang K, Nam S, Lee G, Yang G, Lee M, Bang G, et al. Induction of Autophagy by Extract from Corydalis heterocarpa for Skin Anti-Aging. Mar Drugs. 2024;22: pubmed publisher
Fan R, Sportelli C, Lai Y, Salehe S, Pinnell J, Brown H, et al. A partial Drp1 knockout improves autophagy flux independent of mitochondrial function. Mol Neurodegener. 2024;19:26 pubmed publisher
Bayona C, Alza L, Ran x111 elovi x107 T, Sall xe1 n M, Visa A, Cant xed C, et al. Tetralol derivative NNC-55-0396 targets hypoxic cells in the glioblastoma microenvironment: an organ-on-chip approach. Cell Death Dis. 2024;15:127 pubmed publisher
Yu F, Li L, Gu Y, Wang S, Zhou L, Cheng X, et al. Lysine demethylase 5C inhibits transcription of prefoldin subunit 5 to activate c-Myc signal transduction and colorectal cancer progression. Mol Med. 2024;30:9 pubmed publisher
Elbialy A, Kitauchi M, Yamanouchi D. Antioxidants and azd0156 Rescue Inflammatory Response in Autophagy-Impaired Macrophages. Int J Mol Sci. 2023;25: pubmed publisher
Yuan J, Zhao F, Liu Y, Liu H, Zhang K, Tian X, et al. Effects of Lactiplantibacillus plantarum on oxidative stress, mitophagy, and NLRP3 inflammasome activation in broiler breast meat. Poult Sci. 2023;102:103128 pubmed publisher
Cui S, Zhang T, Xiong X, Zhao J, Cao Q, Zhou H, et al. Detergent-insoluble PFN1 inoculation expedites disease onset and progression in PFN1 transgenic rats. Front Neurosci. 2023;17:1279259 pubmed publisher
Santarelli R, Evangelista L, Pompili C, Lo Presti S, Rossi A, Arena A, et al. EBV infection of primary colonic epithelial cells causes inflammation, DDR and autophagy dysregulation, effects that may predispose to IBD and carcinogenesis. Virus Res. 2023;338:199236 pubmed publisher
Chen M, Menon M, Wang W, Fu J, Yi Z, Sun Z, et al. HCK induces macrophage activation to promote renal inflammation and fibrosis via suppression of autophagy. Nat Commun. 2023;14:4297 pubmed publisher
Chae C, Yoon J, Lim J, Park J, Cho J, Jung Y, et al. TRIM16-mediated lysophagy suppresses high-glucose-accumulated neuronal Aβ. Autophagy. 2023;19:2752-2768 pubmed publisher
O Rourke R, Erdemir G, Huang Y. Assays of Monitoring and Measuring Autophagic Flux for iPSC-Derived Human Neurons and Other Brain Cell Types. Methods Mol Biol. 2023;2683:221-233 pubmed publisher
Southwell N, Primiano G, Nadkarni V, Attarwala N, Beattie E, Miller D, et al. A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy. EMBO Mol Med. 2023;15:e16951 pubmed publisher
Paunovic V, Vucicevic L, Misirkic Marjanovic M, Perovic V, Ristic B, Bosnjak M, et al. Autophagy Receptor p62 Regulates SARS-CoV-2-Induced Inflammation in COVID-19. Cells. 2023;12: pubmed publisher
Sep xfa lveda C, Rodr xed guez J, Monsalves xc1 lvarez M, Donoso Barraza C, Pino de la Fuente F, Mat xed as I, et al. The CB1 cannabinoid receptor regulates autophagy in the tibialis anterior skeletal muscle in mice. Biol Res. 2023;56:14 pubmed publisher
Kim S, Cho Y, Kim Y, Park J, Yoo S, Gwak J, et al. Endolysosomal impairment by binding of amyloid beta or MAPT/Tau to V-ATPase and rescue via the HYAL-CD44 axis in Alzheimer disease. Autophagy. 2023;:1-20 pubmed publisher
Meyers A, Wang Z, Han W, Zhao Q, Zabalawi M, Duan L, et al. Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation. Cell Rep. 2023;42:111941 pubmed publisher
Lee C, Tsai J, Lee H, Chen Y, Chen Y, Hsieh Y, et al. Blockage of Autophagy Increases Timosaponin AIII-Induced Apoptosis of Glioma Cells In Vitro and In Vivo. Cells. 2022;12: pubmed publisher
Shearn C, Anderson A, Devereux M, Orlicky D, Michel C, Petersen D, et al. The autophagic protein p62 is a target of reactive aldehydes in human and murine cholestatic liver disease. PLoS ONE. 2022;17:e0276879 pubmed publisher
Sapienza S, Tedeschi V, Apicella B, Palestra F, Russo C, Piccialli I, et al. Size-Based Effects of Anthropogenic Ultrafine Particles on Lysosomal TRPML1 Channel and Autophagy in Motoneuron-like Cells. Int J Mol Sci. 2022;23: pubmed publisher
Wang Y, Liao J, Chen K, Su H, Liu P, Chen Y, et al. Lumbrokinase regulates endoplasmic reticulum stress to improve neurological deficits in ischemic stroke. Neuropharmacology. 2022;221:109277 pubmed publisher
Paunovic V, Peric S, Vukovic I, Stamenkovic M, Milosevic E, Stevanovic D, et al. Downregulation of LKB1/AMPK Signaling in Blood Mononuclear Cells Is Associated with the Severity of Guillain-Barre Syndrome. Cells. 2022;11: pubmed publisher
Wang L, Sun Y, Kong F, Jiang Y, An M, Jin B, et al. Mild Hypothermia Alleviates Complement C5a-Induced Neuronal Autophagy During Brain Ischemia-Reperfusion Injury After Cardiac Arrest. Cell Mol Neurobiol. 2022;: pubmed publisher
Wen Y, Chen Z, Tian Y, Yang M, Dong Q, Yang Y, et al. Incomplete autophagy promotes the proliferation of Mycoplasma hyopneumoniae through the JNK and Akt pathways in porcine alveolar macrophages. Vet Res. 2022;53:62 pubmed publisher
Liu H, Li X, Shi S, Zhou Y, Zhang K, Wang Y, et al. Chlorogenic acid improves growth performance and intestinal health through autophagy-mediated nuclear factor erythroid 2-related factor 2 pathway in oxidatively stressed broilers induced by dexamethasone. Poult Sci. 2022;101:102036 pubmed publisher
Peischard S, M xf6 ller M, Disse P, Ho H, Verkerk A, Strutz Seebohm N, et al. Virus-induced inhibition of cardiac pacemaker channel HCN4 triggers bradycardia in human-induced stem cell system. Cell Mol Life Sci. 2022;79:440 pubmed publisher
Tao X, Zhu Y, Diaz Perez Z, Yu S, Foley J, Stewart T, et al. Phenylbutyrate modulates polyamine acetylase and ameliorates Snyder-Robinson syndrome in a Drosophila model and patient cells. JCI Insight. 2022;7: pubmed publisher
Amirkavei M, Plastino F, Kvanta A, Kaarniranta K, Andr xe9 H, Koskelainen A. Hormetic Heat Shock Enhances Autophagy through HSF1 in Retinal Pigment Epithelium Cells. Cells. 2022;11: pubmed publisher
Chen S, Acosta D, Li L, Liang J, Chang Y, Wang C, et al. Wolframin is a novel regulator of tau pathology and neurodegeneration. Acta Neuropathol. 2022;143:547-569 pubmed publisher
Santarelli R, Pompili C, Gilardini Montani M, Evangelista L, Gonnella R, Cirone M. 3,4-Dihydroxyphenylethanol (DPE or Hydroxytyrosol) Counteracts ERK1/2 and mTOR Activation, Pro-Inflammatory Cytokine Release, Autophagy and Mitophagy Reduction Mediated by Benzo[a]pyrene in Primary Human Colonic Epithelial Cells. Pharmaceutics. 2022;14: pubmed publisher
Xu Z, Fu T, Guo Q, Zhou D, Sun W, Zhou Z, et al. Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength. Nat Commun. 2022;13:894 pubmed publisher
Thakur A, Luthra Guptasarma M. Differences in Cellular Clearing Mechanisms of Aggregates of Two Subtypes of HLA-B27. Front Immunol. 2021;12:795053 pubmed publisher
Wang T, Yao J, Jia L, Fort P, Zacks D. Loss of αA or αB-Crystallin Accelerates Photoreceptor Cell Death in a Mouse Model of P23H Autosomal Dominant Retinitis Pigmentosa. Int J Mol Sci. 2021;23: pubmed publisher
Luk H, Appell C, Levitt D, Jiwan N, Vingren J. Differential Autophagy Response in Men and Women After Muscle Damage. Front Physiol. 2021;12:752347 pubmed publisher
Huang P, Chiu C, Hsiao M, Yow J, Tzang B, Hsu T. Potential of antiviral drug oseltamivir for the treatment of liver cancer. Int J Oncol. 2021;59: pubmed publisher
Streubel Gallasch L, Zysk M, Beretta C, Erlandsson A. Traumatic brain injury in the presence of Aβ pathology affects neuronal survival, glial activation and autophagy. Sci Rep. 2021;11:22982 pubmed publisher
Wang C, Lin S, Huang Y, Hsieh C, Chang H, Chen H, et al. Paired-like homeodomain 2B contributes to tumour progression and anti-autophagy in human lung cancer. Am J Cancer Res. 2021;11:4900-4918 pubmed
Kim N, Hwang S, Yang Y, Kim Y. Temozolomide abrogates the aggressiveness of urothelial carcinoma cells by enhancing senescence and depleting the side population. Oncol Lett. 2021;22:845 pubmed publisher
Krunic M, Ristic B, Bosnjak M, Paunovic V, Tovilović Kovačević G, Zogovic N, et al. Graphene quantum dot antioxidant and proautophagic actions protect SH-SY5Y neuroblastoma cells from oxidative stress-mediated apoptotic death. Free Radic Biol Med. 2021;177:167-180 pubmed publisher
Zhao J, Ran M, Yang T, Chen L, Ji P, Xu X, et al. Bicyclol Alleviates Signs of BDL-Induced Cholestasis by Regulating Bile Acids and Autophagy-Mediated HMGB1/p62/Nrf2 Pathway. Front Pharmacol. 2021;12:686502 pubmed publisher
Wang Z, Wen Y, Zhou B, Tian Y, Ning Y, Ding H. Incomplete autophagy promotes the replication of Mycoplasma hyopneumoniae. J Microbiol. 2021;59:782-791 pubmed publisher
McGillis L, Bronte Tinkew D, Dang F, Capurro M, Prashar A, Ricciuto A, et al. Vitamin D deficiency enhances expression of autophagy-regulating miR-142-3p in mouse and "involved" IBD patient intestinal tissues. Am J Physiol Gastrointest Liver Physiol. 2021;321:G171-G184 pubmed publisher
Du L, Wu Y, Han X, Wang C, Li A, Huang G. NICE-3-knockdown induces cell cycle arrest and autophagy in lung adenocarcinoma cells via the AKT/mTORC1 signaling pathway. Exp Ther Med. 2021;21:625 pubmed publisher
La Cunza N, Tan L, Thamban T, Germer C, Rathnasamy G, Toops K, et al. Mitochondria-dependent phase separation of disease-relevant proteins drives pathological features of age-related macular degeneration. JCI Insight. 2021;6: pubmed publisher
Guo W, Wang Q, Pan S, Li J, Wang Y, Shu Y, et al. The ERK1/2-ATG13-FIP200 signaling cascade is required for autophagy induction to protect renal cells from hypoglycemia-induced cell death. J Cell Physiol. 2021;: pubmed publisher
Tu C, Li H, Liu X, Wang Y, Li W, Meng L, et al. TDRD7 participates in lens development and spermiogenesis by mediating autophagosome maturation. Autophagy. 2021;:1-17 pubmed publisher
Yang F, Liao J, Yu W, Qiao N, Guo J, Han Q, et al. Exposure to copper induces mitochondria-mediated apoptosis by inhibiting mitophagy and the PINK1/parkin pathway in chicken (Gallus gallus) livers. J Hazard Mater. 2021;408:124888 pubmed publisher
Akaraphutiporn E, Sunaga T, Bwalya E, Yanlin W, Carol M, Okumura M. An Insight into the Role of Apoptosis and Autophagy in Nitric Oxide-Induced Articular Chondrocyte Cell Death. Cartilage. 2020;:1947603520976768 pubmed publisher
Mukherjee T, Ramaglia V, Abdel Nour M, Bianchi A, Tsalikis J, Chau H, et al. The eIF2α kinase HRI triggers the autophagic clearance of cytosolic protein aggregates. J Biol Chem. 2021;296:100050 pubmed publisher
Wang W, Li A, Han X, Wang Q, Guo J, Wu Y, et al. DEPDC1 up-regulates RAS expression to inhibit autophagy in lung adenocarcinoma cells. J Cell Mol Med. 2020;: pubmed publisher
Mukhopadhyay S, Praharaj P, Naik P, Talukdar S, Emdad L, Das S, et al. Identification of Annexin A2 as a key mTOR target to induce roller coaster pattern of autophagy fluctuation in stress. Biochim Biophys Acta Mol Basis Dis. 2020;1866:165952 pubmed publisher
Koepke L, Winter B, Grenzner A, Regensburger K, Engelhart S, van der Merwe J, et al. An improved method for high-throughput quantification of autophagy in mammalian cells. Sci Rep. 2020;10:12241 pubmed publisher
Haney M, Zhao Y, Fay J, Duhyeong H, Wang M, Wang H, et al. Genetically modified macrophages accomplish targeted gene delivery to the inflamed brain in transgenic Parkin Q311X(A) mice: importance of administration routes. Sci Rep. 2020;10:11818 pubmed publisher
Yefimova M, Lefevre C, Bashamboo A, Eozenou C, Burel A, Lavault M, et al. Granulosa cells provide elimination of apoptotic oocytes through unconventional autophagy-assisted phagocytosis. Hum Reprod. 2020;35:1346-1362 pubmed publisher
Sacitharan P, Bou Gharios G, Edwards J. SIRT1 directly activates autophagy in human chondrocytes. Cell Death Discov. 2020;6:41 pubmed publisher
Karuppan M, Ojha C, Rodriguez M, Lapierre J, Aman M, Kashanchi F, et al. Reduced-Beclin1-Expressing Mice Infected with Zika-R103451 and Viral-Associated Pathology during Pregnancy. Viruses. 2020;12: pubmed publisher
Chae C, Lee H, Choi G, Jung Y, Kim J, Lim J, et al. High glucose-mediated PICALM and mTORC1 modulate processing of amyloid precursor protein via endosomal abnormalities. Br J Pharmacol. 2020;177:3828-3847 pubmed publisher
Manivanh R, Mehrbach J, Charron A, Grassetti A, Cerón S, Taylor S, et al. Herpes Simplex Virus 1 ICP34.5 Alters Mitochondrial Dynamics in Neurons. J Virol. 2020;94: pubmed publisher
Alza L, Nager M, Visa A, Canti C, Herreros J. FAK Inhibition Induces Glioblastoma Cell Senescence-Like State through p62 and p27. Cancers (Basel). 2020;12: pubmed publisher
Jang J, Eom J, Jeung H, Chung H, Kim Y, Kim J, et al. PERK/NRF2 and autophagy form a resistance mechanism against G9a inhibition in leukemia stem cells. J Exp Clin Cancer Res. 2020;39:66 pubmed publisher
Khobrekar N, Quintremil S, Dantas T, Vallee R. The Dynein Adaptor RILP Controls Neuronal Autophagosome Biogenesis, Transport, and Clearance. Dev Cell. 2020;53:141-153.e4 pubmed publisher
Wang R, Wang W, Li A, Wang Y, Jin J, Huang Z, et al. Lipopolysaccharide enhances DNA-induced IFN-β expression and autophagy by upregulating cGAS expression in A549 cells. Exp Ther Med. 2019;18:4157-4164 pubmed publisher
la Fuente F, Quezada L, Sepúlveda C, Monsálves Álvarez M, Rodriguez J, Sacristán C, et al. Exercise regulates lipid droplet dynamics in normal and fatty liver. Biochim Biophys Acta Mol Cell Biol Lipids. 2019;1864:158519 pubmed publisher
Tedeschi V, Petrozziello T, Sisalli M, Boscia F, Canzoniero L, Secondo A. The activation of Mucolipin TRP channel 1 (TRPML1) protects motor neurons from L-BMAA neurotoxicity by promoting autophagic clearance. Sci Rep. 2019;9:10743 pubmed publisher
Qiu Y, Yao J, Jia L, Thompson D, Zacks D. Shifting the balance of autophagy and proteasome activation reduces proteotoxic cell death: a novel therapeutic approach for restoring photoreceptor homeostasis. Cell Death Dis. 2019;10:547 pubmed publisher
Selka A, Doiron J, Lyons P, Dastous S, Chiasson A, Cormier M, et al. Discovery of a novel 2,5-dihydroxycinnamic acid-based 5-lipoxygenase inhibitor that induces apoptosis and may impair autophagic flux in RCC4 renal cancer cells. Eur J Med Chem. 2019;179:347-357 pubmed publisher
Song J, Zhao X, Feng Y, Xu S, Zhang Y, Wei L. Involvement of proapoptotic genes in autophagic cell death induced by irradiation. Cell Death Discov. 2017;3:17068 pubmed publisher
Chai Q, Wang X, Qiang L, Zhang Y, Ge P, Lu Z, et al. A Mycobacterium tuberculosis surface protein recruits ubiquitin to trigger host xenophagy. Nat Commun. 2019;10:1973 pubmed publisher
Yefimova M, Buschiazzo A, Burel A, Lavault M, Pimentel C, Jouve G, et al. Autophagy is increased in cryptorchid testis resulting in abnormal spermatozoa. Asian J Androl. 2019;21:570-576 pubmed publisher
Nyman M, Jokilammi A, Boström P, Kurki S, Sainio A, Grénman S, et al. Decorin Expression in Human Vulva Carcinoma: Oncosuppressive Effect of Decorin cDNA Transduction on Carcinoma Cells. J Histochem Cytochem. 2019;67:511-522 pubmed publisher
Yao L, Zhu Z, Wu J, Zhang Y, Zhang H, Sun X, et al. MicroRNA-124 regulates the expression of p62/p38 and promotes autophagy in the inflammatory pathogenesis of Parkinson's disease. FASEB J. 2019;33:8648-8665 pubmed publisher
Ye B, Wang Q, Hu H, Shen Y, Fan C, Chen P, et al. Restoring autophagic flux attenuates cochlear spiral ganglion neuron degeneration by promoting TFEB nuclear translocation via inhibiting MTOR. Autophagy. 2019;15:998-1016 pubmed publisher
Choi G, Oh J, Lee H, Chae C, Kim J, Jung Y, et al. Glucocorticoid-mediated ER-mitochondria contacts reduce AMPA receptor and mitochondria trafficking into cell terminus via microtubule destabilization. Cell Death Dis. 2018;9:1137 pubmed publisher
Oh J, Choi G, Lee H, Jung Y, Chae C, Kim J, et al. 17β-Estradiol protects mesenchymal stem cells against high glucose-induced mitochondrial oxidants production via Nrf2/Sirt3/MnSOD signaling. Free Radic Biol Med. 2019;130:328-342 pubmed publisher
Yao J, Qiu Y, Jia L, Zacks D. Autophagosome immunoisolation from GFP-LC3B mouse tissue. Autophagy. 2019;15:341-346 pubmed publisher
Lee J, Rao M, Yang D, Stavrides P, Im E, Pensalfini A, et al. Transgenic expression of a ratiometric autophagy probe specifically in neurons enables the interrogation of brain autophagy in vivo. Autophagy. 2019;15:543-557 pubmed publisher
Ciric D, Martinovic T, Petricevic S, Trajkovic V, Bumbasirevic V, Kravic Stevovic T. Metformin exacerbates and simvastatin attenuates myelin damage in high fat diet-fed C57BL/6 J mice. Neuropathology. 2018;38:468-474 pubmed publisher
Yao J, Qiu Y, Frontera E, Jia L, Khan N, Klionsky D, et al. Inhibiting autophagy reduces retinal degeneration caused by protein misfolding. Autophagy. 2018;14:1226-1238 pubmed publisher
Chen P, Liu A, Ho K, Chiu Y, Anne Lin Z, Lee Y, et al. microRNA-199a/b-5p enhance imatinib efficacy via repressing WNT2 signaling-mediated protective autophagy in imatinib-resistant chronic myeloid leukemia cells. Chem Biol Interact. 2018;291:144-151 pubmed publisher
Lapierre J, Rodriguez M, Ojha C, El Hage N. Critical Role of Beclin1 in HIV Tat and Morphine-Induced Inflammation and Calcium Release in Glial Cells from Autophagy Deficient Mouse. J Neuroimmune Pharmacol. 2018;13:355-370 pubmed publisher
Sorbara M, Foerster E, Tsalikis J, Abdel Nour M, Mangiapane J, Sirluck Schroeder I, et al. Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria. Cell Host Microbe. 2018;23:644-652.e5 pubmed publisher
Paunovic V, Petrovic I, Milenkovic M, Janjetovic K, Pravica V, Dujmovic I, et al. Autophagy-independent increase of ATG5 expression in T cells of multiple sclerosis patients. J Neuroimmunol. 2018;319:100-105 pubmed publisher
Nager M, Sallán M, Visa A, Pushparaj C, Santacana M, Macià A, et al. Inhibition of WNT-CTNNB1 signaling upregulates SQSTM1 and sensitizes glioblastoma cells to autophagy blockers. Autophagy. 2018;14:619-636 pubmed publisher
Sanborn R, Ross H, Aung S, Acheson A, Moudgil T, Puri S, et al. A pilot study of an autologous tumor-derived autophagosome vaccine with docetaxel in patients with stage IV non-small cell lung cancer. J Immunother Cancer. 2017;5:103 pubmed publisher
Bilanges B, Alliouachene S, Pearce W, Morelli D, Szabadkai G, Chung Y, et al. Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism. Nat Commun. 2017;8:1804 pubmed publisher
Mishra S, Gao Y, Deng Y, Chalfant C, Hinchcliffe E, Brown R. CPTP: A sphingolipid transfer protein that regulates autophagy and inflammasome activation. Autophagy. 2018;14:862-879 pubmed publisher
Rostami J, Holmqvist S, Lindström V, Sigvardson J, Westermark G, Ingelsson M, et al. Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes. J Neurosci. 2017;37:11835-11853 pubmed publisher
Jiang P, Gan M, Yen S, McLean P, Dickson D. Impaired endo-lysosomal membrane integrity accelerates the seeding progression of α-synuclein aggregates. Sci Rep. 2017;7:7690 pubmed publisher
Lee K, Lee S, Lee H, Choi G, Jung Y, Kim D, et al. Amyloid β1-42 (Aβ1-42) Induces the CDK2-Mediated Phosphorylation of Tau through the Activation of the mTORC1 Signaling Pathway While Promoting Neuronal Cell Death. Front Mol Neurosci. 2017;10:229 pubmed publisher
Shen L, Yang Y, Ou T, Key C, Tong S, Sequeira R, et al. Dietary PUFAs attenuate NLRP3 inflammasome activation via enhancing macrophage autophagy. J Lipid Res. 2017;58:1808-1821 pubmed publisher
Germic N, Stojkov D, Oberson K, Yousefi S, Simon H. Neither eosinophils nor neutrophils require ATG5-dependent autophagy for extracellular DNA trap formation. Immunology. 2017;152:517-525 pubmed publisher
Kim Y, Jeong E, Nah J, Yoo S, Lee W, Kim Y, et al. Pimozide reduces toxic forms of tau in TauC3 mice via 5' adenosine monophosphate-activated protein kinase-mediated autophagy. J Neurochem. 2017;142:734-746 pubmed publisher
Chen C, Lu Y, Siu H, Guan J, Zhu L, Zhang S, et al. Identification of Novel Vacuolin-1 Analogues as Autophagy Inhibitors by Virtual Drug Screening and Chemical Synthesis. Molecules. 2017;22: pubmed publisher
Su H, Chu Y, Liao J, Wang Y, Jan M, Lin C, et al. Phellinus linteus Mycelium Alleviates Myocardial Ischemia-Reperfusion Injury through Autophagic Regulation. Front Pharmacol. 2017;8:175 pubmed publisher
Wang S, Seaberg B, Paez Colasante X, Rimer M. Defective Acetylcholine Receptor Subunit Switch Precedes Atrophy of Slow-Twitch Skeletal Muscle Fibers Lacking ERK1/2 Kinases in Soleus Muscle. Sci Rep. 2016;6:38745 pubmed publisher
Kim D, Lee K, Gabr A, Choi G, Kim J, Ko S, et al. A?-Induced Drp1 phosphorylation through Akt activation promotes excessive mitochondrial fission leading to neuronal apoptosis. Biochim Biophys Acta. 2016;1863:2820-2834 pubmed publisher
Tan K, Ho M, Cho H, Yu J, Hung J, Yu A. Fucosylation of LAMP-1 and LAMP-2 by FUT1 correlates with lysosomal positioning and autophagic flux of breast cancer cells. Cell Death Dis. 2016;7:e2347 pubmed publisher
Sidjanin D, Park A, Ronchetti A, Martins J, Jackson W. TBC1D20 mediates autophagy as a key regulator of autophagosome maturation. Autophagy. 2016;12:1759-1775 pubmed
Song E, Lee S, Lim H, Kim J, Jang K, Choi S, et al. Vibrio vulnificus VvhA induces autophagy-related cell death through the lipid raft-dependent c-Src/NOX signaling pathway. Sci Rep. 2016;6:27080 pubmed publisher
Schwab A, Ebert A. Neurite Aggregation and Calcium Dysfunction in iPSC-Derived Sensory Neurons with Parkinson's Disease-Related LRRK2 G2019S Mutation. Stem Cell Reports. 2015;5:1039-1052 pubmed publisher
Fan T, Bu L, Wang W, Ma S, Liu J, Deng W, et al. Tumor growth suppression by inhibiting both autophagy and STAT3 signaling in HNSCC. Oncotarget. 2015;6:43581-93 pubmed publisher
Dever S, Rodriguez M, Lapierre J, COSTIN B, El Hage N. Differing roles of autophagy in HIV-associated neurocognitive impairment and encephalitis with implications for morphine co-exposure. Front Microbiol. 2015;6:653 pubmed publisher
Lin C, Jan M, Kuo J. Exploring MicroRNA Expression Profiles Related to the mTOR Signaling Pathway in Mouse Embryonic Fibroblast Cells Treated with Polyethylenimine. Mol Pharm. 2015;12:2858-68 pubmed publisher
Yao J, Jia L, Khan N, Lin C, Mitter S, Boulton M, et al. Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium. Autophagy. 2015;11:939-53 pubmed publisher
Lin H. In Vitro and in Vivo Atheroprotective Effects of Gossypetin against Endothelial Cell Injury by Induction of Autophagy. Chem Res Toxicol. 2015;28:202-15 pubmed
Sun K, Chen M, Tu M, Wang I, Chang S, Li C. MicroRNA-20a regulates autophagy related protein-ATG16L1 in hypoxia-induced osteoclast differentiation. Bone. 2015;73:145-53 pubmed publisher
Rožman S, Yousefi S, Oberson K, Kaufmann T, Benarafa C, Simon H. The generation of neutrophils in the bone marrow is controlled by autophagy. Cell Death Differ. 2015;22:445-56 pubmed publisher
Wang W, Lin S, Chang W, Liu L, Li T, Kuo C, et al. Hinokitiol induces autophagy in murine breast and colorectal cancer cells. Environ Toxicol. 2016;31:77-84 pubmed publisher
product information
master code :
NBP1-48320
SKU :
NBP1-48320
product name :
p62/SQSTM1 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The p62/SQSTM1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to p62/SQSTM1. This antibody reacts with avian - chicken,chicken,human,mouse,porcine,rat. The p62/SQSTM1 Antibody - BSA Free has been validated for the following applications: Western Blot,Block/Neutralize,Immunocytochemistry/ Immunofluorescence,Simple Western,IF/IHC,Flow Cytometry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry Free-Floating,Immunocytochemistry,Immunohistochemistry.
target :
p62/SQSTM1
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Partial recombinant protein made to the C terminal of the human p62/SQSTM1 protein (within residues 300-440). [Swiss-Prot Q13501]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Avian - Chicken,Chicken,Human,Mouse,Porcine,Rat
gene symbol :
SQSTM1
Antibody validation :
Biological Validation
accessionNumbers :
Q13501, Q64337, O08623
applications :
Western Blot,Block/Neutralize,Immunocytochemistry/ Immunofluorescence,Simple Western,IF/IHC,Flow Cytometry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry Free-Floating,Immunocytochemistry,Immunohistochemistry
USD :
409 USD
alt names :
A170, Autophagy Receptor P62, DMRV, EBI3-associated protein of 60 kDa, EBI3-associated protein p60, EBIAP, FTDALS3, NADGP, ORCA, OSIL, oxidative stress induced like, p60PDB3, p62, p62B, Paget disease of bone 3, PDB3, phosphotyrosine independent ligand for the Lck SH2 domain p62, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, sequestosome 1, sequestosome-1, Ubiquitin-binding protein p62, ZIP3
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.