N-Cadherin Antibody (13A9) - BSA Free | Novus Biologicals NBP1-48309 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

N-Cadherin Antibody (13A9) - BSA Free

catalog :

NBP1-48309

quantity :

0.1 ml (also 0.025 ml)

price :

449 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

13A9

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 42

Published Application/Species/Sample/Dilution	Reference
western blot; rat; loading ...; fig s1	Hlavac N, VandeVord P. Astrocyte Mechano-Activation by High-Rate Overpressure Involves Alterations in Structural and Junctional Proteins. Front Neurol. 2019;10:99 pubmed publisher
western blot; human	Chow A, Ng L, Lam C, Wong S, Wan T, Cheng N, et al. The Enhanced metastatic potential of hepatocellular carcinoma (HCC) cells with sorafenib resistance. PLoS ONE. 2013;8:e78675 pubmed publisher
western blot; human	Maeda M, Johnson E, Mandal S, Lawson K, Keim S, Svoboda R, et al. Expression of inappropriate cadherins by epithelial tumor cells promotes endocytosis and degradation of E-cadherin via competition for p120(ctn). Oncogene. 2006;25:4595-604 pubmed
immunohistochemistry - paraffin section; human	Jaggi M, Nazemi T, Abrahams N, Baker J, Galich A, Smith L, et al. N-cadherin switching occurs in high Gleason grade prostate cancer. Prostate. 2006;66:193-9 pubmed
immunoprecipitation; human immunocytochemistry; human western blot; human	Wahl J, Kim Y, Cullen J, Johnson K, Wheelock M. N-cadherin-catenin complexes form prior to cleavage of the proregion and transport to the plasma membrane. J Biol Chem. 2003;278:17269-76 pubmed
flow cytometry; human immunoprecipitation; human immunocytochemistry; human western blot; human	Van Aken E, Papeleu P, De Potter P, Bruyneel E, Philippe J, Seregard S, et al. Structure and function of the N-cadherin/catenin complex in retinoblastoma. Invest Ophthalmol Vis Sci. 2002;43:595-602 pubmed
immunocytochemistry; human western blot; human	Reyes Mugica M, Meyerhardt J, Rzasa J, Rimm D, Johnson K, Wheelock M, et al. Truncated DCC reduces N-cadherin/catenin expression and calcium-dependent cell adhesion in neuroblastoma cells. Lab Invest. 2001;81:201-10 pubmed
immunocytochemistry; human western blot; human	Kim J, Islam S, Kim Y, Prudoff R, Sass K, Wheelock M, et al. N-Cadherin extracellular repeat 4 mediates epithelial to mesenchymal transition and increased motility. J Cell Biol. 2000;151:1193-206 pubmed
immunocytochemistry; human western blot; human	Nieman M, Prudoff R, Johnson K, Wheelock M. N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression. J Cell Biol. 1999;147:631-44 pubmed
immunocytochemistry; human western blot; human	Makrigiannakis A, Coukos G, Christofidou Solomidou M, Gour B, Radice G, Blaschuk O, et al. N-cadherin-mediated human granulosa cell adhesion prevents apoptosis: a role in follicular atresia and luteolysis?. Am J Pathol. 1999;154:1391-406 pubmed
immunocytochemistry; rat western blot; rat	Benson D, Tanaka H. N-cadherin redistribution during synaptogenesis in hippocampal neurons. J Neurosci. 1998;18:6892-904 pubmed
immunocytochemistry; human	Navarro P, Ruco L, Dejana E. Differential localization of VE- and N-cadherins in human endothelial cells: VE-cadherin competes with N-cadherin for junctional localization. J Cell Biol. 1998;140:1475-84 pubmed
immunoprecipitation; human immunocytochemistry; human western blot; human	Islam S, Carey T, Wolf G, Wheelock M, Johnson K. Expression of N-cadherin by human squamous carcinoma cells induces a scattered fibroblastic phenotype with disrupted cell-cell adhesion. J Cell Biol. 1996;135:1643-54 pubmed
immunocytochemistry; human	Peralta Soler A, Knudsen K, Jaurand M, Johnson K, Wheelock M, Klein Szanto A, et al. The differential expression of N-cadherin and E-cadherin distinguishes pleural mesotheliomas from lung adenocarcinomas. Hum Pathol. 1995;26:1363-9 pubmed
immunoprecipitation; human immunocytochemistry; human western blot; human	Knudsen K, Soler A, Johnson K, Wheelock M. Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin. J Cell Biol. 1995;130:67-77 pubmed
western blot; human	Sacco P, McGranahan T, Wheelock M, Johnson K. Identification of plakoglobin domains required for association with N-cadherin and alpha-catenin. J Biol Chem. 1995;270:20201-6 pubmed
	Belghasem M, Yin W, Lotfollahzadeh S, Yang X, Meyer R, Napoleon M, et al. Tryptophan Metabolites Target Transmembrane and Immunoglobulin Domain-Containing 1 Signaling to Augment Renal Tubular Injury. Am J Pathol. 2023;193:1501-1516 pubmed publisher
	x15a wierczewska M, Sterzy x144 ska K, Ruci x144 ski M, Andrzejewska M, Nowicki M, Januchowski R. The response and resistance to drugs in ovarian cancer cell lines in 2D monolayers and 3D spheroids. Biomed Pharmacother. 2023;165:115152 pubmed publisher
	Lin Y, Zhang F, Lei W, Gan X, Li M, Pan F, et al. Amnion-derived serum amyloid A1 participates in sterile inflammation of fetal membranes at parturition. Inflamm Res. 2023;72:797-812 pubmed publisher
	Donaldson R, Buchanan O, Graham T, Ross J. Development of a Novel Epidural Hemorrhage Model in Swine. Mil Med. 2023;188:20-26 pubmed publisher
	Huang M, Wang C, Yao Y, Li H, Yao Y, Zhu Y, et al. Mebendazole-Induced Blood-Testis Barrier Injury in Mice Testes by Disrupting Microtubules in Addition to Triggering Programmed Cell Death. Int J Mol Sci. 2022;23: pubmed publisher
	Karim S, Burzangi A, Ahmad A, Siddiqui N, Ibrahim I, Sharma P, et al. PI3K-AKT Pathway Modulation by Thymoquinone Limits Tumor Growth and Glycolytic Metabolism in Colorectal Cancer. Int J Mol Sci. 2022;23: pubmed publisher
	Prasad A, Mahmood A, Gupta R, Bisoyi P, Saleem N, Naga Prasad S, et al. In cardiac muscle cells, both adrenergic agonists and antagonists induce reactive oxygen species from NOX2 but mutually attenuate each other's effects. Eur J Pharmacol. 2021;908:174350 pubmed publisher
	Padder R, Bhat Z, Ahmad Z, Singh N, Husain M. DRP1 Promotes BRAFV600E-Driven Tumor Progression and Metabolic Reprogramming in Colorectal Cancer. Front Oncol. 2020;10:592130 pubmed publisher
	Matta R, Yousafzai M, Murrell M, Gonzalez A. Endothelial cell secreted metalloproteinase-2 enhances neural stem cell N-cadherin expression, clustering, and migration. FASEB J. 2021;35:e21311 pubmed publisher
	Sáenz de Santa María I, Celada L, San José Martínez A, Cubiella T, Chiara M. Blockage of Squamous Cancer Cell Collective Invasion by FAK Inhibition Is Released by CAFs and MMP-2. Cancers (Basel). 2020;12: pubmed publisher
	Beauchamp P, Jackson C, Ozhathil L, Agarkova I, Galindo C, Sawyer D, et al. 3D Co-culture of hiPSC-Derived Cardiomyocytes With Cardiac Fibroblasts Improves Tissue-Like Features of Cardiac Spheroids. Front Mol Biosci. 2020;7:14 pubmed publisher
	Mohammed S, Torres Luquis O, Walls E, Lloyd F. Lymph-circulating tumor cells show distinct properties to blood-circulating tumor cells and are efficient metastatic precursors. Mol Oncol. 2019;13:1400-1418 pubmed publisher
	Zhao K, Li X, Chen X, Zhu Q, Yin F, Ruan Q, et al. Inhibition of miR-140-3p or miR-155-5p by antagomir treatment sensitize chordoma cells to chemotherapy drug treatment by increasing PTEN expression. Eur J Pharmacol. 2019;854:298-306 pubmed publisher
	Ren W, Hou J, Yang C, Wang H, Wu S, Wu Y, et al. Extracellular vesicles secreted by hypoxia pre-challenged mesenchymal stem cells promote non-small cell lung cancer cell growth and mobility as well as macrophage M2 polarization via miR-21-5p delivery. J Exp Clin Cancer Res. 2019;38:62 pubmed publisher
	Chiba Y, He B, Yoshizaki K, Rhodes C, Ishijima M, Bleck C, et al. The transcription factor AmeloD stimulates epithelial cell motility essential for tooth morphology. J Biol Chem. 2019;294:3406-3418 pubmed publisher
	Park S, Kim H, Kim K, Roh S. Sonic hedgehog signalling regulates the self-renewal and proliferation of skin-derived precursor cells in mice. Cell Prolif. 2018;51:e12500 pubmed publisher
	Chen C, Melo E, Jakob P, Friedlein A, Elsässer B, Goettig P, et al. N-Terminomics identifies HtrA1 cleavage of thrombospondin-1 with generation of a proangiogenic fragment in the polarized retinal pigment epithelial cell model of age-related macular degeneration. Matrix Biol. 2018;70:84-101 pubmed publisher
	Melo E, Oertle P, Trepp C, Meistermann H, Burgoyne T, Sborgi L, et al. HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease Model. EBioMedicine. 2018;27:258-274 pubmed publisher
	Becker A, Qian J, Gelman B, Yang M, Bauer P, Koeppen A. Heart and Nervous System Pathology in Compound Heterozygous Friedreich Ataxia. J Neuropathol Exp Neurol. 2017;76:665-675 pubmed publisher
	Farjood F, Vargis E. Physical disruption of cell-cell contact induces VEGF expression in RPE cells. Mol Vis. 2017;23:431-446 pubmed
	Koeppen A, Becker A, Feustel P, Gelman B, Mazurkiewicz J. The significance of intercalated discs in the pathogenesis of Friedreich cardiomyopathy. J Neurol Sci. 2016;367:171-6 pubmed publisher
	Michelhaugh S, Guastella A, Varadarajan K, Klinger N, Parajuli P, Ahmad A, et al. Development of patient-derived xenograft models from a spontaneously immortal low-grade meningioma cell line, KCI-MENG1. J Transl Med. 2015;13:227 pubmed publisher
	Mialhe A, Levacher G, Champelovier P, Martel V, Serres M, Knudsen K, et al. Expression of E-, P-, n-cadherins and catenins in human bladder carcinoma cell lines. J Urol. 2000;164:826-35 pubmed
	Peralta Soler A, Knudsen K, Tecson Miguel A, McBrearty F, Han A, Salazar H. Expression of E-cadherin and N-cadherin in surface epithelial-stromal tumors of the ovary distinguishes mucinous from serous and endometrioid tumors. Hum Pathol. 1997;28:734-9 pubmed
	Han A, Peralta Soler A, Knudsen K, Wheelock M, Johnson K, Salazar H. Differential expression of N-cadherin in pleural mesotheliomas and E-cadherin in lung adenocarcinomas in formalin-fixed, paraffin-embedded tissues. Hum Pathol. 1997;28:641-5 pubmed
	Hazan R, Kang L, Whooley B, Borgen P. N-cadherin promotes adhesion between invasive breast cancer cells and the stroma. Cell Adhes Commun. 1997;4:399-411 pubmed

product information

master code :

NBP1-48309

SKU :

NBP1-48309

product name :

N-Cadherin Antibody (13A9) - BSA Free

unit size :

0.1 ml (also 0.025 ml)

description :

The N-Cadherin Antibody (13A9) - BSA Free from Novus is a mouse monoclonal antibody to N-Cadherin. This antibody reacts with human,mouse,rat. The N-Cadherin Antibody (13A9) - BSA Free has been validated for the following applications: Western Blot,Immunohistochemistry-Paraffin,IF/IHC,Simple Western,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Immunocytochemistry,Immunocytochemistry/ Immunofluorescence,Flow (Intracellular).

target :

N-Cadherin

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

13A9

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

This N-Cadherin Antibody (13A9) was developed against the cytoplasmic domain of human N Cadherin [Swiss-Prot# P19022].

isotype :

IgG1

purity :

Protein G purified

species :

Human,Mouse,Rat

theoretical molecular weight :

140 kDa

gene symbol :

CDH2

Antibody validation :

Biological Validation

accessionNumbers :

P19022

applications :

Western Blot,Immunohistochemistry-Paraffin,IF/IHC,Simple Western,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Immunocytochemistry,Immunocytochemistry/ Immunofluorescence,Flow (Intracellular)

USD :

449 USD

alt names :

ACOGS, ARVD14, cadherin 2, type 1, N-cadherin (neuronal), cadherin-2, calcium-dependent adhesion protein, neuronal, CD325, CD325 antigen, CDH2, CDHN, CDw325, NCAD, N-cadherin, N-cadherin 1, Neural cadherin, neural-cadherin

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage