product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Notch-1 Antibody (OTI3E12)
catalog :
NBP1-48289
quantity :
0.1 ml
price :
479 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OTI3E12
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 4
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
Stoyanova T, Riedinger M, Lin S, Faltermeier C, Smith B, Zhang K, et al. Activation of Notch1 synergizes with multiple pathways in promoting castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2016;113:E6457-E6466 pubmed
Nikoloudaki G, Basdeki E, Kerezoudis N, Tosios K. Notch-1/2 receptors and Jagged-1 ligand, but not HERP-1 transcription factor, are immunohistochemically expressed in the epithelial lining of periapical cysts. J Clin Exp Dent. 2024;16:e25-e31 pubmed publisher
Nagy N, Hajdu M, Márk A, Király P, Tóth M, Dankó T, et al. Growth inhibitory effect of rapamycin in Hodgkin-lymphoma cell lines characterized by constitutive NOTCH1 activation. Tumour Biol. 2016;37:13695-13704 pubmed
Groeneweg J, Hall T, Zhang L, Kim M, Byron V, Tambouret R, et al. Inhibition of gamma-secretase activity impedes uterine serous carcinoma growth in a human xenograft model. Gynecol Oncol. 2014;133:607-15 pubmed publisher
product information
master code :
NBP1-48289
SKU :
NBP1-48289
product name :
Notch-1 Antibody (OTI3E12)
unit size :
0.1 ml
description :
The Notch-1 Antibody (OTI3E12) from Novus is a mouse monoclonal antibody to Notch-1. This antibody reacts with human,mouse,rat. The Notch-1 Antibody (OTI3E12) has been validated for the following applications: Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry,Immunocytochemistry/ Immunofluorescence.
target :
Notch-1
category :
Primary Antibodies
buffer :
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
clonality :
Monoclonal
clone :
OTI3E12
concentration :
0.2 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Recombinant protein expressed in E.coli corresponding to amino acids 2300-2556 of human NOTCH1
isotype :
IgG2b
purity :
Immunogen affinity purified
species :
Human,Mouse,Rat
specificity :
This antibody is specific for Homo sapiens Notch homolog 1, translocation-associated (Drosophila) (NOTCH1)
theoretical molecular weight :
270.6 kDa
gene symbol :
NOTCH1
accessionNumbers :
P46531
applications :
Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry,Immunocytochemistry/ Immunofluorescence
USD :
479 USD
alt names :
EC 2.1.2.11, EC 3.4.21.68, hN1, Notch (Drosophila) homolog 1 (translocation-associated), notch 1Notch homolog 1, translocation-associated (Drosophila), Notch homolog 1, translocation-associated, TAN1neurogenic locus notch homolog protein 1, Translocation-associated notch protein TAN-1
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.