HES-1 Antibody (OTI4H1) | Novus Biologicals NBP1-47791 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

HES-1 Antibody (OTI4H1)

catalog :

NBP1-47791

quantity :

0.1 ml

price :

479 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

OTI4H1

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, chromatin immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 12

Reference
Kim M, Kang H, Baek J, Cho M, Chung E, Kim S, et al. Disrupting Notch signaling related HES1 in myeloid cells reinvigorates antitumor T cell responses. Exp Hematol Oncol. 2024;13:122 pubmed publisher
Wen T, Duan Y, Gao D, Zhang X, Zhang X, Liang L, et al. miR-342-5p promotes vascular smooth muscle cell phenotypic transition through a negative-feedback regulation of Notch signaling via targeting FOXO3. Life Sci. 2023;326:121828 pubmed publisher
Abe T, Uosaki H, Shibata H, Hara H, Sarentonglaga B, Nagao Y, et al. Fetal sheep support the development of hematopoietic cells in vivo from human induced pluripotent stem cells. Exp Hematol. 2021;95:46-57.e8 pubmed publisher
Winkler R, Gillis E, Lasman L, Safra M, Geula S, Soyris C, et al. m6A modification controls the innate immune response to infection by targeting type I interferons. Nat Immunol. 2019;20:173-182 pubmed publisher
Kim T, Jeong J, Park J, Kim S, Heo J, Kang H, et al. miR-150 enhances apoptotic and anti-tumor effects of paclitaxel in paclitaxel-resistant ovarian cancer cells by targeting Notch3. Oncotarget. 2017;8:72788-72800 pubmed publisher
Liao B, Zhou H, Liang H, Li C. Regulation of ERK and AKT pathways by hepatitis B virus X protein via the Notch1 pathway in hepatocellular carcinoma. Int J Oncol. 2017;51:1449-1459 pubmed publisher
Jeong J, Kang H, Kim T, Kim G, Heo J, Kwon A, et al. MicroRNA-136 inhibits cancer stem cell activity and enhances the anti-tumor effect of paclitaxel against chemoresistant ovarian cancer cells by targeting Notch3. Cancer Lett. 2017;386:168-178 pubmed publisher
Zhou J, Wan J, Gao X, Zhang X, Jaffrey S, Qian S. Dynamic m(6)A mRNA methylation directs translational control of heat shock response. Nature. 2015;526:591-4 pubmed publisher
Liu N, Dai Q, Zheng G, He C, Parisien M, Pan T. N(6)-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions. Nature. 2015;518:560-4 pubmed publisher
Chiou H, Liu S, Lin C, Lee E. Hes-1 SUMOylation by protein inhibitor of activated STAT1 enhances the suppressing effect of Hes-1 on GADD45? expression to increase cell survival. J Biomed Sci. 2014;21:53 pubmed publisher
Maraver A, Fernandez Marcos P, Herranz D, Muñoz Martin M, Gomez Lopez G, Canamero M, et al. Therapeutic effect of ?-secretase inhibition in KrasG12V-driven non-small cell lung carcinoma by derepression of DUSP1 and inhibition of ERK. Cancer Cell. 2012;22:222-34 pubmed publisher
Wang C, Wei Q, Han I, Sato S, Ghanbari Azarnier R, Whetstone H, et al. Hedgehog and Notch signaling regulate self-renewal of undifferentiated pleomorphic sarcomas. Cancer Res. 2012;72:1013-22 pubmed publisher

product information

master code :

NBP1-47791

SKU :

NBP1-47791

product name :

HES-1 Antibody (OTI4H1)

unit size :

0.1 ml

description :

The HES-1 Antibody (OTI4H1) from Novus is a mouse monoclonal antibody to HES-1. This antibody reacts with human,mouse,rat. The HES-1 Antibody (OTI4H1) has been validated for the following applications: Chemotaxis,IF/IHC,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry/ Immunofluorescence.

target :

HES-1

category :

Primary Antibodies

buffer :

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

clonality :

Monoclonal

clone :

OTI4H1

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Recombinant protein expressed in E.coli corresponding to amino acids 1-280 of human HES1

isotype :

IgG1

purity :

Immunogen affinity purified

species :

Human,Mouse,Rat

specificity :

This antibody is specific for Homo sapiens hairy and enhancer of split 1, (Drosophila) (HES1)

theoretical molecular weight :

29.4 kDa

gene symbol :

HES1

accessionNumbers :

Q14469

applications :

Chemotaxis,IF/IHC,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry/ Immunofluorescence

USD :

479 USD

alt names :

BHLHB39, bHLHb39hairy homolog (Drosophila), Class B basic helix-loop-helix protein 39, FLJ20408, Hairy and enhancer of split 1, hairy and enhancer of split 1, (Drosophila), Hairy homolog, Hairy-like protein, Hes1, HES-1, hHL, HL, HRYHHL, transcription factor HES-1

storage :

Store at -20C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage