product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
UBR2 Antibody
catalog :
NBP1-45243
quantity :
0.1 mg
price :
409 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
clone name :
1F8-3A8
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 10
Reference
Wu H, Trevino J, Fang B, Riner A, Vudatha V, Zhang G, et al. Patient-Derived Pancreatic Cancer Cells Induce C2C12 Myotube Atrophy by Releasing Hsp70 and Hsp90. Cells. 2022;11: pubmed publisher
Shi X, Yang J, Liu M, Zhang Y, Zhou Z, Luo W, et al. Circular RNA ANAPC7 Inhibits Tumor Growth and Muscle Wasting via PHLPP2-AKT-TGF-β Signaling Axis in Pancreatic Cancer. Gastroenterology. 2022;162:2004-2017.e2 pubmed publisher
Liu Z, Xiong J, Gao S, Zhu M, Sun K, Li M, et al. Ameliorating cancer cachexia by inhibiting cancer cell release of Hsp70 and Hsp90 with omeprazole. J Cachexia Sarcopenia Muscle. 2022;13:636-647 pubmed publisher
Sin T, Zhang G, Zhang Z, Zhu J, Zuo Y, Frost J, et al. Cancer-Induced Muscle Wasting Requires p38β MAPK Activation of p300. Cancer Res. 2021;81:885-897 pubmed publisher
Liu Z, Sin K, Ding H, Doan H, Gao S, Miao H, et al. p38β MAPK mediates ULK1-dependent induction of autophagy in skeletal muscle of tumor-bearing mice. Cell Stress. 2018;2:311-324 pubmed publisher
Sin T, Zhu J, Zhang G, Li Y. p300 Mediates Muscle Wasting in Lewis Lung Carcinoma. Cancer Res. 2019;79:1331-1342 pubmed publisher
Zhang G, Liu Z, Ding H, Zhou Y, Doan H, Sin K, et al. Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90. Nat Commun. 2017;8:589 pubmed publisher
Cha Molstad H, Yu J, Feng Z, Lee S, Kim J, Yang P, et al. p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis. Nat Commun. 2017;8:102 pubmed publisher
Zhang G, Liu Z, Ding H, Miao H, Garcia J, Li Y. Toll-like receptor 4 mediates Lewis lung carcinoma-induced muscle wasting via coordinate activation of protein degradation pathways. Sci Rep. 2017;7:2273 pubmed publisher
Ding H, Zhang G, Sin K, Liu Z, Lin R, Li M, et al. Activin A induces skeletal muscle catabolism via p38? mitogen-activated protein kinase. J Cachexia Sarcopenia Muscle. 2017;8:202-212 pubmed publisher
product information
master code :
NBP1-45243
SKU :
NBP1-45243
product name :
UBR2 Antibody
unit size :
0.1 mg
description :
The UBR2 Antibody from Novus is a goat polyclonal antibody to UBR2. This antibody reacts with human,mouse. The UBR2 Antibody has been validated for the following applications: Western Blot,Chemotaxis,Immunohistochemistry,Immunohistochemistry-Paraffin,Peptide ELISA.
target :
UBR2
category :
Primary Antibodies
buffer :
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
clonality :
Polyclonal
concentration :
0.5 mg/ml
conjugate :
Unconjugated
host :
Goat
immunogen :
Peptide with sequence SCPKSGGDKSRAPT corresponding to internal region according to NP_056070.1.
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse
gene symbol :
UBR2
accessionNumbers :
NP_056070.1
applications :
Western Blot,Chemotaxis,Immunohistochemistry,Immunohistochemistry-Paraffin,Peptide ELISA
USD :
409 USD
alt names :
bA49A4.1, C6orf133MGC71112, chromosome 6 open reading frame 133, dJ242G1.1, dJ392M17.3, DKFZp686C08114, E3 ubiquitin-protein ligase UBR2, EC 6.3.2.-, KIAA0349FLJ36357, N-recognin-2, RP3-392M17.3, ubiquitin protein ligase E3 component n-recognin 2, Ubiquitin-protein ligase E3-alpha-2, Ubiquitin-protein ligase E3-alpha-II
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.