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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
MHC class II (I-A/I-E) Antibody (M5/114.15.2) - BSA Free
catalog :
NBP1-43312-0.1mg
quantity :
0.1 mg (also 0.05 mg, 0.5 mg)
price :
399 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
M5/114.15.2
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 21
Reference
Gallage S, Ali A, Barragan Avila J, Seymen N, Ramadori P, Joerke V, et al. A 5:2 intermittent fasting regimen ameliorates NASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1. Cell Metab. 2024;36:1371-1393.e7 pubmed publisher
Luckett T, Abudula M, Ireland L, Glenn M, Bellomo G, Stafferton R, et al. Mesothelin Secretion by Pancreatic Cancer Cells Co-opts Macrophages and Promotes Metastasis. Cancer Res. 2024;84:527-544 pubmed publisher
Funk M, Gleixner J, Heigwer F, Vonficht D, Valentini E, Aydin Z, et al. Aged intestinal stem cells propagate cell-intrinsic sources of inflammaging in mice. Dev Cell. 2023;58:2914-2929.e7 pubmed publisher
Nithianandam V, Bukhari H, Leventhal M, Battaglia R, Dong X, Fraenkel E, et al. Integrative analysis reveals a conserved role for the amyloid precursor protein in proteostasis during aging. Nat Commun. 2023;14:7034 pubmed publisher
Xiao J, Huang J, Jian X, Wang H, Lan H, Liao Z, et al. IRE1α arm of unfolded protein response in muscle-specific TGF-β signaling-mediated regulation of muscle cell immunological properties. Cell Mol Biol Lett. 2023;28:15 pubmed publisher
Tanaka T, Okuda H, Isonishi A, Terada Y, Kitabatake M, Shinjo T, et al. Dermal macrophages set pain sensitivity by modulating the amount of tissue NGF through an SNX25-Nrf2 pathway. Nat Immunol. 2023;24:439-451 pubmed publisher
Balmert S, Ghozloujeh Z, Carey C, Williams L, Zhang J, Shahi P, et al. A microarray patch SARS-CoV-2 vaccine induces sustained antibody responses and polyfunctional cellular immunity. iScience. 2022;25:105045 pubmed publisher
Sobel R, Albertelli M, Hinojoza J, Eaton M, Grimes K, Rubenstein E. Azetidine-2-Carboxylic Acid-Induced Oligodendrogliopathy: Relevance to the Pathogenesis of Multiple Sclerosis. J Neuropathol Exp Neurol. 2022;81:414-433 pubmed publisher
Rohlfing A, Kolb K, Sigle M, Ziegler M, Bild A, M xfc nzer P, et al. ACKR3 regulates platelet activation and ischemia-reperfusion tissue injury. Nat Commun. 2022;13:1823 pubmed publisher
Deczkowska A, David E, Ramadori P, Pfister D, Safran M, At The B, et al. XCR1+ type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis. Nat Med. 2021;27:1043-1054 pubmed publisher
Simion V, Zhou H, Haemmig S, Pierce J, Mendes S, Tesmenitsky Y, et al. A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus. Nat Commun. 2020;11:6135 pubmed publisher
Pires A, Greenshields Watson A, Jones E, Smart K, Lauder S, Somerville M, et al. Immune Remodeling of the Extracellular Matrix Drives Loss of Cancer Stem Cells and Tumor Rejection. Cancer Immunol Res. 2020;8:1520-1531 pubmed publisher
Feldmann K, Maurer C, Peschke K, Teller S, Schuck K, Steiger K, et al. Mesenchymal Plasticity Regulated by Prrx1 Drives Aggressive Pancreatic Cancer Biology. Gastroenterology. 2021;160:346-361.e24 pubmed publisher
Hoefflin R, Harlander S, Schäfer S, Metzger P, Kuo F, Schönenberger D, et al. HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice. Nat Commun. 2020;11:4111 pubmed publisher
Loffredo Verde E, Bhattacharjee S, Malo A, Festag J, Kosinska A, Ringelhan M, et al. Dynamic, Helminth-Induced Immune Modulation Influences the Outcome of Acute and Chronic Hepatitis B Virus Infection. J Infect Dis. 2020;221:1448-1461 pubmed publisher
Guerrero A, Herranz N, Sun B, Wagner V, Gallage S, Guiho R, et al. Cardiac glycosides are broad-spectrum senolytics. Nat Metab. 2019;1:1074-1088 pubmed publisher
O CONNOR T, Zhou X, Kosla J, Adili A, García Beccaria M, Kotsiliti E, et al. Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention. Cancer Cell. 2019;36:250-267.e9 pubmed publisher
Seehawer M, Heinzmann F, D Artista L, Harbig J, Roux P, Hoenicke L, et al. Necroptosis microenvironment directs lineage commitment in liver cancer. Nature. 2018;562:69-75 pubmed publisher
Georgilis A, Klotz S, Hanley C, Herranz N, Weirich B, Morancho B, et al. PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells. Cancer Cell. 2018;34:85-102.e9 pubmed publisher
Matsuzaka Y, Tanihata J, Komaki H, Ishiyama A, Oya Y, Ruegg U, et al. Characterization and Functional Analysis of Extracellular Vesicles and Muscle-Abundant miRNAs (miR-1, miR-133a, and miR-206) in C2C12 Myocytes and mdx Mice. PLoS ONE. 2016;11:e0167811 pubmed publisher
Huang L, Wohlleber D, Reisinger F, Jenne C, Cheng R, Abdullah Z, et al. Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection. Nat Immunol. 2013;14:574-83 pubmed publisher
product information
master code :
NBP1-43312
SKU :
NBP1-43312-0.1mg
product name :
MHC class II (I-A/I-E) Antibody (M5/114.15.2) - BSA Free
unit size :
0.1 mg (also 0.05 mg, 0.5 mg)
description :
The MHC class II (I-A/I-E) Antibody (M5/114.15.2) - BSA Free from Novus is a rat monoclonal antibody to MHC class II (I-A/I-E). This antibody reacts with human,mouse. The MHC class II (I-A/I-E) Antibody (M5/114.15.2) - BSA Free has been validated for the following applications: Immunohistochemistry,IF/IHC,Flow Cytometry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen.
target :
MHC class II (I-A/I-E)
category :
Primary Antibodies
buffer :
PBS (pH 7.2)
clonality :
Monoclonal
clone :
M5/114.15.2
concentration :
0.5 mg/ml
conjugate :
Unconjugated
host :
Rat
immunogen :
The immunogen for this antibody was MHC Class II.
isotype :
IgG2b Kappa
purity :
Protein A or G purified
species :
Human,Mouse
specificity :
The monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s)
gene symbol :
H2-Ea
applications :
Immunohistochemistry,IF/IHC,Flow Cytometry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen
USD :
399 USD
alt names :
E-alpha-f;H-2 class II histocompatibility antigen, E-K alpha chain;H-2 class II histocompatibility antigen, E-U alpha chain;H-2E;H2-Ea;H-2Ea;H2-Ea-ps;I;Ia;Ia3;Ia-3;I-E;I-Ealpha;MHC-H2-Ea
storage :
Store at 4C. Do not freeze.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.