DNA Ligase III Antibody (1F3) - Azide and BSA Free | Novus Biologicals NBP1-41190 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

DNA Ligase III Antibody (1F3) - Azide and BSA Free

catalog :

NBP1-41190

quantity :

100 ul

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1F3

reactivity :

human, mouse, chicken

application :

western blot, immunocytochemistry, neutralization, immunoprecipitation, proximity ligation assay

more info or order :

Novus Biologicals product webpage

citations: 10

Reference
Ebert F, Weiss A, Bültemeyer M, Hamann I, Hartwig A, Schwerdtle T. Arsenicals affect base excision repair by several mechanisms. Mutat Res. 2011;715:32-41 pubmed publisher
Singh S, Wu W, Zhang L, Klammer H, Wang M, Iliakis G. Widespread dependence of backup NHEJ on growth state: ramifications for the use of DNA-PK inhibitors. Int J Radiat Oncol Biol Phys. 2011;79:540-8 pubmed publisher
Asagoshi K, Liu Y, Masaoka A, Lan L, Prasad R, Horton J, et al. DNA polymerase beta-dependent long patch base excision repair in living cells. DNA Repair (Amst). 2010;9:109-19 pubmed publisher
Guo Z, Zheng L, Dai H, Zhou M, Xu H, Shen B. Human DNA polymerase beta polymorphism, Arg137Gln, impairs its polymerase activity and interaction with PCNA and the cellular base excision repair capacity. Nucleic Acids Res. 2009;37:3431-41 pubmed publisher
Chen X, Zhong S, Zhu X, Dziegielewska B, Ellenberger T, Wilson G, et al. Rational design of human DNA ligase inhibitors that target cellular DNA replication and repair. Cancer Res. 2008;68:3169-77 pubmed publisher
Windhofer F, Wu W, Iliakis G. Low levels of DNA ligases III and IV sufficient for effective NHEJ. J Cell Physiol. 2007;213:475-83 pubmed
Dong Z, Tomkinson A. ATM mediates oxidative stress-induced dephosphorylation of DNA ligase IIIalpha. Nucleic Acids Res. 2006;34:5721-279 pubmed
Wang H, Rosidi B, Perrault R, Wang M, Zhang L, Windhofer F, et al. DNA ligase III as a candidate component of backup pathways of nonhomologous end joining. Cancer Res. 2005;65:4020-30 pubmed
Okano S, Lan L, Tomkinson A, Yasui A. Translocation of XRCC1 and DNA ligase IIIalpha from centrosomes to chromosomes in response to DNA damage in mitotic human cells. Nucleic Acids Res. 2005;33:422-9 pubmed
Leppard J, Dong Z, Mackey Z, Tomkinson A. Physical and functional interaction between DNA ligase IIIalpha and poly(ADP-Ribose) polymerase 1 in DNA single-strand break repair. Mol Cell Biol. 2003;23:5919-27 pubmed

product information

master code :

NBP1-41190

SKU :

NBP1-41190

product name :

DNA Ligase III Antibody (1F3) - Azide and BSA Free

unit size :

100 ul

description :

The DNA Ligase III Antibody (1F3) - Azide and BSA Free from Novus is a mouse monoclonal antibody to DNA Ligase III. This antibody reacts with chicken,human,mouse. The DNA Ligase III Antibody (1F3) - Azide and BSA Free has been validated for the following applications: Western Blot,Block/Neutralize,Immunoprecipitation,Proximity Ligation Assay,Immunocytochemistry/ Immunofluorescence.

target :

DNA Ligase III

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

1F3

conjugate :

Unconjugated

host :

Mouse

immunogen :

Recombinant full-length human DNA Ligase III-b.

isotype :

IgG1

purity :

Protein G purified

species :

Chicken,Human,Mouse

specificity :

This antibody will recognize human DNA ligase III

theoretical molecular weight :

113 kDa

gene symbol :

LIG3

applications :

Western Blot,Block/Neutralize,Immunoprecipitation,Proximity Ligation Assay,Immunocytochemistry/ Immunofluorescence

USD :

459 USD

alt names :

DNA ligase 3, DNA ligase III, EC 6.5.1.1, LIG2, ligase II, DNA, ATP-dependent, ligase III, DNA, ATP-dependent, Polydeoxyribonucleotide synthase [ATP] 3

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage