product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
BRCA1 Antibody (8F7) - Azide and BSA Free
catalog :
NBP1-41186
quantity :
100 ul
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
8F7
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 10
Reference
Guo Y, Chomiak A, Hong Y, Lowe C, Kopsidas C, Chan W, et al. Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration. iScience. 2022;25:104519 pubmed publisher
Chomiak A, Guo Y, Kopsidas C, McDaniel D, Lowe C, Pan H, et al. Nde1 is required for heterochromatin compaction and stability in neocortical neurons. iScience. 2022;25:104354 pubmed publisher
Turner N, Lord C, Iorns E, Brough R, Swift S, Elliott R, et al. A synthetic lethal siRNA screen identifying genes mediating sensitivity to a PARP inhibitor. EMBO J. 2008;27:1368-77 pubmed publisher
Lee M, Tseng R, Hsu H, Chen J, Tzao C, Ho W, et al. Epigenetic inactivation of the chromosomal stability control genes BRCA1, BRCA2, and XRCC5 in non-small cell lung cancer. Clin Cancer Res. 2007;13:832-8 pubmed
Al Mulla F, Abdulrahman M, Varadharaj G, Akhter N, Anim J. BRCA1 gene expression in breast cancer: a correlative study between real-time RT-PCR and immunohistochemistry. J Histochem Cytochem. 2005;53:621-9 pubmed
Bernard Gallon D, Dechelotte P, Le Corre L, Chalabi N, Vissac Sabatier C, Bignon Y. Differential expressions of BRCA1 and BRCA2 in infantile gynecomastia. Anticancer Res. 2004;24:321-4 pubmed
Ongusaha P, Ouchi T, Kim K, Nytko E, Kwak J, Duda R, et al. BRCA1 shifts p53-mediated cellular outcomes towards irreversible growth arrest. Oncogene. 2003;22:3749-58 pubmed
Reed W, Sandstad B, Holm R, Nesland J. The prognostic impact of hormone receptors and c-erbB-2 in pregnancy-associated breast cancer and their correlation with BRCA1 and cell cycle modulators. Int J Surg Pathol. 2003;11:65-74 pubmed
Okada S, Ouchi T. Cell cycle differences in DNA damage-induced BRCA1 phosphorylation affect its subcellular localization. J Biol Chem. 2003;278:2015-20 pubmed
Bernard Gallon D, Dechelotte P, Vissac C, Aunoble B, Cravello L, Malpuech G, et al. BRCA1 and BRCA2 protein expressions in an ovotestis of a 46, XX true hermaphrodite. Breast Cancer Res. 2001;3:61-5 pubmed
product information
master code :
NBP1-41186
SKU :
NBP1-41186
product name :
BRCA1 Antibody (8F7) - Azide and BSA Free
unit size :
100 ul
description :
The BRCA1 Antibody (8F7) - Azide and BSA Free from Novus is a mouse monoclonal antibody to BRCA1. This antibody reacts with human,mouse. The BRCA1 Antibody (8F7) - Azide and BSA Free has been validated for the following applications: Immunohistochemistry,IF/IHC,Western Blot,Immunoprecipitation,Immunohistochemistry-Paraffin.
target :
BRCA1
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
8F7
conjugate :
Unconjugated
host :
Mouse
immunogen :
Protein fragment expressed in E. coli corresponding to amino acids 341-748.
isotype :
IgG1
purity :
Protein G purified
species :
Human,Mouse
theoretical molecular weight :
208 kDa
gene symbol :
BRCA1
Antibody validation :
Knockout/Knockdown
accessionNumbers :
P38398
applications :
IF/IHC,Western Blot,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin
USD :
469 USD
alt names :
BRCAI, breast and ovarian cancer susceptibility protein 1, breast and ovarian cancer sususceptibility protein, breast cancer 1, early onset, breast cancer type 1 susceptibility protein, EC 6.3.2, EC 6.3.2.-, IRIS, PNCA4, PSCP, subunit 1
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.