product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Adenosine A2aR Antibody (7F6-G5-A2) - BSA Free
catalog :
NBP1-39474
quantity :
0.1 ml (also 0.025 ml)
price :
479 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
7F6-G5-A2
reactivity :
human, mouse, rat, dogs
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 42
Reference
Allard B, Jacoberger Foissac C, Cousineau I, Bareche Y, Buisseret L, Chrobak P, et al. Adenosine A2A receptor is a tumor suppressor of NASH-associated hepatocellular carcinoma. Cell Rep Med. 2023;4:101188 pubmed publisher
Tokano M, Matsushita S, Takagi R, Yamamoto T, Kawano M. Extracellular adenosine induces hypersecretion of IL-17A by T-helper 17 cells through the adenosine A2a receptor. Brain Behav Immun Health. 2022;26:100544 pubmed publisher
Baum N, Fliegert R, Bauche A, Hambach J, Menzel S, Haag F, et al. Daratumumab and Nanobody-Based Heavy Chain Antibodies Inhibit the ADPR Cyclase but not the NAD+ Hydrolase Activity of CD38-Expressing Multiple Myeloma Cells. Cancers (Basel). 2020;13: pubmed publisher
Ott M, Tomaszowski K, Marisetty A, Kong L, Wei J, Duna M, et al. Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration. JCI Insight. 2020;5: pubmed publisher
Wen S, Li S, Li L, Fan Q. circACTR2: A Novel Mechanism Regulating High Glucose-Induced Fibrosis in Renal Tubular Cells via Pyroptosis. Biol Pharm Bull. 2020;43:558-564 pubmed publisher
Wen S, Wang Z, Zhang C, Yang Y, Fan Q. Caspase-3 Promotes Diabetic Kidney Disease Through Gasdermin E-Mediated Progression to Secondary Necrosis During Apoptosis. Diabetes Metab Syndr Obes. 2020;13:313-323 pubmed publisher
Basu M, Gupta P, Dutta A, Jana K, Ukil A. Increased host ATP efflux and its conversion to extracellular adenosine is crucial for establishing Leishmania infection. J Cell Sci. 2020;133: pubmed publisher
Sharma S, Plotkin M. Id1 expression in kidney endothelial cells protects against diabetes-induced microvascular injury. FEBS Open Bio. 2020;: pubmed publisher
He X, Chen S, Li C, Ban J, Wei Y, He Y, et al. Trehalose Alleviates Crystalline Silica-Induced Pulmonary Fibrosis via Activation of the TFEB-Mediated Autophagy-Lysosomal System in Alveolar Macrophages. Cells. 2020;9: pubmed publisher
Hernandez H, Roberts A, McDowell C. Nuclear factor-kappa beta signaling is required for transforming growth factor Beta-2 induced ocular hypertension. Exp Eye Res. 2020;191:107920 pubmed publisher
Fu C, Lu Y, Williams M, Brantly M, Ventetuolo C, MOREL L, et al. Emergency myelopoiesis contributes to immune cell exhaustion and pulmonary vascular remodelling. Br J Pharmacol. 2019;: pubmed publisher
Landry N, Rattan S, Dixon I. An Improved Method of Maintaining Primary Murine Cardiac Fibroblasts in Two-Dimensional Cell Culture. Sci Rep. 2019;9:12889 pubmed publisher
Barreto R, Romagnolli P, Fratini P, Mess A, Miglino M. Mouse placental scaffolds: a three-dimensional environment model for recellularization. J Tissue Eng. 2019;10:2041731419867962 pubmed publisher
Xu L, Sharkey D, Cantley L. Tubular GM-CSF Promotes Late MCP-1/CCR2-Mediated Fibrosis and Inflammation after Ischemia/Reperfusion Injury. J Am Soc Nephrol. 2019;: pubmed publisher
Borghesi J, da Silva Ferreira H, Oliveira Favaron P, Mario L, de Almeida da Anunciação A, Oliveira F, et al. Characterization of the extracellular matrix in the chorioallantoic membrane of water buffalo (Bubalus bubalis) in early gestation. Reprod Domest Anim. 2019;54:1313-1321 pubmed publisher
Lin X, Chai G, Wu Y, Li J, Chen F, Liu J, et al. RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail. Nat Commun. 2019;10:2065 pubmed publisher
Zheng M, Cai J, Liu Z, Shu S, Wang Y, Tang C, et al. Nicotinamide reduces renal interstitial fibrosis by suppressing tubular injury and inflammation. J Cell Mol Med. 2019;23:3995-4004 pubmed publisher
Zha D, Yao T, Bao L, Gao P, Wu X. Telmisartan attenuates diabetic nephropathy progression by inhibiting the dimerization of angiotensin type-1 receptor and adiponectin receptor-1. Life Sci. 2019;221:109-120 pubmed publisher
da Palma R, Fratini P, Schiavo Matias G, Cereta A, Guimaraes L, Anunciação A, et al. Equine lung decellularization: a potential approach for in vitro modeling the role of the extracellular matrix in asthma. J Tissue Eng. 2018;9:2041731418810164 pubmed publisher
Matias G, Rigoglio N, Carreira A, Romagnolli P, Barreto R, Mess A, et al. Optimization of Canine Placenta Decellularization: An Alternative Source of Biological Scaffolds for Regenerative Medicine. Cells Tissues Organs. 2018;205:217-225 pubmed publisher
Bao H, Sin T, Zhang G. Activin A induces leiomyoma cell proliferation, extracellular matrix (ECM) accumulation and myofibroblastic transformation of myometrial cells via p38 MAPK. Biochem Biophys Res Commun. 2018;504:447-453 pubmed publisher
Eissa L, Kenawy H, El Karef A, Elsherbiny N, El Mihi K. Antioxidant and anti-inflammatory activities of berberine attenuate hepatic fibrosis induced by thioacetamide injection in rats. Chem Biol Interact. 2018;294:91-100 pubmed publisher
Davis L, Musso J, Soman D, Louey S, Nelson J, Jonker S. Role of adenosine signaling in coordinating cardiomyocyte function and coronary vascular growth in chronic fetal anemia. Am J Physiol Regul Integr Comp Physiol. 2018;315:R500-R508 pubmed publisher
Chimote A, Balajthy A, Arnold M, Newton H, Hajdu P, Qualtieri J, et al. A defect in KCa3.1 channel activity limits the ability of CD8+ T cells from cancer patients to infiltrate an adenosine-rich microenvironment. Sci Signal. 2018;11: pubmed publisher
Jung M, Kang J, Hernandez D, Yin X, Andrianifahanana M, Wang Y, et al. Fatty acid synthase is required for profibrotic TGF-β signaling. FASEB J. 2018;32:3803-3815 pubmed publisher
Hirata Y, Furuhashi K, Ishii H, Li H, Pinho S, Ding L, et al. CD150high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine. Cell Stem Cell. 2018;22:445-453.e5 pubmed publisher
Graubner F, Boos A, Aslan S, Kücükaslan I, Kowalewski M. Uterine and placental distribution of selected extracellular matrix (ECM) components in the dog. Reproduction. 2018;155:403-421 pubmed publisher
da Silva Nunes Barreto R, Romagnolli P, Mess A, Miglino M. Decellularized bovine cotyledons may serve as biological scaffolds with preserved vascular arrangement. J Tissue Eng Regen Med. 2017;: pubmed publisher
Chiang K, Yeh C, Pang J, Hsu J, Yeh T, Chen L, et al. 1?,25(OH)2D3 Analog, MART-10, Inhibits Neuroendocrine Tumor Cell Metastasis After VEGF-A Stimulation. Anticancer Res. 2017;37:6215-6221 pubmed
El Mihi K, Kenawy H, El Karef A, Elsherbiny N, Eissa L. Naringin attenuates thioacetamide-induced liver fibrosis in rats through modulation of the PI3K/Akt pathway. Life Sci. 2017;187:50-57 pubmed publisher
Mediavilla Varela M, Castro J, Chiappori A, Noyes D, Hernandez D, Allard B, et al. A Novel Antagonist of the Immune Checkpoint Protein Adenosine A2a Receptor Restores Tumor-Infiltrating Lymphocyte Activity in the Context of the Tumor Microenvironment. Neoplasia. 2017;19:530-536 pubmed publisher
Sui B, Hu C, Zheng C, Shuai Y, He X, Gao P, et al. Recipient Glycemic Micro-environments Govern Therapeutic Effects of Mesenchymal Stem Cell Infusion on Osteopenia. Theranostics. 2017;7:1225-1244 pubmed publisher
Fu M, Song Y, Wen Z, Lu X, Cui L. Inositol Hexaphosphate and Inositol Inhibit Colorectal Cancer Metastasis to the Liver in BALB/c Mice. Nutrients. 2016;8: pubmed publisher
Nitta K, Shi S, Nagai T, Kanasaki M, Kitada M, Srivastava S, et al. Oral Administration of N-Acetyl-seryl-aspartyl-lysyl-proline Ameliorates Kidney Disease in Both Type 1 and Type 2 Diabetic Mice via a Therapeutic Regimen. Biomed Res Int. 2016;2016:9172157 pubmed publisher
Clancy Thompson E, Perekslis T, Croteau W, Alexander M, Chabanet T, Turk M, et al. Melanoma Induces, and Adenosine Suppresses, CXCR3-Cognate Chemokine Production and T-cell Infiltration of Lungs Bearing Metastatic-like Disease. Cancer Immunol Res. 2015;3:956-67 pubmed publisher
Del Ry S, Moscato S, Bianchi F, Morales M, Dolfi A, Burchielli S, et al. Altered expression of connexin 43 and related molecular partners in a pig model of left ventricular dysfunction with and without dipyrydamole therapy. Pharmacol Res. 2015;95-96:92-101 pubmed publisher
Green C, Fraser S, Day M. Insulin-like growth factor 1 increases apical fibronectin in blastocysts to increase blastocyst attachment to endometrial epithelial cells in vitro. Hum Reprod. 2015;30:284-98 pubmed publisher
Ribeiro A, Fernandes V, Orensanz L, Martínez M, Recio P, Martínez Saénz A, et al. Mechanisms involved in the adenosine-induced vasorelaxation to the pig prostatic small arteries. Purinergic Signal. 2011;7:413-25 pubmed publisher
Block E, Cronstein B. Interferon-gamma inhibits adenosine A2A receptor function in hepatic stellate cells by STAT1-mediated repression of adenylyl cyclase. Int J Interferon Cytokine Mediat Res. 2010;2010:113-126 pubmed
Haschemi A, Wagner O, Marculescu R, Wegiel B, Robson S, Gagliani N, et al. Cross-regulation of carbon monoxide and the adenosine A2a receptor in macrophages. J Immunol. 2007;178:5921-9 pubmed
Nguyen D, Montesinos M, Williams A, Kelly M, Cronstein B. Th1 cytokines regulate adenosine receptors and their downstream signaling elements in human microvascular endothelial cells. J Immunol. 2003;171:3991-8 pubmed
Khoa N, Montesinos M, Reiss A, Delano D, Awadallah N, Cronstein B. Inflammatory cytokines regulate function and expression of adenosine A(2A) receptors in human monocytic THP-1 cells. J Immunol. 2001;167:4026-32 pubmed
product information
master code :
NBP1-39474
SKU :
NBP1-39474
product name :
Adenosine A2aR Antibody (7F6-G5-A2) - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The Adenosine A2aR Antibody (7F6-G5-A2) - BSA Free from Novus is a mouse monoclonal antibody to Adenosine A2aR. This antibody reacts with canine,guinea pig,human,mouse,ovine,porcine,rabbit,rat,sheep. The Adenosine A2aR Antibody (7F6-G5-A2) - BSA Free has been validated for the following applications: Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry,Flow Cytometry,IF/IHC,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin,Flow (Intracellular),CyTOF-ready.
target :
Adenosine A2aR
category :
Primary Antibodies
buffer :
PBS
clonality :
Monoclonal
clone :
7F6-G5-A2
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Mouse
immunogen :
Full length recombinant human Adenosine A2a R. [UniProt# P29274]
isotype :
IgG2a
purity :
Protein G purified
species :
Canine,Guinea Pig,Human,Mouse,Ovine,Porcine,Rabbit,Rat,Sheep
theoretical molecular weight :
43 kDa
gene symbol :
ADORA2A
accessionNumbers :
P29274, P30543, Q60613
applications :
Flow Cytometry,IF/IHC,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin,Flow (Intracellular),CyTOF-ready
USD :
479 USD
alt names :
adenosine A2 receptor, adenosine A2a receptor, adenosine receptor A2a, adenosine receptor subtype A2a, ADORA 2, ADORA2, hA2aR, RDC8
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.