product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Lysyl Oxidase Homolog 2/LOXL2 Antibody - BSA Free
catalog :
NBP1-32954
quantity :
0.1 ml (also 0.025 ml)
price :
479 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
CB19
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 18
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:250–1:500
Rickelt S, Hynes R. Antibodies and methods for immunohistochemistry of extracellular matrix proteins. Matrix Biol. 2018;71-72:10-27 pubmed publisher
Cetin M, Saatci Ö, Rezaeian A, Rao C, Beneker C, Sreenivas K, et al. A highly potent bi-thiazole inhibitor of LOX rewires collagen architecture and enhances chemoresponse in triple-negative breast cancer. Cell Chem Biol. 2024;31:1926-1941.e11 pubmed publisher
Yun H, Im H, Choe C, Roh S. Effect of LOXL2 on metastasis through remodeling of the cell surface matrix in non-small cell lung cancer cells. Gene. 2022;830:146504 pubmed publisher
Jiang C, Wang M, Yao W, Lv G, Liu X, Wang G. Comprehensive Analysis on Prognosis and Immune Infiltration of Lysyl Oxidase Family Members in Pancreatic Adenocarcinoma With Experimental Verification. Front Mol Biosci. 2022;9:778857 pubmed publisher
Novotny T, Eckhardt A, Doubková M, Knitlova J, Vondrášek D, Vanaskova E, et al. The possible role of hypoxia in the affected tissue of relapsed clubfoot. Sci Rep. 2022;12:4462 pubmed publisher
Yamamoto A, Saito T, Hosoya T, Kawahata K, Asano Y, Sato S, et al. Therapeutic effect of cyclin-dependent kinase 4/6 inhibitor on dermal fibrosis in murine models of systemic sclerosis. Arthritis Rheumatol. 2021;: pubmed publisher
Bharti A, Urs A, Kumar P. Significance of HIF-1α Expression and LOXL-2 Localization in Progression of Oral Squamous Cell Carcinoma. Asian Pac J Cancer Prev. 2021;22:341-347 pubmed publisher
Cebrià Costa J, Pascual Reguant L, Gonzalez Perez A, Serra Bardenys G, Querol J, Cosín M, et al. LOXL2-mediated H3K4 oxidation reduces chromatin accessibility in triple-negative breast cancer cells. Oncogene. 2020;39:79-121 pubmed publisher
Jeong Y, Park S, Mun S, Kwak S, Lee S, Oh H. Association between lysyl oxidase and fibrotic focus in relation with inflammation in breast cancer. Oncol Lett. 2018;15:2431-2440 pubmed publisher
Tjin G, White E, Faiz A, Sicard D, Tschumperlin D, Mahar A, et al. Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis. Dis Model Mech. 2017;10:1301-1312 pubmed publisher
Sato F, Seino Sudo R, Okada M, Sakai H, Yumoto T, Wachi H. Lysyl Oxidase Enhances the Deposition of Tropoelastin through the Catalysis of Tropoelastin Molecules on the Cell Surface. Biol Pharm Bull. 2017;40:1646-1653 pubmed publisher
Holla S, Prakhar P, Singh V, Karnam A, Mukherjee T, Mahadik K, et al. MUSASHI-Mediated Expression of JMJD3, a H3K27me3 Demethylase, Is Involved in Foamy Macrophage Generation during Mycobacterial Infection. PLoS Pathog. 2016;12:e1005814 pubmed publisher
Deaglio S, Vaisitti T, Billington R, Bergui L, Omede P, Genazzani A, et al. CD38/CD19: a lipid raft-dependent signaling complex in human B cells. Blood. 2007;109:5390-8 pubmed
Deaglio S, Vaisitti T, Bergui L, Bonello L, Horenstein A, Tamagnone L, et al. CD38 and CD100 lead a network of surface receptors relaying positive signals for B-CLL growth and survival. Blood. 2005;105:3042-50 pubmed
Deaglio S, Capobianco A, Bergui L, Dürig J, Morabito F, Duhrsen U, et al. CD38 is a signaling molecule in B-cell chronic lymphocytic leukemia cells. Blood. 2003;102:2146-55 pubmed
Musso T, Deaglio S, Franco L, Calosso L, Badolato R, Garbarino G, et al. CD38 expression and functional activities are up-regulated by IFN-gamma on human monocytes and monocytic cell lines. J Leukoc Biol. 2001;69:605-12 pubmed
Deaglio S, Canella D, Baj G, Arnulfo A, Waxman S, Malavasi F. Evidence of an immunologic mechanism behind the therapeutical effects of arsenic trioxide (As(2)O(3)) on myeloma cells. Leuk Res. 2001;25:227-35 pubmed
Zilber M, Gregory S, Mallone R, Deaglio S, Malavasi F, Charron D, et al. CD38 expressed on human monocytes: a coaccessory molecule in the superantigen-induced proliferation. Proc Natl Acad Sci U S A. 2000;97:2840-5 pubmed
product information
master code :
NBP1-32954
SKU :
NBP1-32954
product name :
Lysyl Oxidase Homolog 2/LOXL2 Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The Lysyl Oxidase Homolog 2/LOXL2 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to Lysyl Oxidase Homolog 2/LOXL2. This antibody reacts with feline,human,mouse. The Lysyl Oxidase Homolog 2/LOXL2 Antibody - BSA Free has been validated for the following applications: Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,IF/IHC,Knockdown Validated,ELISA,Knockout Validated,Immunocytochemistry/ Immunofluorescence.
target :
Lysyl Oxidase Homolog 2/LOXL2
category :
Primary Antibodies
buffer :
PBS, 20% Glycerol
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Recombinant protein encompassing a sequence within the center region of human Lysyl Oxidase Homolog 2/LOXL2. The exact sequence is proprietary.
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Feline,Human,Mouse
theoretical molecular weight :
87 kDa
gene symbol :
LOXL2
Antibody validation :
Knockout/Knockdown
accessionNumbers :
Q9Y4K0
applications :
Immunohistochemistry,Immunohistochemistry-Paraffin,IF/IHC,Western Blot,Knockdown Validated,ELISA,Knockout Validated,Immunocytochemistry/ Immunofluorescence
USD :
479 USD
alt names :
EC 1.4.3, EC 1.4.3.-, LOR2, lysyl oxidase homolog 2, lysyl oxidase related 2, lysyl oxidase-like 2, Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14, WS9-14
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.