product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
PSAT1 Antibody
catalog :
NBP1-32920
quantity :
0.1 ml
price :
459 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
Novus Biologicals product webpage
citations: 14
Reference
Papalazarou V, Newman A, Huerta Uribe A, Legrave N, Falcone M, Zhang T, et al. Phenotypic profiling of solute carriers characterizes serine transport in cancer. Nat Metab. 2023;5:2148-2168 pubmed publisher
Kim Y, Ju H, Yoo S, Jeong J, Heo J, Lee S, et al. Glutathione dynamics is a potential predictive and therapeutic trait for neoadjuvant chemotherapy response in bladder cancer. Cell Rep Med. 2023;4:101224 pubmed publisher
Lee G, Wong C, Cho A, West J, Crawford A, Russo G, et al. Serine synthesis pathway upregulated by E-cadherin is essential for the proliferation and metastasis of breast cancers. bioRxiv. 2023;: pubmed publisher
Wang K, Luo L, Fu S, Wang M, Wang Z, Dong L, et al. PHGDH arginine methylation by PRMT1 promotes serine synthesis and represents a therapeutic vulnerability in hepatocellular carcinoma. Nat Commun. 2023;14:1011 pubmed publisher
Jiang J, Chen H, Jin P, Zhou L, Peng L, Huang Z, et al. Targeting PSAT1 to mitigate metastasis in tumors with p53-72Pro variant. Signal Transduct Target Ther. 2023;8:65 pubmed publisher
Ji J, Cochrane D, Negri G, Colborne S, Spencer Miko S, Hoang L, et al. The proteome of clear cell ovarian carcinoma. J Pathol. 2022;258:325-338 pubmed publisher
Di Marcantonio D, Martinez E, Kanefsky J, Huhn J, Gabbasov R, Gupta A, et al. ATF3 coordinates serine and nucleotide metabolism to drive cell cycle progression in acute myeloid leukemia. Mol Cell. 2021;81:2752-2764.e6 pubmed publisher
Montrose D, Saha S, Foronda M, McNally E, Chen J, Zhou X, et al. Exogenous and Endogenous Sources of Serine Contribute to Colon Cancer Metabolism, Growth, and Resistance to 5-Fluorouracil. Cancer Res. 2021;81:2275-2288 pubmed publisher
Yoshimura Y. Increased error-free DNA repair gene expression through reprogramming in human iPS cells. Regen Ther. 2019;11:101-105 pubmed publisher
Jiang J, Zhang L, Chen H, Lei Y, Zhang T, Wang Y, et al. Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma. Autophagy. 2019;:1-17 pubmed publisher
Toonen L, Overzier M, Evers M, Leon L, van der Zeeuw S, Mei H, et al. Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model. Mol Neurodegener. 2018;13:31 pubmed publisher
Nicholls T, Nadalutti C, Motori E, Sommerville E, Gorman G, Basu S, et al. Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA. Mol Cell. 2018;69:9-23.e6 pubmed publisher
Maddocks O, Athineos D, Cheung E, Lee P, Zhang T, van den Broek N, et al. Modulating the therapeutic response of tumours to dietary serine and glycine starvation. Nature. 2017;544:372-376 pubmed publisher
Samanta D, Park Y, Andrabi S, Shelton L, Gilkes D, Semenza G. PHGDH Expression Is Required for Mitochondrial Redox Homeostasis, Breast Cancer Stem Cell Maintenance, and Lung Metastasis. Cancer Res. 2016;76:4430-42 pubmed publisher
product information
master code :
NBP1-32920
SKU :
NBP1-32920
product name :
PSAT1 Antibody
unit size :
0.1 ml
description :
The PSAT1 Antibody from Novus is a rabbit polyclonal antibody to PSAT1. This antibody reacts with human,mouse. The PSAT1 Antibody has been validated for the following applications: Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry,Knockdown Validated,Immunocytochemistry/ Immunofluorescence.
target :
PSAT1
category :
Primary Antibodies
buffer :
PBS, 1% BSA, 20% Glycerol
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Recombinant protein encompassing a sequence within the center region of human PSAT1. The exact sequence is proprietary.
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse
theoretical molecular weight :
40 kDa
gene symbol :
PSAT1
Antibody validation :
Knockout/Knockdown
applications :
Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry,Knockdown Validated,Immunocytochemistry/ Immunofluorescence
USD :
459 USD
alt names :
EC 2.6.1.52, EPIP, Phosphohydroxythreonine aminotransferase, phosphoserine aminotransferase, phosphoserine aminotransferase 1, PSAMGC1460, PSATendometrial progesterone-induced protein
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
Novus Biologicals product webpage
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.