PDK3 Antibody | Novus Biologicals NBP1-32581 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

PDK3 Antibody

catalog :

NBP1-32581

quantity :

0.1 ml

price :

459 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

JM10-66

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 5

Reference
Yang E, Do Y, Cheon S, Kim B, LING J, Cho M, et al. Andrographolide suppresses aerobic glycolysis and induces apoptotic cell death by inhibiting pyruvate dehydrogenase kinase 1 expression. Oncol Rep. 2023;49: pubmed publisher
x160 korja Mili x107 N, Dolinar K, Mi x161 K, Matkovi x10d U, Bizjak M, Pavlin M, et al. Suppression of Pyruvate Dehydrogenase Kinase by Dichloroacetate in Cancer and Skeletal Muscle Cells Is Isoform Specific and Partially Independent of HIF-1α. Int J Mol Sci. 2021;22: pubmed publisher
Schoonjans C, Joudiou N, Brusa D, Corbet C, Feron O, Gallez B. Acidosis-induced metabolic reprogramming in tumor cells enhances the anti-proliferative activity of the PDK inhibitor dichloroacetate. Cancer Lett. 2020;470:18-28 pubmed publisher
Hou X, Zhang L, Han L, Ge J, Ma R, Zhang X, et al. Differing roles of pyruvate dehydrogenase kinases during mouse oocyte maturation. J Cell Sci. 2015;128:2319-29 pubmed publisher
Ho N, Coomber B. Pyruvate dehydrogenase kinase expression and metabolic changes following dichloroacetate exposure in anoxic human colorectal cancer cells. Exp Cell Res. 2015;331:73-81 pubmed publisher

product information

master code :

NBP1-32581

SKU :

NBP1-32581

product name :

PDK3 Antibody

unit size :

0.1 ml

description :

The PDK3 Antibody from Novus is a rabbit polyclonal antibody to PDK3. This antibody reacts with human,mouse,squirrel,xenopus. The PDK3 Antibody has been validated for the following applications: Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin.

target :

PDK3

category :

Primary Antibodies

buffer :

PBS (pH 7), 20% Glycerol, 1% BSA

clonality :

Polyclonal

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Recombinant protein encompassing a sequence within the center region of human PDK3. The exact sequence is proprietary.

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Squirrel,Xenopus

theoretical molecular weight :

47 kDa

gene symbol :

PDK3

accessionNumbers :

Q15120

applications :

Western Blot,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Immunohistochemistry-Paraffin

USD :

459 USD

alt names :

EC 2.7.11.2, Pyruvate dehydrogenase kinase isoform 3, pyruvate dehydrogenase kinase, isoenzyme 3, pyruvate dehydrogenase kinase, isozyme 3, pyruvate dehydrogenase, lipoamide, kinase isozyme 3, mitochondrial

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage