product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
BRIP1/FANCJ Antibody - BSA Free
catalog :
NBP1-31883
quantity :
0.1 ml
price :
459 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
CL3118
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, proximity ligation assay
more info or order :
citations: 11
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; loading ...; fig 2d
Krzeptowski W, Chudy P, Sokołowski G, Zukowska M, Kusienicka A, Seretny A, et al. Proximity Ligation Assay Detection of Protein-DNA Interactions-Is There a Link between Heme Oxygenase-1 and G-quadruplexes?. Antioxidants (Basel). 2021;10: pubmed publisher
Egger T, Morano L, Blanchard M, Basbous J, Constantinou A. Spatial organization and functions of Chk1 activation by TopBP1 biomolecular condensates. Cell Rep. 2024;43:114064 pubmed publisher
Isik E, Shukla K, Pospisilova M, K xf6 nig C, Andrs M, Rao S, et al. MutSβ-MutLβ-FANCJ axis mediates the restart of DNA replication after fork stalling at cotranscriptional G4/R-loops. Sci Adv. 2024;10:eadk2685 pubmed publisher
Boavida A, Napolitano L, Santos D, Cortone G, Jegadesan N, Onesti S, et al. FANCJ DNA helicase is recruited to the replisome by AND-1 to ensure genome stability. EMBO Rep. 2024;: pubmed publisher
Yaneva D, Sparks J, Donsbach M, Zhao S, Weickert P, Bezalel Buch R, et al. The FANCJ helicase unfolds DNA-protein crosslinks to promote their repair. Mol Cell. 2023;83:43-56.e10 pubmed publisher
Summers P, Lewis B, Gonzalez Garcia J, Porreca R, Lim A, Cadinu P, et al. Visualising G-quadruplex DNA dynamics in live cells by fluorescence lifetime imaging microscopy. Nat Commun. 2021;12:162 pubmed publisher
Rohn F, Kordes C, Buschmann T, Reichert D, Wammers M, Poschmann G, et al. Impaired integrin α5 /β1 -mediated hepatocyte growth factor release by stellate cells of the aged liver. Aging Cell. 2020;19:e13131 pubmed publisher
Liu P, Chen H, Yan L, Sun Y. Laminin α5 modulates fibroblast proliferation in epidural fibrosis through the PI3K/AKT/mTOR signaling pathway. Mol Med Rep. 2020;21:1491-1500 pubmed publisher
Gordon Weeks A, Lim S, Yuzhalin A, Lucotti S, Vermeer J, Jones K, et al. Tumour-Derived Laminin α5 (LAMA5) Promotes Colorectal Liver Metastasis Growth, Branching Angiogenesis and Notch Pathway Inhibition. Cancers (Basel). 2019;11: pubmed publisher
Kim D, Liu Y, Oberly S, Freire R, Smolka M. ATR-mediated proteome remodeling is a major determinant of homologous recombination capacity in cancer cells. Nucleic Acids Res. 2018;46:8311-8325 pubmed publisher
Sun X, Brieño Enríquez M, Cornelius A, Modzelewski A, Maley T, Campbell Peterson K, et al. FancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in mice. Chromosoma. 2016;125:237-52 pubmed publisher
product information
master code :
NBP1-31883
SKU :
NBP1-31883
product name :
BRIP1/FANCJ Antibody - BSA Free
unit size :
0.1 ml
description :
The BRIP1/FANCJ Antibody - BSA Free from Novus is a rabbit polyclonal antibody to BRIP1/FANCJ. This antibody reacts with human,mouse. The BRIP1/FANCJ Antibody - BSA Free has been validated for the following applications: Western Blot,Simple Western,Proximity Ligation Assay,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence.
target :
BRIP1/FANCJ
category :
Primary Antibodies
buffer :
PBS, 20% Glycerol
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Recombinant protein encompassing a sequence within the N-terminus region of human BRIP1/FANCJ. The exact sequence is proprietary.
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse
theoretical molecular weight :
141 kDa
gene symbol :
BRIP1
Antibody validation :
Orthogonal Validation
applications :
Simple Western,Proximity Ligation Assay,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence
USD :
459 USD
alt names :
ATP-dependent RNA helicase BRIP1, BACH1BRCA1/BRCA2-associated helicase 1, BRCA1 interacting protein C-terminal helicase 1, BRCA1-associated C-terminal helicase 1, BRCA1-binding helicase-like protein BACH1, BRCA1-interacting protein 1, BRCA1-interacting protein C-terminal helicase 1, EC 3.6.1, EC 3.6.4.13, FANCJFanconi anemia group J protein, FLJ90232, MGC126521, MGC126523, OF, Protein FACJ
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.