product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
NOX1 Antibody - BSA Free
catalog :
NBP1-31546
quantity :
100 ul
price :
449 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 41
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 6c
Pan C, Jin L, Wang X, Li Y, Chun J, Boese A, et al. Inositol-triphosphate 3-kinase B confers cisplatin resistance by regulating NOX4-dependent redox balance. J Clin Invest. 2019;129:2431-2445 pubmed publisher
Scharmacher J, Wartenberg M, Sauer H. The pro-inflammatory signature of lipopolysaccharide in spontaneous contracting embryoid bodies differentiated from mouse embryonic stem cells. J Cell Mol Med. 2023;27:2045-2058 pubmed publisher
Yao G, Li H, Zuo X, Wang C, Xiao Y, Zhao Y, et al. Oscillatory shear stress promotes vein graft intimal hyperplasia via NADPH oxidase-related pathways. Front Surg. 2023;10:1073557 pubmed publisher
Meister M, Najjar R, Danh J, Knapp D, Wanders D, Feresin R. Berry consumption mitigates the hypertensive effects of a high-fat, high-sucrose diet via attenuation of renal and aortic AT1R expression resulting in improved endothelium-derived NO bioavailability. J Nutr Biochem. 2023;112:109225 pubmed publisher
Hwang S, Kim S, Yoo K, Chung M, Lee J, Son K. Exogenous 8-hydroxydeoxyguanosine attenuates doxorubicin-induced cardiotoxicity by decreasing pyroptosis in H9c2 cardiomyocytes. BMC Mol Cell Biol. 2022;23:55 pubmed publisher
Najjar R, Mu S, Feresin R. Blueberry Polyphenols Increase Nitric Oxide and Attenuate Angiotensin II-Induced Oxidative Stress and Inflammatory Signaling in Human Aortic Endothelial Cells. Antioxidants (Basel). 2022;11: pubmed publisher
Tarafdar A, Wolska N, Krisp C, Schluter H, Pula G. The amyloid peptide β disrupts intercellular junctions and increases endothelial permeability in a NADPH oxidase 1-dependent manner. Redox Biol. 2022;52:102287 pubmed publisher
Oh S, Yang J, Park C, Son K, Byun K. Dieckol Reduces Muscle Atrophy by Modulating Angiotensin Type II Type 1 Receptor and NADPH Oxidase in Spontaneously Hypertensive Rats. Antioxidants (Basel). 2021;10: pubmed publisher
Gaspar R, Sage T, Little G, Kriek N, Pula G, Gibbins J. Protein Disulphide Isomerase and NADPH Oxidase 1 Cooperate to Control Platelet Function and Are Associated with Cardiometabolic Disease Risk Factors. Antioxidants (Basel). 2021;10: pubmed publisher
Gaspar R, Ferreira P, Mitchell J, Pula G, Gibbins J. Platelet-derived extracellular vesicles express NADPH oxidase-1 (Nox-1), generate superoxide and modulate platelet function. Free Radic Biol Med. 2021;165:395-400 pubmed publisher
Attri P, Park J, De Backer J, Kim M, Yun J, Heo Y, et al. Structural modification of NADPH oxidase activator (Noxa 1) by oxidative stress: An experimental and computational study. Int J Biol Macromol. 2020;163:2405-2414 pubmed publisher
Raut P, Park P. Globular adiponectin antagonizes leptin-induced growth of cancer cells by modulating inflammasomes activation: Critical role of HO-1 signaling. Biochem Pharmacol. 2020;180:114186 pubmed publisher
Wang X, Zhang S, Ding Y, Tong H, Xu X, Wei G, et al. p47phox deficiency impairs platelet function and protects mice against arterial and venous thrombosis. Redox Biol. 2020;34:101569 pubmed publisher
Wang C, Zhu L, Yuan W, Sun L, Xia Z, Zhang Z, et al. Diabetes aggravates myocardial ischaemia reperfusion injury via activating Nox2-related programmed cell death in an AMPK-dependent manner. J Cell Mol Med. 2020;24:6670-6679 pubmed publisher
Cao L, Li X, XU R, Yao K, Yang W, Zhu H, et al. DUOX2, a common modulator in preventive effects of monoamine-based antidepressants on water immersion restraint stress- and indomethacin- induced gastric mucosal damage. Eur J Pharmacol. 2020;876:173058 pubmed publisher
Quinones J, Thapar U, Wilson S, Ramsden D, Demple B. Oxidative DNA-protein crosslinks formed in mammalian cells by abasic site lyases involved in DNA repair. DNA Repair (Amst). 2020;87:102773 pubmed publisher
Shin S, Kim K, Kim S, Kwon O, Choi C, Jeong S, et al. Exogenous 8-hydroxydeoxyguanosine ameliorates liver fibrosis through the inhibition of Rac1-NADPH oxidase signaling. J Gastroenterol Hepatol. 2020;35:1078-1087 pubmed publisher
Wang T, Su H, Lou W, Gu J, He X, Chen L, et al. Experimental supporting data on evaluation of skeletal muscle perfusion in canine hind limb ischemia model using color-coded digital subtraction angiography. Data Brief. 2019;25:103737 pubmed publisher
Diebold B, Wilder S, De Deken X, Meitzler J, Doroshow J, McCoy J, et al. Guidelines for the Detection of NADPH Oxidases by Immunoblot and RT-qPCR. Methods Mol Biol. 2019;1982:191-229 pubmed publisher
Zhang Q, Chao T, Patil V, Qin Y, Tiwari S, Chiou J, et al. The long noncoding RNA ROCKI regulates inflammatory gene expression. EMBO J. 2019;38: pubmed publisher
Pascut D, Sukowati C, Antoniali G, Mangiapane G, Burra S, Mascaretti L, et al. Serum AP-endonuclease 1 (sAPE1) as novel biomarker for hepatocellular carcinoma. Oncotarget. 2019;10:383-394 pubmed publisher
Vara D, Cifuentes Pagano E, Pagano P, Pula G. A novel combinatorial technique for simultaneous quantification of oxygen radicals and aggregation reveals unexpected redox patterns in the activation of platelets by different physiopathological stimuli. Haematologica. 2019;: pubmed publisher
Raut P, Kim S, Choi D, Jeong G, Park P. Growth of breast cancer cells by leptin is mediated via activation of the inflammasome: Critical roles of estrogen receptor signaling and reactive oxygen species production. Biochem Pharmacol. 2019;161:73-88 pubmed publisher
Stuart J, Fonseca J, Moradi F, Cunningham C, Seliman B, Worsfold C, et al. How Supraphysiological Oxygen Levels in Standard Cell Culture Affect Oxygen-Consuming Reactions. Oxid Med Cell Longev. 2018;2018:8238459 pubmed publisher
Kumar S, Talluri S, Pal J, Yuan X, Lu R, Nanjappa P, et al. Role of apurinic/apyrimidinic nucleases in the regulation of homologous recombination in myeloma: mechanisms and translational significance. Blood Cancer J. 2018;8:92 pubmed publisher
Logsdon D, Shah F, Carta F, Supuran C, Kamocka M, Jacobsen M, et al. Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival. Sci Rep. 2018;8:13759 pubmed publisher
Fehrenbacher J, Guo C, Kelley M, Vasko M. DNA damage mediates changes in neuronal sensitivity induced by the inflammatory mediators, MCP-1 and LPS, and can be reversed by enhancing the DNA repair function of APE1. Neuroscience. 2017;366:23-35 pubmed publisher
Shah F, Logsdon D, Messmann R, Fehrenbacher J, Fishel M, Kelley M. Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic. NPJ Precis Oncol. 2017;1: pubmed publisher
Shin S, Cho J, Kim E, Kim E, Park D, Kwon K, et al. Anti-inflammatory and anti-apoptotic effects of rosuvastatin by regulation of oxidative stress in a dextran sulfate sodium-induced colitis model. World J Gastroenterol. 2017;23:4559-4568 pubmed publisher
Kangawa Y, Yoshida T, Maruyama K, Okamoto M, Kihara T, Nakamura M, et al. Cilostazol and enzymatically modified isoquercitrin attenuate experimental colitis and colon cancer in mice by inhibiting cell proliferation and inflammation. Food Chem Toxicol. 2017;100:103-114 pubmed publisher
Wyssenbach A, Quintela T, Llavero F, Zugaza J, Matute C, Alberdi E. Amyloid β-induced astrogliosis is mediated by β1-integrin via NADPH oxidase 2 in Alzheimer's disease. Aging Cell. 2016;15:1140-1152 pubmed publisher
Sandomenico A, Focà A, Sanguigno L, Caporale A, Focà G, Pignalosa A, et al. Monoclonal antibodies against pools of mono- and polyacetylated peptides selectively recognize acetylated lysines within the context of the original antigen. MAbs. 2016;8:1575-1589 pubmed
Logsdon D, Grimard M, Luo M, Shahda S, Jiang Y, Tong Y, et al. Regulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models. Mol Cancer Ther. 2016;15:2722-2732 pubmed
Nassour H, Wang Z, Saad A, Papaluca A, Brosseau N, Affar E, et al. Peroxiredoxin 1 interacts with and blocks the redox factor APE1 from activating interleukin-8 expression. Sci Rep. 2016;6:29389 pubmed publisher
Pekarčíková L, Knopfova L, Benes P, Smarda J. c-Myb regulates NOX1/p38 to control survival of colorectal carcinoma cells. Cell Signal. 2016;28:924-36 pubmed publisher
Kwon J, Wang A, Burke D, Boudreau H, Lekstrom K, Korzeniowska A, et al. Peroxiredoxin 6 (Prdx6) supports NADPH oxidase1 (Nox1)-based superoxide generation and cell migration. Free Radic Biol Med. 2016;96:99-115 pubmed publisher
Poletto M, Legrand A, Fletcher S, Dianov G. p53 coordinates base excision repair to prevent genomic instability. Nucleic Acids Res. 2016;44:3165-75 pubmed publisher
Sanchez J, Reddick T, Perez M, Centonze V, Mitra S, Izumi T, et al. Increased human AP endonuclease 1 level confers protection against the paternal age effect in mice. Mutat Res. 2015;779:124-33 pubmed publisher
Quiñones J, Thapar U, Yu K, Fang Q, Sobol R, Demple B. Enzyme mechanism-based, oxidative DNA-protein cross-links formed with DNA polymerase β in vivo. Proc Natl Acad Sci U S A. 2015;112:8602-7 pubmed publisher
Iglesias Ara A, Zenarruzabeitia O, Buelta L, Merino J, Zubiaga A. E2F1 and E2F2 prevent replicative stress and subsequent p53-dependent organ involution. Cell Death Differ. 2015;22:1577-89 pubmed publisher
Zhao Q, Viswanadhapalli S, Williams P, Shi Q, Tan C, Yi X, et al. NADPH oxidase 4 induces cardiac fibrosis and hypertrophy through activating Akt/mTOR and NFκB signaling pathways. Circulation. 2015;131:643-55 pubmed publisher
product information
master code :
NBP1-31546
SKU :
NBP1-31546
product name :
NOX1 Antibody - BSA Free
unit size :
100 ul
description :
The NOX1 Antibody - Azide Free from Novus is a rabbit polyclonal antibody to NOX1. This antibody reacts with human,mouse,rat. The NOX1 Antibody - Azide Free has been validated for the following applications: Flow Cytometry,Western Blot,IHC-P WB,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry.
target :
NOX1
category :
Primary Antibodies
buffer :
PBS (pH 7), 20% Glycerol
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Recombinant protein encompassing a sequence within the center region of human NOX1. The exact sequence is proprietary.
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Rat
theoretical molecular weight :
65 kDa
gene symbol :
NOX1
accessionNumbers :
Q9Y5S8
applications :
Flow Cytometry,Western Blot,IHC-P WB,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry
USD :
449 USD
alt names :
EC 1.6.3, GP91-2, Mitogenic oxidase 1, MOX-1, MOX1NADH/NADPH mitogenic oxidase subunit P65-MOX, NADPH oxidase 1, NADPH oxidase homolog-1, NOH1mitogenic oxidase (pyridine nucleotide-dependent superoxide-generating), NOH-1NADPH oxidase 1 variant NOH-1L, NOX-1
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.