product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Topoisomerase I Antibody
catalog :
NBP1-30482
quantity :
100 ul
price :
459 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
citations: 2
Reference
Chatzinikolaou G, Stratigi K, Siametis A, Goulielmaki E, Akalestou Clocher A, Tsamardinos I, et al. XPF interacts with TOP2B for R-loop processing and DNA looping on actively transcribed genes. Sci Adv. 2023;9:eadi2095 pubmed publisher
Chatzidoukaki O, Stratigi K, Goulielmaki E, Niotis G, Akalestou Clocher A, Gkirtzimanaki K, et al. R-loops trigger the release of cytoplasmic ssDNAs leading to chronic inflammation upon DNA damage. Sci Adv. 2021;7:eabj5769 pubmed publisher
image
image 1 :
Novus Biologicals NBP1-30482 image 1
Western Blot: Topoisomerase I Antibody [NBP1-30482] - Detection of Human TOP1 by Western Blot. Samples: Whole cell lysate (50, 15, 5 ug) from HeLa and (50 ug) from 293T and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-TOP1 antibody NBP1-30482 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
product information
brand :
Novus Biologicals, a Bio-Techne brand
catalog number base :
NBP1-30482
SKU :
NBP1-30482
product name :
Topoisomerase I Antibody
description :
The Topoisomerase I Antibody from Novus Biologicals is a rabbit polyclonal antibody to Topoisomerase I. This antibody reacts with human,mouse. The Topoisomerase I Antibody has been validated for the following applications: Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence.
target :
Topoisomerase I
unit size :
100 ul
category :
Primary Antibodies
buffer :
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
The immunogen for this product maps to a region between residue 715 and 765 of human DNA topoisomerase I using the numbering given in entry NP_003277.1 (GeneID 7150).
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse
storage :
Store at 4C. Do not freeze.
theoretical molecular weight :
91 kDa
gene symbol :
TOP1
Antibody validation :
Biological Validation
accessionNumbers :
P11387
applications :
Immunoprecipitation,Western Blot,Immunocytochemistry/ Immunofluorescence
USD :
449
USD 2025 :
459 USD
alt names :
DNA topoisomerase 1, DNA topoisomerase I, EC 5.99.1.2, TOPI, topoisomerase (DNA) I, type I DNA topoisomerase
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.