EGLN3/PHD3 Antibody (EG188e/d5) | Novus Biologicals NBP1-30440 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

EGLN3/PHD3 Antibody (EG188e/d5)

catalog :

NBP1-30440

quantity :

0.2 ml (also 0.05 ml)

price :

329 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

EG188e/d5

reactivity :

human, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
western blot; rat	Fujita N, Gogate S, Chiba K, Toyama Y, Shapiro I, Risbud M. Prolyl hydroxylase 3 (PHD3) modulates catabolic effects of tumor necrosis factor-? (TNF-?) on cells of the nucleus pulposus through co-activation of nuclear factor ?B (NF-?B)/p65 signaling. J Biol Chem. 2012;287:39942-53 pubmed publisher
immunohistochemistry - paraffin section; human	Soilleux E, Turley H, Tian Y, Pugh C, Gatter K, Harris A. Use of novel monoclonal antibodies to determine the expression and distribution of the hypoxia regulatory factors PHD-1, PHD-2, PHD-3 and FIH in normal and neoplastic human tissues. Histopathology. 2005;47:602-10 pubmed
western blot; human	Appelhoff R, Tian Y, Raval R, Turley H, Harris A, Pugh C, et al. Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor. J Biol Chem. 2004;279:38458-65 pubmed
	Pavlakis D, Kampantais S, Gkagkalidis K, Gourvas V, Memmos D, Tsionga A, et al. Hypoxia-Inducible Factor 2a Expression Is Positively Correlated With Gleason Score in Prostate Cancer. Technol Cancer Res Treat. 2021;20:1533033821990010 pubmed publisher
	Capitanio D, Moriggi M, Torretta E, Barbacini P, De Palma S, Vigano A, et al. Comparative proteomic analyses of Duchenne muscular dystrophy and Becker muscular dystrophy muscles: changes contributing to preserve muscle function in Becker muscular dystrophy patients. J Cachexia Sarcopenia Muscle. 2020;11:547-563 pubmed publisher
	Bur H, Haapasaari K, Turpeenniemi Hujanen T, Kuittinen O, Auvinen P, Marin K, et al. Strong Prolyl Hydroxylase Domain 1 Expression Predicts Poor Outcome in Radiotherapy-treated Patients with Classical Hodgkin's Lymphoma. Anticancer Res. 2018;38:329-336 pubmed
	Zhang G, Yu F, Li Y, Wei Q, Song S, Zhou F, et al. Prolyl 4-Hydroxylase Domain Protein 3 Overexpression Improved Obstructive Sleep Apnea-Induced Cardiac Perivascular Fibrosis Partially by Suppressing Endothelial-to-Mesenchymal Transition. J Am Heart Assoc. 2017;6: pubmed publisher
	Kowalik M, Guzzo G, Morandi A, Perra A, Menegon S, Masgras I, et al. Metabolic reprogramming identifies the most aggressive lesions at early phases of hepatic carcinogenesis. Oncotarget. 2016;7:32375-93 pubmed publisher
	Mysore V, Szablowski J, Dervan P, FROST P. A DNA-binding Molecule Targeting the Adaptive Hypoxic Response in Multiple Myeloma Has Potent Antitumor Activity. Mol Cancer Res. 2016;14:253-66 pubmed publisher
	Stolze I, Tian Y, Appelhoff R, Turley H, Wykoff C, Gleadle J, et al. Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected]. J Biol Chem. 2004;279:42719-25 pubmed

product information

brand :

Novus

master code :

NBP1-30440

SKU :

NBP1-30440

product name :

EGLN3/PHD3 Antibody (EG188e/d5)

description :

The EGLN3/PHD3 Antibody (EG188e/d5) from NBP1-30440 is a nbp1-30440 antibody to . This antibody reacts with apoptosis, cancer, hypoxia. The EGLN3/PHD3 Antibody (EG188e/d5) has been validated for the following applications: Q9H6Z9.

target :

EGLN3/PHD3

category :

Primary Antibodies

unit sizes :

0.2 ml (also 0.05 ml)

buffer :

PBS

clonality :

Monoclonal

clone :

EG188e/d5

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

Partial recombinant human PHD3/HIF Prolyl Hydroxylase 3 (UniProt# Q9H6Z9)

isotype :

IgG1

purity :

Protein G purified

species :

Human, Rat

theoretical molecular weight :

27 kDa

gene symbol :

EGLN3

accessionNumbers :

Q9H6Z9

applications :

Western Blot, Simple Western, Immunohistochemistry, Immunohistochemistry-Paraffin

USD :

329 USD

alt names :

EC 1.14.11, EC 1.14.11.-, EGL nine (C.elegans) homolog 3, egl nine homolog 3, egl nine homolog 3 (C. elegans), egl nine-like protein 3 isoform, FLJ21620, HIF prolyl hydroxylase 3, HIF-PH3, HIFPH3 MGC125998, HIF-prolyl hydroxylase 3, HPH-1, HPH-3, Hypoxia-inducible factor prolyl hydroxylase 3, MGC125999, pdh3, PHD3, Prolyl hydroxylase domain-containing protein 3

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage