EGLN1/PHD2 Antibody (366G/76/3) | Novus Biologicals NBP1-30328 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

EGLN1/PHD2 Antibody (366G/76/3)

catalog :

NBP1-30328

quantity :

0.1 ml (also 0.025 ml)

price :

329 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

366G/76/3

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human	Jubb A, Turley H, Moeller H, Steers G, Han C, Li J, et al. Expression of delta-like ligand 4 (Dll4) and markers of hypoxia in colon cancer. Br J Cancer. 2009;101:1749-57 pubmed publisher
immunohistochemistry - paraffin section; human	Soilleux E, Turley H, Tian Y, Pugh C, Gatter K, Harris A. Use of novel monoclonal antibodies to determine the expression and distribution of the hypoxia regulatory factors PHD-1, PHD-2, PHD-3 and FIH in normal and neoplastic human tissues. Histopathology. 2005;47:602-10 pubmed
western blot; human	Stolze I, Tian Y, Appelhoff R, Turley H, Wykoff C, Gleadle J, et al. Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected]. J Biol Chem. 2004;279:42719-25 pubmed
western blot; human	Appelhoff R, Tian Y, Raval R, Turley H, Harris A, Pugh C, et al. Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor. J Biol Chem. 2004;279:38458-65 pubmed
	Pavlakis D, Kampantais S, Gkagkalidis K, Gourvas V, Memmos D, Tsionga A, et al. Hypoxia-Inducible Factor 2a Expression Is Positively Correlated With Gleason Score in Prostate Cancer. Technol Cancer Res Treat. 2021;20:1533033821990010 pubmed publisher
	Chowdhury D, Alrefai H, Landero Figueroa J, Candor K, Porollo A, Fecher R, et al. Metallothionein 3 Controls the Phenotype and Metabolic Programming of Alternatively Activated Macrophages. Cell Rep. 2019;27:3873-3886.e7 pubmed publisher
	Rane A, Rajagopalan S, Ahuja M, Thomas B, Chinta S, Andersen J. Hsp90 Co-chaperone p23 contributes to dopaminergic mitochondrial stress via stabilization of PHD2: Implications for Parkinson's disease. Neurotoxicology. 2018;65:166-173 pubmed publisher
	Capitanio D, Fania C, Torretta E, Vigano A, Moriggi M, Bravatà V, et al. TCA cycle rewiring fosters metabolic adaptation to oxygen restriction in skeletal muscle from rodents and humans. Sci Rep. 2017;7:9723 pubmed publisher
	Casciello F, Al Ejeh F, Kelly G, Brennan D, Ngiow S, Young A, et al. G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis. Proc Natl Acad Sci U S A. 2017;114:7077-7082 pubmed publisher

product information

brand :

Novus

master code :

NBP1-30328

SKU :

NBP1-30328

product name :

EGLN1/PHD2 Antibody (366G/76/3)

description :

The EGLN1/PHD2 Antibody (366G/76/3) from NBP1-30328 is a nbp1-30328 antibody to . This antibody reacts with angiogenesis, cancer, chromatin research, hypoxia, immunology, lipid and metabolism. The EGLN1/PHD2 Antibody (366G/76/3) has been validated for the following applications: Q9GZT9.

target :

EGLN1/PHD2

category :

Primary Antibodies

unit sizes :

0.1 ml (also 0.025 ml)

buffer :

Tris-Glycine, 0.15 M NaCl

clonality :

Monoclonal

clone :

366G/76/3

concentration :

1 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

This EGLN1/PHD2 antibody was developed against a peptide within residues 1-50 of human PHD2/HIF Prolyl Hydroxylase 2. [Swiss-Prot# Q9GZT9]

isotype :

IgG1

purity :

Protein G purified

species :

Human, Mouse, Rat

theoretical molecular weight :

46 kDa

gene symbol :

EGLN1

accessionNumbers :

Q9GZT9

applications :

Western Blot, Simple Western, Immunohistochemistry, Immunohistochemistry-Paraffin

USD :

329 USD

alt names :

C1orf12, EC 1.14.11.29, EC:1.14.11.291, ECYT3, egl nine homolog 1, egl nine-like protein 1, EGLN1, HALAH, HIF prolyl hydroxylase 2, HIFPH2, HIF-PH2, HIF-prolyl hydroxylase 2, HPH2, HPH-2, Hypoxia-inducible factor prolyl hydroxylase 2, PHD2, PNAS-118, PNAS-137, Prolyl hydroxylase domain-containing protein 2, SM20, SM-20, zinc finger MYND domain-containing protein 6, ZMYND6

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage