Nephrin Antibody (Y17-R) | Novus Biologicals NBP1-30130-0.05ml product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Nephrin Antibody (Y17-R)

catalog :

NBP1-30130-0.05ml

quantity :

0.05 ml

price :

429 USD

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

Y17-R

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 7

Reference
Pace J, Bronstein R, Guo Y, Yang Y, Estrada C, Gujarati N, et al. Podocyte-specific KLF4 is required to maintain parietal epithelial cell quiescence in the kidney. Sci Adv. 2021;7:eabg6600 pubmed publisher
Melica M, La Regina G, Parri M, Peired A, Romagnani P, Lasagni L. Substrate Stiffness Modulates Renal Progenitor Cell Properties via a ROCK-Mediated Mechanotransduction Mechanism. Cells. 2019;8: pubmed publisher
Wang X, Gao Y, Tian N, Zou D, Shi Y, Zhang N. Astragaloside IV improves renal function and fibrosis via inhibition of miR-21-induced podocyte dedifferentiation and mesangial cell activation in diabetic mice. Drug Des Devel Ther. 2018;12:2431-2442 pubmed publisher
Estrada C, Paladugu P, Guo Y, Pace J, Revelo M, Salant D, et al. Krüppel-like factor 4 is a negative regulator of STAT3-induced glomerular epithelial cell proliferation. JCI Insight. 2018;3: pubmed publisher
Hu M, Azeloglu E, Ron A, Tran Ba K, Calizo R, Tavassoly I, et al. A biomimetic gelatin-based platform elicits a pro-differentiation effect on podocytes through mechanotransduction. Sci Rep. 2017;7:43934 pubmed publisher
Mallipattu S, Guo Y, Revelo M, Roa Peña L, Miller T, Ling J, et al. Krüppel-Like Factor 15 Mediates Glucocorticoid-Induced Restoration of Podocyte Differentiation Markers. J Am Soc Nephrol. 2017;28:166-184 pubmed publisher
Finne K, Vethe H, Skogstrand T, Leh S, Dahl T, Tenstad O, et al. Proteomic analysis of formalin-fixed paraffin-embedded glomeruli suggests depletion of glomerular filtration barrier proteins in two-kidney, one-clip hypertensive rats. Nephrol Dial Transplant. 2014;29:2217-27 pubmed publisher

image

image 1 :

Western Blot: Nephrin Antibody (Y17-R) [NBP1-30130] - Stiffness-mediated differentiation phenotype induces upregulation of podocyte-specific functional proteins. Representative image of Western blot for Nephrin antibody critical for physiological function of podocytes. Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/srep43934) licensed under a CC-BY licence.

product information

brand :

Novus

master code :

NBP1-30130

SKU :

NBP1-30130-0.05ml

product name :

Nephrin Antibody (Y17-R)

description :

The Nephrin Antibody (Y17-R) from Novus is a rabbit monoclonal antibody to Nephrin. This antibody reacts with human, mouse, rat. The Nephrin Antibody (Y17-R) has been validated for the following applications: Western Blot, ELISA, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin.

target :

Nephrin

category :

Primary Antibodies

sizes available :

0.05 ml

buffer :

20mM Tris/HCl (pH 8.0) and 10 mg/ml BSA

clonality :

Monoclonal

clone :

Y17-R

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Peptide derived from the center of the fifth Ig-like domain of human Nephrin. Antibody recognizes the epitope located between Cys465 - Cys528.

isotype :

IgG

purity :

Immunogen affinity purified

species :

Human, Mouse, Rat

gene symbol :

NPHS1

images :

https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Nephrin-Antibody-(Y17-R)-Western-Blot-NBP1-30130-img0003.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Nephrin-Antibody-(Y17-R)-Western-Blot-NBP1-30130-img0003.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Nephrin-Antibody-(Y17-R)-Western-Blot-NBP1-30130-img0003.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Nephrin-Antibody-(Y17-R)-Immunocytochemistry-Immunofluorescence-NBP1-30130-img0002.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Nephrin-Antibody-(Y17-R)-Immunocytochemistry-Immunofluorescence-NBP1-30130-img0002.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Nephrin-Antibody-(Y17-R)-Immunocytochemistry-Immunofluorescence-NBP1-30130-img0002.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Nephrin-Antibody-(I)-Western-Blot-NBP1-30130-img0001.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Nephrin-Antibody-(I)-Western-Blot-NBP1-30130-img0001.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Nephrin-Antibody-(I)-Western-Blot-NBP1-30130-img0001.jpg

accessionNumbers :

O60500, Q9QZS7, Q9R044

applications :

Western Blot, ELISA, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin

extended description :

Recombinant Monoclonal Antibody.

USD :

429 USD

product details :

Recombinant Monoclonal Antibody.

alt names :

nephrin, nephrosis 1, congenital, Finnish type (nephrin), NPHNCNF, Renal glomerulus-specific cell adhesion receptor

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage