Prox1 Antibody (5G10) - BSA Free | Novus Biologicals NBP1-30045 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Prox1 Antibody (5G10) - BSA Free

catalog :

NBP1-30045

quantity :

0.1 ml (also 0.025 ml)

price :

439 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5G10

reactivity :

human, mouse, rat, chicken

application :

ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 27

Reference
Iskusnykh I, Fattakhov N, Li Y, Bihannic L, Kirchner M, Steshina E, et al. Lmx1a is a master regulator of the cortical hem. elife. 2023;12: pubmed publisher
R xfc tsche D, Nanni M, R xfc disser S, Biedermann T, Zenobi Wong M. Enzymatically Crosslinked Collagen as a Versatile Matrix for In Vitro and In Vivo Co-Engineering of Blood and Lymphatic Vasculature. Adv Mater. 2023;35:e2209476 pubmed publisher
Wang T, Wang Z, De Fabritus L, Tao J, Saied E, Lee H, et al. 1-deoxysphingolipids bind to COUP-TF to modulate lymphatic and cardiac cell development. Dev Cell. 2021;56:3128-3145.e15 pubmed publisher
Taira Y, Ikuta Y, Inamori S, Nunome M, Nakano M, Suzuki T, et al. The formation of multiple pituitary pouches from the oral ectoderm causes ectopic lens development in hedgehog signaling-defective avian embryos. Dev Dyn. 2020;: pubmed publisher
Wu S, Xu Q, Sheng W, Su L, Zhu L. A novel role for Livin in the response to ultraviolet B radiation and pterygium development. Int J Mol Med. 2020;45:1103-1111 pubmed publisher
Gong M, Lugo Cintron K, White B, Kerr S, Harari P, Beebe D. Human organotypic lymphatic vessel model elucidates microenvironment-dependent signaling and barrier function. Biomaterials. 2019;214:119225 pubmed publisher
Tchoghandjian A, Soubéran A, Tabouret E, Colin C, Denicolaï E, Jiguet Jiglaire C, et al. Inhibitor of apoptosis protein expression in glioblastomas and their in vitro and in vivo targeting by SMAC mimetic GDC-0152. Cell Death Dis. 2016;7:e2325 pubmed publisher
Shiloach T, Berens C, Danke C, Waiskopf O, Perlman R, Ben Yehuda D. tLivin displays flexibility by promoting alternative cell death mechanisms. PLoS ONE. 2014;9:e101075 pubmed publisher
Sweat R, Sloas D, Murfee W. VEGF-C induces lymphangiogenesis and angiogenesis in the rat mesentery culture model. Microcirculation. 2014;21:532-40 pubmed publisher
Liu X, Wang A, Gao H, Yuan Z, Jiao Y. Expression and role of the inhibitor of apoptosis protein livin in chemotherapy sensitivity of ovarian carcinoma. Int J Oncol. 2012;41:1021-8 pubmed publisher
Lazar I, Perlman R, Lotem M, Peretz T, Ben Yehuda D, Kadouri L. The clinical effect of the inhibitor of apopotosis protein livin in melanoma. Oncology. 2012;82:197-204 pubmed publisher
Slagsvold J, Pettersen C, Størvold G, Follestad T, Krokan H, Schønberg S. DHA alters expression of target proteins of cancer therapy in chemotherapy resistant SW620 colon cancer cells. Nutr Cancer. 2010;62:611-21 pubmed publisher
Lazar I, Yaacov B, Shiloach T, Eliahoo E, Kadouri L, Lotem M, et al. The oncolytic activity of Newcastle disease virus NDV-HUJ on chemoresistant primary melanoma cells is dependent on the proapoptotic activity of the inhibitor of apoptosis protein Livin. J Virol. 2010;84:639-46 pubmed publisher
Fakler M, Loeder S, Vogler M, Schneider K, Jeremias I, Debatin K, et al. Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance. Blood. 2009;113:1710-22 pubmed publisher
Wang H, Tan S, Wang X, Liu D, Yu C, Bai Z, et al. Silencing livin gene by siRNA leads to apoptosis induction, cell cycle arrest, and proliferation inhibition in malignant melanoma LiBr cells. Acta Pharmacol Sin. 2007;28:1968-74 pubmed
Crnkovic Mertens I, Wagener N, Semzow J, Gröne E, Haferkamp A, Hohenfellner M, et al. Targeted inhibition of Livin resensitizes renal cancer cells towards apoptosis. Cell Mol Life Sci. 2007;64:1137-44 pubmed
Kleinberg L, Lie A, Flørenes V, Nesland J, Davidson B. Expression of inhibitor-of-apoptosis protein family members in malignant mesothelioma. Hum Pathol. 2007;38:986-94 pubmed
Nachmias B, Lazar I, Elmalech M, Abed El Rahaman I, Asshab Y, Mandelboim O, et al. Subcellular localization determines the delicate balance between the anti- and pro-apoptotic activity of Livin. Apoptosis. 2007;12:1129-42 pubmed
Gordon G, Mani M, Mukhopadhyay L, Dong L, Yeap B, Sugarbaker D, et al. Inhibitor of apoptosis proteins are regulated by tumour necrosis factor-alpha in malignant pleural mesothelioma. J Pathol. 2007;211:439-46 pubmed
Gordon G, Mani M, Mukhopadhyay L, Dong L, Edenfield H, Glickman J, et al. Expression patterns of inhibitor of apoptosis proteins in malignant pleural mesothelioma. J Pathol. 2007;211:447-54 pubmed
Choi J, Hwang Y, Sung K, Lee S, Yoo K, Jung H, et al. Expression of Livin, an antiapoptotic protein, is an independent favorable prognostic factor in childhood acute lymphoblastic leukemia. Blood. 2007;109:471-7 pubmed
Ma L, Huang Y, Song Z, Feng S, Tian X, Du W, et al. Livin promotes Smac/DIABLO degradation by ubiquitin-proteasome pathway. Cell Death Differ. 2006;13:2079-88 pubmed
Crnkovic Mertens I, Semzow J, Hoppe Seyler F, Butz K. Isoform-specific silencing of the Livin gene by RNA interference defines Livin beta as key mediator of apoptosis inhibition in HeLa cells. J Mol Med (Berl). 2006;84:232-40 pubmed
Qiuping Z, Jei X, Youxin J, Wei J, Chun L, Jin W, et al. CC chemokine ligand 25 enhances resistance to apoptosis in CD4+ T cells from patients with T-cell lineage acute and chronic lymphocytic leukemia by means of livin activation. Cancer Res. 2004;64:7579-87 pubmed
Yang Q, Du C. Smac/DIABLO selectively reduces the levels of c-IAP1 and c-IAP2 but not that of XIAP and livin in HeLa cells. J Biol Chem. 2004;279:16963-70 pubmed
Crnkovic Mertens I, Hoppe Seyler F, Butz K. Induction of apoptosis in tumor cells by siRNA-mediated silencing of the livin/ML-IAP/KIAP gene. Oncogene. 2003;22:8330-6 pubmed
Nachmias B, Ashhab Y, Bucholtz V, Drize O, Kadouri L, Lotem M, et al. Caspase-mediated cleavage converts Livin from an antiapoptotic to a proapoptotic factor: implications for drug-resistant melanoma. Cancer Res. 2003;63:6340-9 pubmed

product information

master code :

NBP1-30045

SKU :

NBP1-30045

product name :

Prox1 Antibody (5G10) - BSA Free

unit size :

0.1 ml (also 0.025 ml)

description :

The Prox1 Antibody (5G10) - BSA Free from Novus is a mouse monoclonal antibody to Prox1. This antibody reacts with chicken,human,mouse,rat. The Prox1 Antibody (5G10) - BSA Free has been validated for the following applications: Flow Cytometry,Immunohistochemistry Whole-Mount,ELISA,Immunohistochemistry,Immunohistochemistry-Paraffin,CyTOF-ready,Immunocytochemistry/ Immunofluorescence.

target :

Prox1

category :

Primary Antibodies

buffer :

PBS

clonality :

Monoclonal

clone :

5G10

concentration :

1.0 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

The highly conserved Homeo and Prospero domain of human Prox1. [UniProt# Q92786]

isotype :

IgG1

purity :

Protein G purified

species :

Chicken,Human,Mouse,Rat

gene symbol :

PROX1

accessionNumbers :

Q92786, Q92786, P48437

applications :

Flow Cytometry,Immunohistochemistry Whole-Mount,ELISA,Immunohistochemistry,Immunohistochemistry-Paraffin,CyTOF-ready,Immunocytochemistry/ Immunofluorescence

USD :

439 USD

alt names :

Homeobox prospero-like protein PROX1, prospero homeobox 1, prospero homeobox protein 1, prospero-related homeobox 1, PROX-1

storage :

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage