ABCA4 Antibody (3F4) - Azide Free | Novus Biologicals NBP1-30032 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

ABCA4 Antibody (3F4) - Azide Free

catalog :

NBP1-30032

quantity :

0.1 ml

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3F4

reactivity :

human, mouse, dogs, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section, immunohistochemistry knockout validation

more info or order :

Novus Biologicals product webpage

citations: 20

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry knockout validation; dogs; 1:1000; loading ...; fig 4c	Mäkeläinen S, Gòdia M, Hellsand M, Viluma A, Hahn D, Makdoumi K, et al. An ABCA4 loss-of-function mutation causes a canine form of Stargardt disease. PLoS Genet. 2019;15:e1007873 pubmed publisher
	Xiang H, Zhang B, Wang Y, Xu N, Zhang F, Luo R, et al. Region-resolved multi-omics of the mouse eye. Cell Rep. 2023;42:112121 pubmed publisher
	Taveau N, Cubizolle A, Guillou L, Pinquier N, Moine E, Cia D, et al. Preclinical pharmacology of a lipophenol in a mouse model of light-induced retinopathy. Exp Mol Med. 2020;52:1090-1101 pubmed publisher
	Wang L, He L, Zeng H, Fu W, Wang J, Tan Y, et al. Low-dose microcystin-LR antagonizes aflatoxin B1 induced hepatocarcinogenesis through decreasing cytochrome P450 1A2 expression and aflatoxin B1-DNA adduct generation. Chemosphere. 2020;248:126036 pubmed publisher
	Kim J, Park S, Do K, Kim D, Moon Y. Interference with mutagenic aflatoxin B1-induced checkpoints through antagonistic action of ochratoxin A in intestinal cancer cells: a molecular explanation on potential risk of crosstalk between carcinogens. Oncotarget. 2016;7:39627-39639 pubmed publisher
	Qureshi H, Hamid S, Ali S, Anwar J, Siddiqui A, Khan N. Cytotoxic effects of aflatoxin B1 on human brain microvascular endothelial cells of the blood-brain barrier. Med Mycol. 2015;53:409-16 pubmed publisher
	Liu Y, Long X, Xi Z, Ma Y, Huang X, Yao J, et al. MicroRNA-24 modulates aflatoxin B1-related hepatocellular carcinoma prognosis and tumorigenesis. Biomed Res Int. 2014;2014:482926 pubmed publisher
	Qi L, Bai T, Chen Z, Wu F, Chen Y, De Xiang B, et al. The p53 mutation spectrum in hepatocellular carcinoma from Guangxi, China : role of chronic hepatitis B virus infection and aflatoxin B1 exposure. Liver Int. 2015;35:999-1009 pubmed publisher
	Qi L, Li L, Chen Y, Chen Z, Bai T, Xiang B, et al. Genome-wide and differential proteomic analysis of hepatitis B virus and aflatoxin B1 related hepatocellular carcinoma in Guangxi, China. PLoS ONE. 2013;8:e83465 pubmed publisher
	Huang X, Yao J, Huang H, Wang C, Ma Y, Xia Q, et al. MicroRNA-429 Modulates Hepatocellular Carcinoma Prognosis and Tumorigenesis. Gastroenterol Res Pract. 2013;2013:804128 pubmed publisher
	Zhang Z, Lu H, Huan F, Meghan C, Yang X, Wang Y, et al. Cytochrome P450 2A13 mediates the neoplastic transformation of human bronchial epithelial cells at a low concentration of aflatoxin B1. Int J Cancer. 2014;134:1539-48 pubmed publisher
	Yang X, Zhang Z, Wang X, Wang Y, Zhang X, Lu H, et al. Cytochrome P450 2A13 enhances the sensitivity of human bronchial epithelial cells to aflatoxin B1-induced DNA damage. Toxicol Appl Pharmacol. 2013;270:114-21 pubmed publisher
	Lu J, Yang W, Lin Y, Jin S, Yuh C. Hepatitis B virus X antigen and aflatoxin B1 synergistically cause hepatitis, steatosis and liver hyperplasia in transgenic zebrafish. Acta Histochem. 2013;115:728-39 pubmed publisher
	Yang X, Lu H, Li Z, Bian Q, Qiu L, Li Z, et al. Cytochrome P450 2A13 mediates aflatoxin B1-induced cytotoxicity and apoptosis in human bronchial epithelial cells. Toxicology. 2012;300:138-48 pubmed publisher
	Shirabe K, Toshima T, Taketomi A, Taguchi K, Yoshizumi T, Uchiyama H, et al. Hepatic aflatoxin B1-DNA adducts and TP53 mutations in patients with hepatocellular carcinoma despite low exposure to aflatoxin B1 in southern Japan. Liver Int. 2011;31:1366-72 pubmed publisher
	Long X, Ma Y, Zhou Y, Yao J, Ban F, Huang Y, et al. XPD codon 312 and 751 polymorphisms, and AFB1 exposure, and hepatocellular carcinoma risk. BMC Cancer. 2009;9:400 pubmed publisher
	Besaratinia A, Kim S, Hainaut P, Pfeifer G. In vitro recapitulating of TP53 mutagenesis in hepatocellular carcinoma associated with dietary aflatoxin B1 exposure. Gastroenterology. 2009;137:1127-37, 1137.e1-5 pubmed publisher
	Ochsner U, Bell S, O Leary A, Hoang T, Stone K, Young C, et al. Inhibitory effect of REP3123 on toxin and spore formation in Clostridium difficile, and in vivo efficacy in a hamster gastrointestinal infection model. J Antimicrob Chemother. 2009;63:964-71 pubmed publisher
	Wiszniewski W, Zaremba C, Yatsenko A, Jamrich M, Wensel T, Lewis R, et al. ABCA4 mutations causing mislocalization are found frequently in patients with severe retinal dystrophies. Hum Mol Genet. 2005;14:2769-78 pubmed
	Lunn R, Langlois R, Hsieh L, Thompson C, Bell D. XRCC1 polymorphisms: effects on aflatoxin B1-DNA adducts and glycophorin A variant frequency. Cancer Res. 1999;59:2557-61 pubmed

product information

master code :

NBP1-30032

SKU :

NBP1-30032

product name :

ABCA4 Antibody (3F4) - Azide Free

unit size :

0.1 ml

description :

The ABCA4 Antibody (3F4) - Azide Free from Novus is a mouse monoclonal antibody to ABCA4. This antibody reacts with bovine,canine,feline,human,mouse,xenopus,frog - xenopus (african clawed frog). The ABCA4 Antibody (3F4) - Azide Free has been validated for the following applications: Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Knockout Validated.

target :

ABCA4

category :

Primary Antibodies

buffer :

10 mM HEPES (pH 7.5), 0.15 M NaCl, 0.1 mg/mL BSA, 50% Glycerol

clonality :

Monoclonal

clone :

3F4

conjugate :

Unconjugated

host :

Mouse

immunogen :

Partially purified bovine 220-kDa disc rim protein. Accession # F1MWM0

isotype :

IgG1

purity :

Protein G purified

species :

Bovine,Canine,Feline,Human,Mouse,Xenopus,Frog - Xenopus (African Clawed Frog)

theoretical molecular weight :

220 kDa

gene symbol :

ABCA4

Antibody validation :

Knockout/Knockdown

applications :

Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Knockout Validated

USD :

459 USD

alt names :

ABC10, ABCRRMP, ARMD2DKFZp781N1972, ATP binding cassette transporter, ATP-binding cassette sub-family A member 4, ATP-binding cassette transporter, retinal-specific, ATP-binding cassette, sub-family A (ABC1), member 4, ATP-binding transporter, retina-specific, CORD3, EC 3.6.3, FFMFLJ17534, photoreceptor rim protein, retinal-specific ATP-binding cassette transporter, retina-specific ABC transporter, RIM ABC transporter, RIM protein, RmP, RP19, Stargardt disease protein, STGD, STGD1

storage :

Store at -20C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage