product summary
Loading...
company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
Olig2 Antibody - Azide and BSA Free
catalog :
NBP1-28667
quantity :
0.1 ml (also 0.02 ml)
price :
489 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
5C2
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 59
Reference
Kang M, Yao Y. Oligodendrocyte-derived laminin-γ1 regulates the blood-brain barrier and CNS myelination in mice. Cell Rep. 2024;43:114123 pubmed publisher
Tsai M, Lin W, Chen S, Hsieh M, Nian F, Cheng H, et al. Lissencephaly-associated BAIAP2 variant causes defects in neuronal migration during brain development. Development. 2023;: pubmed publisher
Larrigan S, Joshi S, Mattar P. Divergent phenotypes in constitutive versus conditional mutant mouse models of Sifrim-Hitz-Weiss syndrome. Hum Mol Genet. 2023;32:3361-3373 pubmed publisher
Kim J, Cho S, Youn D, Hong E, Park C, Lee Y, et al. Therapeutic effect of a hydrogel-based neural stem cell delivery sheet for mild traumatic brain injury. Acta Biomater. 2023;167:335-347 pubmed publisher
Zhai J, Xu Y, Wan H, Yan R, Guo J, Skory R, et al. Neurulation of the cynomolgus monkey embryo achieved from 3D blastocyst culture. Cell. 2023;186:2078-2091.e18 pubmed publisher
Huang C, Lee K, Lin P, Nian F, Cheng H, Chang C, et al. Muscleblind-like 2 knockout shifts adducin 1 isoform expression and alters dendritic spine dynamics of cortical neurons during brain development. Neuropathol Appl Neurobiol. 2023;49:e12890 pubmed publisher
Milstead R, Link C, Xu Z, Hoeffer C. TDP-43 knockdown in mouse model of ALS leads to dsRNA deposition, gliosis, and neurodegeneration in the spinal cord. Cereb Cortex. 2022;: pubmed publisher
Xu L, Nirwane A, Xu T, Kang M, Devasani K, Yao Y. Fibroblasts repair blood-brain barrier damage and hemorrhagic brain injury via TIMP2. Cell Rep. 2022;41:111709 pubmed publisher
Ma L, Liang C, Wang J, Chang Q, Wang Y, Zhang W, et al. Reversing lysosome-ribosome circuit dysregulation mitigates C9FTD/ALS neurodegeneration and behaviors. Hum Mol Genet. 2022;: pubmed publisher
Nirwane A, Yao Y. SMAlow/undetectable pericytes differentiate into microglia- and macrophage-like cells in ischemic brain. Cell Mol Life Sci. 2022;79:264 pubmed publisher
Shao E, Chang C, Li Z, Yu X, Ho K, Zhang M, et al. TAU ablation in excitatory neurons and postnatal TAU knockdown reduce epilepsy, SUDEP, and autism behaviors in a Dravet syndrome model. Sci Transl Med. 2022;14:eabm5527 pubmed publisher
Kim D, Kim S, Sung A, Patel N, Wong N, Conboy M, et al. Autologous treatment for ALS with implication for broad neuroprotection. Transl Neurodegener. 2022;11:16 pubmed publisher
Hao W, Luo Q, Menger M, Fassbender K, Liu Y. Treatment With CD52 Antibody Protects Neurons in Experimental Autoimmune Encephalomyelitis Mice During the Recovering Phase. Front Immunol. 2021;12:792465 pubmed publisher
Suter T, Wang J, Meng H, He Z. Utilizing mouse optic nerve crush to examine CNS remyelination. STAR Protoc. 2021;2:100796 pubmed publisher
Satake T. Epstein-Barr virus-based plasmid enables inheritable transgene expression in mouse cerebral cortex. PLoS ONE. 2021;16:e0258026 pubmed publisher
Moroki T, Matsuo S, Hatakeyama H, Hayashi S, Matsumoto I, Suzuki S, et al. Databases for technical aspects of immunohistochemistry: 2021 update. J Toxicol Pathol. 2021;34:161-180 pubmed publisher
Hung T, Liu Y, Wu C, Chen C, Chao H, Yang F, et al. Antenatal low-intensity pulsed ultrasound reduces neurobehavioral deficits and brain injury following dexamethasone-induced intrauterine growth restriction. Brain Pathol. 2021;31:e12968 pubmed publisher
Bartosovic M, Kabbe M, Castelo Branco G. Single-cell CUT&Tag profiles histone modifications and transcription factors in complex tissues. Nat Biotechnol. 2021;39:825-835 pubmed publisher
Yazdankhah M, Ghosh S, Shang P, Stepicheva N, Hose S, Liu H, et al. BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes. Autophagy. 2021;:1-20 pubmed publisher
Wang J, He X, Meng H, Li Y, Dmitriev P, Tian F, et al. Robust Myelination of Regenerated Axons Induced by Combined Manipulations of GPR17 and Microglia. Neuron. 2020;108:876-886.e4 pubmed publisher
Jung D, Pak M, Lee H, Ahn S, Yun Y, Shin Y, et al. Electroacupuncture on the Scalp over the Motor Cortex Ameliorates Behavioral Deficits Following Neonatal Hypoxia-Ischemia in Rats via the Activation of Neural Stem Cells. Life (Basel). 2020;10: pubmed publisher
Cavaccini A, Durkee C, Kofuji P, Tonini R, Araque A. Astrocyte Signaling Gates Long-Term Depression at Corticostriatal Synapses of the Direct Pathway. J Neurosci. 2020;40:5757-5768 pubmed publisher
Zhang H, Chen W, Tan Z, Zhang L, Dong Z, Cui W, et al. A Role of Low-Density Lipoprotein Receptor-Related Protein 4 (LRP4) in Astrocytic Aβ Clearance. J Neurosci. 2020;40:5347-5361 pubmed publisher
Barodia S, McMeekin L, Creed R, Quinones E, Cowell R, Goldberg M. PINK1 phosphorylates ubiquitin predominantly in astrocytes. NPJ Parkinsons Dis. 2019;5:29 pubmed publisher
Epperly M, Fisher R, Rigatti L, Watkins S, Zhang X, Hou W, et al. Amelioration of Amyotrophic Lateral Sclerosis in SOD1G93A Mice by M2 Microglia from Transplanted Marrow. In Vivo. 2019;33:675-688 pubmed publisher
Lozano D, Choe T, Cepurna W, Morrison J, Johnson E. Early Optic Nerve Head Glial Proliferation and Jak-Stat Pathway Activation in Chronic Experimental Glaucoma. Invest Ophthalmol Vis Sci. 2019;60:921-932 pubmed publisher
Meister Broekema M, Freilich R, Jagadeesan C, Rauch J, Bengoechea R, Motley W, et al. Myopathy associated BAG3 mutations lead to protein aggregation by stalling Hsp70 networks. Nat Commun. 2018;9:5342 pubmed publisher
Gotoh H, Wood W, Patel K, Factor D, Boshans L, Nomura T, et al. NG2 expression in NG2 glia is regulated by binding of SoxE and bHLH transcription factors to a Cspg4 intronic enhancer. Glia. 2018;66:2684-2699 pubmed publisher
Janardhan K, Jensen H, Clayton N, Herbert R. Immunohistochemistry in Investigative and Toxicologic Pathology. Toxicol Pathol. 2018;46:488-510 pubmed publisher
Sumiyoshi K, Koso H, Watanabe S. Spontaneous development of intratumoral heterogeneity in a transposon-induced mouse model of glioma. Cancer Sci. 2018;109:1513-1523 pubmed publisher
Zuo H, Wood W, Sherafat A, Hill R, Lu Q, Nishiyama A. Age-Dependent Decline in Fate Switch from NG2 Cells to Astrocytes After Olig2 Deletion. J Neurosci. 2018;38:2359-2371 pubmed publisher
Yu M, Tanese N. Huntingtin Is Required for Neural But Not Cardiac/Pancreatic Progenitor Differentiation of Mouse Embryonic Stem Cells In vitro. Front Cell Neurosci. 2017;11:33 pubmed publisher
Furukawa S, Nagaike M, Ozaki K. Databases for technical aspects of immunohistochemistry. J Toxicol Pathol. 2017;30:79-107 pubmed publisher
Barnard R, Regan D, Hansen R, Maycotte P, Thorburn A, Gustafson D. Autophagy Inhibition Delays Early but Not Late-Stage Metastatic Disease. J Pharmacol Exp Ther. 2016;358:282-93 pubmed publisher
Aumailley L, Garand C, Dubois M, Johnson F, Marette A, Lebel M. Metabolic and Phenotypic Differences between Mice Producing a Werner Syndrome Helicase Mutant Protein and Wrn Null Mice. PLoS ONE. 2015;10:e0140292 pubmed publisher
Milan E, Perini T, Resnati M, Orfanelli U, Oliva L, Raimondi A, et al. A plastic SQSTM1/p62-dependent autophagic reserve maintains proteostasis and determines proteasome inhibitor susceptibility in multiple myeloma cells. Autophagy. 2015;11:1161-78 pubmed publisher
Mendez G, Cilli D, Berardinelli F, Viganotti M, Ascenzi P, Tanzarella C, et al. Cleavage of the BRCT tandem domains of nibrin by the 657del5 mutation affects the DNA damage response less than the Arg215Trp mutation. IUBMB Life. 2012;64:853-61 pubmed publisher
Daniel J, Pellegrini M, Lee B, Guo Z, Filsuf D, Belkina N, et al. Loss of ATM kinase activity leads to embryonic lethality in mice. J Cell Biol. 2012;198:295-304 pubmed publisher
Hou Y, Toh M, Wang X. NBS1 deficiency promotes genome instability by affecting DNA damage signaling pathway and impairing telomere integrity. Cell Biochem Funct. 2012;30:233-42 pubmed publisher
Vogel R, Seyffert M, Strasser R, de Oliveira A, Dresch C, Glauser D, et al. Adeno-associated virus type 2 modulates the host DNA damage response induced by herpes simplex virus 1 during coinfection. J Virol. 2012;86:143-55 pubmed publisher
Rankin A, Sarkar S, Faller D. Mechanism of T-oligo-induced cell cycle arrest in Mia-PaCa pancreatic cancer cells. J Cell Physiol. 2012;227:2586-94 pubmed publisher
Gapud E, Dorsett Y, Yin B, Callen E, Bredemeyer A, Mahowald G, et al. Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation. Proc Natl Acad Sci U S A. 2011;108:2022-7 pubmed publisher
Cam H, Easton J, High A, Houghton P. mTORC1 signaling under hypoxic conditions is controlled by ATM-dependent phosphorylation of HIF-1α. Mol Cell. 2010;40:509-20 pubmed publisher
Craig A, Holcakova J, Finlan L, Nekulova M, Hrstka R, Gueven N, et al. DeltaNp63 transcriptionally regulates ATM to control p53 Serine-15 phosphorylation. Mol Cancer. 2010;9:195 pubmed publisher
Alimonti A, Nardella C, Chen Z, Clohessy J, Carracedo A, Trotman L, et al. A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis. J Clin Invest. 2010;120:681-93 pubmed publisher
Gonzalez Suarez I, Redwood A, Perkins S, Vermolen B, Lichtensztejin D, Grotsky D, et al. Novel roles for A-type lamins in telomere biology and the DNA damage response pathway. EMBO J. 2009;28:2414-27 pubmed publisher
Efeyan A, Murga M, Martinez Pastor B, Ortega Molina A, Soria R, Collado M, et al. Limited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression. PLoS ONE. 2009;4:e5475 pubmed publisher
Siehler S, Schrauder M, Gerischer U, Cantor S, Marra G, Wiesmuller L. Human MutL-complexes monitor homologous recombination independently of mismatch repair. DNA Repair (Amst). 2009;8:242-52 pubmed publisher
Ariumi Y, Kuroki M, Dansako H, Abe K, Ikeda M, Wakita T, et al. The DNA damage sensors ataxia-telangiectasia mutated kinase and checkpoint kinase 2 are required for hepatitis C virus RNA replication. J Virol. 2008;82:9639-46 pubmed publisher
Sun Y, Xu Y, Roy K, Price B. DNA damage-induced acetylation of lysine 3016 of ATM activates ATM kinase activity. Mol Cell Biol. 2007;27:8502-9 pubmed
Fernandes N, Sun Y, Price B. Activation of the kinase activity of ATM by retinoic acid is required for CREB-dependent differentiation of neuroblastoma cells. J Biol Chem. 2007;282:16577-84 pubmed
Chen J, Ozanne S. Deep senescent human fibroblasts show diminished DNA damage foci but retain checkpoint capacity to oxidative stress. FEBS Lett. 2006;580:6669-73 pubmed
Sun Y, Jiang X, Chen S, Price B. Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation. FEBS Lett. 2006;580:4353-6 pubmed
Roy K, Wang L, Makrigiorgos G, Price B. Methylation of the ATM promoter in glioma cells alters ionizing radiation sensitivity. Biochem Biophys Res Commun. 2006;344:821-6 pubmed
Jiang X, Sun Y, Chen S, Roy K, Price B. The FATC domains of PIKK proteins are functionally equivalent and participate in the Tip60-dependent activation of DNA-PKcs and ATM. J Biol Chem. 2006;281:15741-6 pubmed
Shiotani B, Kobayashi M, Watanabe M, Yamamoto K, Sugimura T, Wakabayashi K. Involvement of the ATR- and ATM-dependent checkpoint responses in cell cycle arrest evoked by pierisin-1. Mol Cancer Res. 2006;4:125-33 pubmed
Sun Y, Jiang X, Chen S, Fernandes N, Price B. A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM. Proc Natl Acad Sci U S A. 2005;102:13182-7 pubmed
Fernandes N, Sun Y, Chen S, Paul P, Shaw R, Cantley L, et al. DNA damage-induced association of ATM with its target proteins requires a protein interaction domain in the N terminus of ATM. J Biol Chem. 2005;280:15158-64 pubmed
Lai C, Chun H, Nahas S, Mitui M, Gamo K, Du L, et al. Correction of ATM gene function by aminoglycoside-induced read-through of premature termination codons. Proc Natl Acad Sci U S A. 2004;101:15676-81 pubmed
product information
master code :
NBP1-28667
SKU :
NBP1-28667
product name :
Olig2 Antibody - Azide and BSA Free
unit size :
0.1 ml (also 0.02 ml)
description :
The Olig2 Antibody - Azide and BSA Free from Novus is a rabbit polyclonal antibody to Olig2. This antibody reacts with human,mouse,rat. The Olig2 Antibody - Azide and BSA Free has been validated for the following applications: Immunohistochemistry,IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry Free-Floating,Immunocytochemistry/ Immunofluorescence,Immunoprecipitation.
target :
Olig2
category :
Primary Antibodies
buffer :
200 mM Tris (pH 8.0), 0.1 M Glycine
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Recombinant mouse Olig2. Accession # Q9EQW6
isotype :
IgG
purity :
Protein A purified
species :
Human,Mouse,Rat
specificity :
Specific for endogenous levels of the ~32 kDa Olig2 protein
theoretical molecular weight :
27 kDa
gene symbol :
OLIG2
accessionNumbers :
Q9EQW6
applications :
IF/IHC,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry Free-Floating,Immunocytochemistry/ Immunofluorescence,Immunoprecipitation
USD :
489 USD
alt names :
BHLHB1, BHLHE19, Class B basic helix-loop-helix protein 1, Class E basic helix-loop-helix protein 19, human protein kinase C-binding protein RACK17, OLIGO2, oligodendrocyte lineage transcription factor 2, oligodendrocyte transcription factor 2, oligodendrocyte-specific bHLH transcription factor 2, protein kinase C binding protein 2, Protein kinase C-binding protein 2, Protein kinase C-binding protein RACK17, RACK17helix-loop-helix protein, class B, 1
storage :
Store at -20C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.