Bax Antibody (6A7) - Azide and BSA Free | Novus Biologicals NBP1-28566 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

Bax Antibody (6A7) - Azide and BSA Free

catalog :

NBP1-28566

quantity :

0.1 mg

price :

409 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6A7

reactivity :

human, mouse, rat, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Novus Biologicals product webpage

citations: 26

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 4c	Yu C, Li C, Chen I, Lai M, Lin Z, Korla P, et al. YWHAZ amplification/overexpression defines aggressive bladder cancer and contributes to chemo-/radio-resistance by suppressing caspase-mediated apoptosis. J Pathol. 2019;248:476-487 pubmed publisher
western blot; rat; 1:500; loading ...; fig 7c	Xie Z, Enkhjargal B, Wu L, Zhou K, Sun C, Hu X, et al. Exendin-4 attenuates neuronal death via GLP-1R/PI3K/Akt pathway in early brain injury after subarachnoid hemorrhage in rats. Neuropharmacology. 2018;128:142-151 pubmed publisher
	Yang G, Xiang J, Yang X, Liu X, Li Y, Li L, et al. Nuclear translocation of SIRT4 mediates deacetylation of U2AF2 to modulate renal fibrosis through alternative splicing-mediated upregulation of CCN2. elife. 2024;13: pubmed publisher
	Victorelli S, Salmonowicz H, Chapman J, Martini H, Vizioli M, Riley J, et al. Apoptotic stress causes mtDNA release during senescence and drives the SASP. Nature. 2023;622:627-636 pubmed publisher
	Ghosh S, Singh R, Vanwinkle Z, Guo H, Vemula P, Goel A, et al. Microbial metabolite restricts 5-fluorouracil-resistant colonic tumor progression by sensitizing drug transporters via regulation of FOXO3-FOXM1 axis. Theranostics. 2022;12:5574-5595 pubmed publisher
	Simbulan Rosenthal C, Haribabu Y, Vakili S, Kuo L, Clark H, DOUGHERTY R, et al. Employing CRISPR-Cas9 to Generate CD133 Synthetic Lethal Melanoma Stem Cells. Int J Mol Sci. 2022;23: pubmed publisher
	Mehanna E, Khalaf S, Mesbah N, Abo Elmatty D, Hafez M. Anti-oxidant, anti-apoptotic, and mitochondrial regulatory effects of selenium nanoparticles against vancomycin induced nephrotoxicity in experimental rats. Life Sci. 2022;288:120098 pubmed publisher
	Hale B, Li Y, Adur M, Keating A, Baumgard L, Ross J. Characterization of the effects of heat stress on autophagy induction in the pig oocyte. Reprod Biol Endocrinol. 2021;19:107 pubmed publisher
	Song B, Wei D, Yin G, Song X, Wang S, Jia S, et al. Critical role of SIRT1 upregulation on the protective effect of lncRNA ANRIL against hypoxia/reoxygenation injury in H9c2 cardiomyocytes. Mol Med Rep. 2021;24: pubmed publisher
	Gül H, Ilhan N, Ilhan N, Ozercan I, Kuloglu T. The combined effect of pomegranate extract and tangeretin on the DMBA-induced breast cancer model. J Nutr Biochem. 2021;89:108566 pubmed publisher
	Arman T, Lynch K, Goedken M, Clarke J. Sub-chronic microcystin-LR renal toxicity in rats fed a high fat/high cholesterol diet. Chemosphere. 2021;269:128773 pubmed publisher
	Sun F, Du J, Li H, Hao S, Zhao G, Lu F. FABP4 inhibitor BMS309403 protects against hypoxia-induced H9c2 cardiomyocyte apoptosis through attenuating endoplasmic reticulum stress. J Cell Mol Med. 2020;24:11188-11197 pubmed publisher
	Tang H, Gamdzyk M, Huang L, Gao L, Lenahan C, Kang R, et al. Delayed recanalization after MCAO ameliorates ischemic stroke by inhibiting apoptosis via HGF/c-Met/STAT3/Bcl-2 pathway in rats. Exp Neurol. 2020;330:113359 pubmed publisher
	Sun C, Enkhjargal B, Reis C, Zhou K, Xie Z, Wu L, et al. Osteopontin attenuates early brain injury through regulating autophagy-apoptosis interaction after subarachnoid hemorrhage in rats. CNS Neurosci Ther. 2019;25:1162-1172 pubmed publisher
	Gong X, Xu B, Zi L, Chen X. miR-625 reverses multidrug resistance in gastric cancer cells by directly targeting ALDH1A1. Cancer Manag Res. 2019;11:6615-6624 pubmed publisher
	Zheng W, Matei N, Pang J, Luo X, Song Z, Tang J, et al. Delayed recanalization at 3 days after permanent MCAO attenuates neuronal apoptosis through FGF21/FGFR1/PI3K/Caspase-3 pathway in rats. Exp Neurol. 2019;320:113007 pubmed publisher
	Jeong J, Horwath J, Simonyan H, Blackmore K, Butler S, Young C. Subfornical organ insulin receptors tonically modulate cardiovascular and metabolic function. Physiol Genomics. 2019;51:333-341 pubmed publisher
	Rosales M, Shu D, Iacovelli J, Saint Geniez M. Loss of PGC-1α in RPE induces mesenchymal transition and promotes retinal degeneration. Life Sci Alliance. 2019;2: pubmed publisher
	Ahmad S, Rogers A, Chen M, Dixit R, Adnani L, Frankiw L, et al. Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors. Nat Commun. 2019;10:2000 pubmed publisher
	Zhou X, Liu S, Lin X, Xu L, Mao X, Liu J, et al. Metformin Inhibit Lung Cancer Cell Growth and Invasion in Vitro as Well as Tumor Formation in Vivo Partially by Activating PP2A. Med Sci Monit. 2019;25:836-846 pubmed publisher
	Zhao L, Zhang J, Sherchan P, Krafft P, Zhao W, Wang S, et al. Administration of rCTRP9 Attenuates Neuronal Apoptosis Through AdipoR1/PI3K/Akt Signaling Pathway after ICH in Mice. Cell Transplant. 2019;28:756-766 pubmed publisher
	Xu D, Chen P, Wang B, Wang Y, Miao N, Yin F, et al. NIX-mediated mitophagy protects against proteinuria-induced tubular cell apoptosis and renal injury. Am J Physiol Renal Physiol. 2019;316:F382-F395 pubmed publisher
	Zhao G, Zhao S, Liu J, Wu J, He H, Ding X, et al. Cytokeratin 19 promoter directs the expression of Cre recombinase in various epithelia of transgenic mice. Oncotarget. 2017;8:18303-18311 pubmed publisher
	Tao L, Xiang D, Xie Y, Bronson R, Li Z. Induced p53 loss in mouse luminal cells causes clonal expansion and development of mammary tumours. Nat Commun. 2017;8:14431 pubmed publisher
	Shi X, Xu L, Doycheva D, Tang J, Yan M, Zhang J. Sestrin2, as a negative feedback regulator of mTOR, provides neuroprotection by activation AMPK phosphorylation in neonatal hypoxic-ischemic encephalopathy in rat pups. J Cereb Blood Flow Metab. 2017;37:1447-1460 pubmed publisher
	Barreto Vianna A, Aguila M, Mandarim de Lacerda C. Effects of liraglutide in hypothalamic arcuate nucleus of obese mice. Obesity (Silver Spring). 2016;24:626-33 pubmed publisher

product information

master code :

NBP1-28566

SKU :

NBP1-28566

product name :

Bax Antibody (6A7) - Azide and BSA Free

unit size :

0.1 mg

description :

The Bax Antibody (6A7) - Azide and BSA Free from Novus is a mouse monoclonal antibody to Bax. This antibody reacts with bovine,human,monkey,mouse,porcine,rat. The Bax Antibody (6A7) - Azide and BSA Free has been validated for the following applications: Western Blot,Co-IP,IF/IHC,Immunohistochemistry-Paraffin,Functional Assay,Immunohistochemistry,Immunohistochemistry-Frozen,Functional.

target :

Bax

category :

Primary Antibodies

buffer :

Borate buffered saline, pH 8.2

clonality :

Monoclonal

clone :

6A7

concentration :

0.1 mg/ml

conjugate :

Unconjugated

host :

Mouse

immunogen :

KLH-conjugated peptide corresponding to amino acids 12-24 located near the N-terminus common to human, mouse and rat Bax.

isotype :

IgG1 Kappa

purity :

Protein A or G purified

species :

Bovine,Human,Monkey,Mouse,Porcine,Rat

specificity :

The monoclonal antibody 6A7 reacts with human, mouse and rat Bax but does not bind the soluble cytosolic form of Bax; however, treatment of cells with non-ionic detergents exposes the epitope and allows binding of 6A7 to monomeric forms of Bax but not Bax complexed with either Bcl-2 or Bcl-xL

gene symbol :

BAX

accessionNumbers :

Q07812

applications :

Co-IP,IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Functional Assay,Immunohistochemistry,Immunohistochemistry-Frozen,Functional

USD :

409 USD

alt names :

apoptosis regulator BAX, BCL2-associated X protein, Bcl2-L-4, BCL2L4bcl2-L-4, Bcl-2-like protein 4

storage :

Store at 4C. Do not freeze.

more info or order :

Novus Biologicals product webpage