product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
LC3A Antibody - BSA Free
catalog :
NBP1-19167
quantity :
0.1 ml (also 0.025 ml)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, bovine, zebrafish
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 36
Published Application/Species/Sample/DilutionReference
  • western blot; human
Campos T, Ziehe J, Palma M, Escobar D, Tapia J, Pincheira R, et al. Rheb promotes cancer cell survival through p27Kip1-dependent activation of autophagy. Mol Carcinog. 2016;55:220-9 pubmed publisher
Alshammari T, Alghamdi H, Green T, Niazy A, Alkahdar L, Alrasheed N, et al. Assessing the role of toll-like receptor in isolated, standard and enriched housing conditions. PLoS ONE. 2019;14:e0222818 pubmed publisher
Gu R, Huang T, Xiao J, Liao Z, Li J, Lan H, et al. The IRE1α Arm of UPR Regulates Muscle Cells Immune Characters by Restraining p38 MAPK Activation. Front Physiol. 2019;10:1198 pubmed publisher
Huang Y, Zhou F, Xiao Y, Shen C, Liu K, Zhao B. TLR7 mediates increased vulnerability to ischemic acute kidney injury in diabetes. Rev Assoc Med Bras (1992). 2019;65:1067-1073 pubmed publisher
Kasurinen A, Hagstrom J, Laitinen A, Kokkola A, Böckelman C, Haglund C. Evaluation of toll-like receptors as prognostic biomarkers in gastric cancer: high tissue TLR5 predicts a better outcome. Sci Rep. 2019;9:12553 pubmed publisher
Lanki M, Seppänen H, Mustonen H, Hagstrom J, Haglund C. Toll-like receptor 1 predicts favorable prognosis in pancreatic cancer. PLoS ONE. 2019;14:e0219245 pubmed publisher
Ruuskanen M, Leivo I, Minn H, Vahlberg T, Haglund C, Hagstrom J, et al. Expression of toll-like receptors in non-endemic nasopharyngeal carcinoma. BMC Cancer. 2019;19:624 pubmed publisher
Haeggblom L, Näsman A, Ramqvist T, Haglund C, Hagstrom J, Mäkitie A, et al. TLR5 and TLR7 are differentially expressed in human papillomavirus-positive and negative base of tongue squamous cell carcinoma, and TLR7 may have an independent prognostic influence. Acta Otolaryngol. 2019;139:206-210 pubmed publisher
Kapelouzou A, Kontogiannis C, Tsilimigras D, Georgiopoulos G, Kaklamanis L, Tsourelis L, et al. Differential expression patterns of Toll Like Receptors and Interleukin-37 between calcific aortic and mitral valve cusps in humans. Cytokine. 2019;116:150-160 pubmed publisher
Korski K, Kubli D, Wang B, Khalafalla F, Monsanto M, Firouzi F, et al. Hypoxia Prevents Mitochondrial Dysfunction and Senescence in Human c-Kit+ Cardiac Progenitor Cells. Stem Cells. 2019;37:555-567 pubmed publisher
Blanchard E, Loomis K, Bhosle S, Vanover D, Baumhof P, Pitard B, et al. Proximity Ligation Assays for In Situ Detection of Innate Immune Activation: Focus on In Vitro-Transcribed mRNA. Mol Ther Nucleic Acids. 2018;14:52-66 pubmed publisher
Sakata K, Nakayamada S, Miyazaki Y, Kubo S, Ishii A, Nakano K, et al. Up-Regulation of TLR7-Mediated IFN-α Production by Plasmacytoid Dendritic Cells in Patients With Systemic Lupus Erythematosus. Front Immunol. 2018;9:1957 pubmed publisher
Jiang Z, Bo L, Meng Y, Wang C, Chen T, Wang C, et al. Overexpression of homeodomain-interacting protein kinase 2 (HIPK2) attenuates sepsis-mediated liver injury by restoring autophagy. Cell Death Dis. 2018;9:847 pubmed publisher
Loomis K, Lindsay K, Zurla C, Bhosle S, Vanover D, Blanchard E, et al. In Vitro Transcribed mRNA Vaccines with Programmable Stimulation of Innate Immunity. Bioconjug Chem. 2018;29:3072-3083 pubmed publisher
Aravanis C, Kapelouzou A, Vagios S, Tsilimigras D, Katsimpoulas M, Moris D, et al. Toll-Like Receptors -2, -3, -4 and -7 Expression Patterns in the Liver of a CLP-Induced Sepsis Mouse Model. J Invest Surg. 2018;:1-9 pubmed publisher
Yang A, Herter Sprie G, Zhang H, Lin E, Biancur D, Wang X, et al. Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms. Cancer Discov. 2018;8:276-287 pubmed publisher
Murayama G, Furusawa N, Chiba A, Yamaji K, Tamura N, Miyake S. Enhanced IFN-? production is associated with increased TLR7 retention in the lysosomes of palasmacytoid dendritic cells in systemic lupus erythematosus. Arthritis Res Ther. 2017;19:234 pubmed publisher
Auger J, Santinón A, Roy D, Mossman K, Xu J, Segura M, et al. Type I Interferon Induced by Streptococcus suis Serotype 2 is Strain-Dependent and May Be Beneficial for Host Survival. Front Immunol. 2017;8:1039 pubmed publisher
Jouhi L, Mohamed H, Mäkitie A, Remes S, Haglund C, Atula T, et al. Toll-like receptor 5 and 7 expression may impact prognosis of HPV-positive oropharyngeal squamous cell carcinoma patients. Cancer Immunol Immunother. 2017;66:1619-1629 pubmed publisher
Feng Y, Zou L, Yan D, Chen H, Xu G, Jian W, et al. Extracellular MicroRNAs Induce Potent Innate Immune Responses via TLR7/MyD88-Dependent Mechanisms. J Immunol. 2017;199:2106-2117 pubmed publisher
To E, Vlahos R, Luong R, Halls M, Reading P, King P, et al. Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy. Nat Commun. 2017;8:69 pubmed publisher
Larsson O, Tengroth L, Xu Y, Uddman R, Kumlien Georén S, Cardell L. Substance P represents a novel first-line defense mechanism in the nose. J Allergy Clin Immunol. 2018;141:128-136.e3 pubmed publisher
Daley D, Zambirinis C, Seifert L, Akkad N, Mohan N, Werba G, et al. ?? T Cells Support Pancreatic Oncogenesis by Restraining ?? T Cell Activation. Cell. 2016;166:1485-1499.e15 pubmed publisher
Li X, Liu F, Zhang X, Shi G, Ren J, Ji J, et al. Notch-Hes-1 axis controls TLR7-mediated autophagic death of macrophage via induction of P62 in mice with lupus. Cell Death Dis. 2016;7:e2341 pubmed publisher
Huang A, Wu S. The effect of imiquimod on taste bud calcium transients and transmitter secretion. Br J Pharmacol. 2016;173:3121-3133 pubmed publisher
Kohler L, Reed S, Sarraf S, Arteaga D, Newton H, Roy C. Effector Protein Cig2 Decreases Host Tolerance of Infection by Directing Constitutive Fusion of Autophagosomes with the Coxiella-Containing Vacuole. MBio. 2016;7: pubmed publisher
Zeng M, Nourishirazi E, Guinet E, Nouri Shirazi M. The genetic background influences the cellular and humoral immune responses to vaccines. Clin Exp Immunol. 2016;186:190-204 pubmed publisher
Jeon Y, Kim C, Koh J, Chung D, Ha G. Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination. Oncotarget. 2016;7:41811-41824 pubmed publisher
Saito T, Asai K, Sato S, Hayashi M, Adachi A, Sasaki Y, et al. Autophagic vacuoles in cardiomyocytes of dilated cardiomyopathy with initially decompensated heart failure predict improved prognosis. Autophagy. 2016;12:579-87 pubmed publisher
Helley M, Abate W, Jackson S, Bennett J, Thompson S. The expression of Toll-like receptor 4, 7 and co-receptors in neurochemical sub-populations of rat trigeminal ganglion sensory neurons. Neuroscience. 2015;310:686-98 pubmed publisher
Renkonen J, Toppila Salmi S, Joenväärä S, Mattila P, Parviainen V, Hagström J, et al. Expression of Toll-like receptors in nasal epithelium in allergic rhinitis. APMIS. 2015;123:716-25 pubmed publisher
Renkonen S, Cardell L, Mattila P, Lundberg M, Haglund C, Hagström J, et al. Toll-like receptors 3, 7, and 9 in Juvenile nasopharyngeal angiofibroma. APMIS. 2015;123:439-44 pubmed publisher
Saito K, Kukita K, Kutomi G, Okuya K, Asanuma H, Tabeya T, et al. Heat shock protein 90 associates with Toll-like receptors 7/9 and mediates self-nucleic acid recognition in SLE. Eur J Immunol. 2015;45:2028-41 pubmed publisher
Jouhi L, Koljonen V, Böhling T, Haglund C, Hagström J. The expression of Toll-like receptors 2, 4, 5, 7 and 9 in Merkel cell carcinoma. Anticancer Res. 2015;35:1843-9 pubmed
Milara J, Morell A, Ballester B, Sanz C, Freire J, Qian X, et al. Roflumilast improves corticosteroid resistance COPD bronchial epithelial cells stimulated with toll like receptor 3 agonist. Respir Res. 2015;16:12 pubmed publisher
Mäkinen L, Atula T, Häyry V, Jouhi L, Datta N, Lehtonen S, et al. Predictive role of Toll-like receptors 2, 4, and 9 in oral tongue squamous cell carcinoma. Oral Oncol. 2015;51:96-102 pubmed publisher
product information
master code :
NBP1-19167
SKU :
NBP1-19167
product name :
LC3A Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The LC3A Antibody - BSA Free from Novus is a rabbit polyclonal antibody to LC3A. This antibody reacts with bovine,human,mouse,rat,zebrafish. The LC3A Antibody - BSA Free has been validated for the following applications: IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Immunohistochemistry,Simple Western.
target :
LC3A
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Partial recombinant protein made to an N-terminal portion of the human LC3A protein [Swiss-Prot# Q9H492].
isotype :
IgG
purity :
Immunogen affinity purified
species :
Bovine,Human,Mouse,Rat,Zebrafish
specificity :
Although specificity between this LC3A Antibody and LC3B has not been tested, this antibody was created to a peptide that has 100% identity to LC3A and 62% identity to LC3B
theoretical molecular weight :
14 kDa
gene symbol :
MAP1LC3A
Antibody validation :
Biological Validation
accessionNumbers :
Q9H492
applications :
IF/IHC,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Immunohistochemistry,Simple Western
USD :
409 USD
alt names :
ATG8E, Autophagy-related protein LC3 A, Autophagy-related ubiquitin-like modifier LC3 A, LC3, LC3A, MAP1 light chain 3-like protein 1, MAP1A/1B light chain 3 A, MAP1A/MAP1B LC3 A, MAP1A/MAP1B light chain 3 A, MAP1ALC3, MAP1BLC3, MAP1LC3A, Microtubule-associated protein 1 light chain 3 alpha, microtubule-associated proteins 1A/1B light chain 3, microtubule-associated proteins 1A/1B light chain 3A
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.