product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
AMBRA1 Antibody - BSA Free
catalog :
NBP1-07124
quantity :
0.2 ml (also 0.05 ml)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 5
Reference
Ram xed rez Pardo I, Villarejo Zori B, Jim xe9 nez Loygorri J, Sierra Filardi E, Alonso Gil S, Mari xf1 o G, et al. Ambra1 haploinsufficiency in CD1 mice results in metabolic alterations and exacerbates age-associated retinal degeneration. Autophagy. 2023;19:784-804 pubmed publisher
Li L, Zuo X, Liu D, Luo H, Zhang H, Peng Q, et al. Plasma exosomal RNAs has potential as both clinical biomarkers and therapeutic targets of dermatomyositis. Rheumatology (Oxford). 2021;: pubmed publisher
Antonioli M, Pagni B, Vescovo T, Ellis R, Cosway B, Rollo F, et al. HPV sensitizes OPSCC cells to cisplatin-induced apoptosis by inhibiting autophagy through E7-mediated degradation of AMBRA1. Autophagy. 2020;:1-14 pubmed publisher
Nobili A, Krashia P, Cordella A, La Barbera L, Dell Acqua M, Caruso A, et al. Ambra1 Shapes Hippocampal Inhibition/Excitation Balance: Role in Neurodevelopmental Disorders. Mol Neurobiol. 2018;55:7921-7940 pubmed publisher
Ugun Klusek A, Tatham M, Elkharaz J, Constantin Teodosiu D, Lawler K, Mohamed H, et al. Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway. Cell Death Dis. 2017;8:e2531 pubmed publisher
product information
master code :
NBP1-07124
SKU :
NBP1-07124
product name :
AMBRA1 Antibody - BSA Free
unit size :
0.2 ml (also 0.05 ml)
description :
The AMBRA1 Antibody - BSA Free from Novus is a rabbit polyclonal antibody to AMBRA1. This antibody reacts with human,mouse,rat. The AMBRA1 Antibody - BSA Free has been validated for the following applications: Western Blot,IF/IHC,Immunomicroscopy,Immunocytochemistry/ Immunofluorescence,ELISA,Immunohistochemistry,Immunohistochemistry-Paraffin.
target :
AMBRA1
category :
Primary Antibodies
buffer :
PBS and 30% Glycerol
clonality :
Polyclonal
concentration :
1.0 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
A synthetic peptide derived from mouse activating molecule in Beclin 1-regulated/AMBRA1 protein sequence [amino acids range 1175-1250] [UniProt # A2AH22]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Human,Mouse,Rat
gene symbol :
AMBRA1
accessionNumbers :
A2AH22
applications :
IF/IHC,Western Blot,Immunomicroscopy,Immunocytochemistry/ Immunofluorescence,ELISA,Immunohistochemistry,Immunohistochemistry-Paraffin
USD :
409 USD
alt names :
activating molecule in BECN1-regulated autophagy protein 1, autophagy/beclin-1 regulator 1, DCAF3, DDB1 and CUL4 associated factor 3, FLJ20294, KIAA1736activating molecule in beclin-1-regulated autophagy, MGC33725, WD repeat domain 94, WDR94
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.