product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
LDLR Antibody - BSA Free
catalog :
NBP1-06709
quantity :
0.1 ml (also 0.025 ml)
price :
519 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, dogs, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 14
Reference
Pan X, Hu S, Xu Y, Gopoju R, Zhu Y, Cassim Bawa F, et al. Krüppel-like factor 10 protects against metabolic dysfunction-associated steatohepatitis by regulating HNF4α-mediated metabolic pathways. Metabolism. 2024;155:155909 pubmed publisher
Hu S, Zhu Y, Zhao X, Li R, Shao G, Gong D, et al. Hepatocytic lipocalin-2 controls HDL metabolism and atherosclerosis via Nedd4-1-SR-BI axis in mice. Dev Cell. 2023;58:2326-2337.e5 pubmed publisher
Thapa K, Kadiri J, Saukkonen K, Pennanen I, Ghimire B, Cai M, et al. Melanocortin 1 receptor regulates cholesterol and bile acid metabolism in the liver. elife. 2023;12: pubmed publisher
O Neill K, Kuo L, Williams M, Lind H, Crump L, Hammond N, et al. NPC1 Confers Metabolic Flexibility in Triple Negative Breast Cancer. Cancers (Basel). 2022;14: pubmed publisher
Ho W, Chang J, Lim K, Cazenave Gassiot A, Nguyen A, Foo J, et al. TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination. J Cell Biol. 2021;220: pubmed publisher
Xu Y, Li Y, Jadhav K, Pan X, Zhu Y, Hu S, et al. Hepatocyte ATF3 protects against atherosclerosis by regulating HDL and bile acid metabolism. Nat Metab. 2021;3:59-74 pubmed publisher
Kohlhaas J, Jäger M, Lust L, de la Torre C, Hecker M, Korff T. Endothelial cells control vascular smooth muscle cell cholesterol levels by regulating 24-dehydrocholesterol reductase expression. Exp Cell Res. 2021;399:112446 pubmed publisher
He B, Moreau R. R-α-Lipoic Acid and 4-Phenylbutyric Acid Have Distinct Hypolipidemic Mechanisms in Hepatic Cells. Biomedicines. 2020;8: pubmed publisher
Xu Y, Zhu Y, Bawa F, Hu S, Pan X, Yin L, et al. Hepatocyte-Specific Expression of Human Carboxylesterase 1 Attenuates Diet-Induced Steatohepatitis and Hyperlipidemia in Mice. Hepatol Commun. 2020;4:527-539 pubmed publisher
Biswas L, Zeng Z, Graham A, Shu X. Gypenosides mediate cholesterol efflux and suppress oxidized LDL induced inflammation in retinal pigment epithelium cells. Exp Eye Res. 2020;191:107931 pubmed publisher
Sharma B, Gupta V, Dahiya D, Kumar H, Vaiphei K, Agnihotri N. Clinical relevance of cholesterol homeostasis genes in colorectal cancer. Biochim Biophys Acta Mol Cell Biol Lipids. 2019;1864:1314-1327 pubmed publisher
Xu J, Xu Y, Xu Y, Yin L, Zhang Y. Global inactivation of carboxylesterase 1 (Ces1/Ces1g) protects against atherosclerosis in Ldlr -/- mice. Sci Rep. 2017;7:17845 pubmed publisher
Yang Y, Yang Q, Yang J, Ma Y, Ding G. Angiotensin II induces cholesterol accumulation and injury in podocytes. Sci Rep. 2017;7:10672 pubmed publisher
Sun L, Yang X, Li Q, Zeng P, Liu Y, Liu L, et al. Activation of Adiponectin Receptor Regulates Proprotein Convertase Subtilisin/Kexin Type 9 Expression and Inhibits Lesions in ApoE-Deficient Mice. Arterioscler Thromb Vasc Biol. 2017;37:1290-1300 pubmed publisher
product information
master code :
NBP1-06709
SKU :
NBP1-06709
product name :
LDLR Antibody - BSA Free
unit size :
0.1 ml (also 0.025 ml)
description :
The LDLR Antibody - BSA Free from Novus is a rabbit polyclonal antibody to LDLR. This antibody reacts with bovine,canine,human,mouse. The LDLR Antibody - BSA Free has been validated for the following applications: Immunohistochemistry-Paraffin,IF/IHC,Simple Western,Western Blot,In vitro assay,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Knockout Validated.
target :
LDLR
category :
Primary Antibodies
buffer :
PBS
clonality :
Polyclonal
concentration :
1 mg/ml
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Synthetic peptide made to an internal portion of the human LDL Receptor protein (within residues 500-550). [Swiss-Prot# P01130]
isotype :
IgG
purity :
Immunogen affinity purified
species :
Bovine,Canine,Human,Mouse
specificity :
This is specific for both the unglycosylated and glycosylated forms of the LDL Receptor
gene symbol :
LDLR
Antibody validation :
Knockout/Knockdown
applications :
Immunohistochemistry-Paraffin,IF/IHC,Simple Western,Western Blot,In vitro assay,Immunocytochemistry/ Immunofluorescence,Immunohistochemistry,Knockout Validated
USD :
519 USD
alt names :
FH, FHC, LDL receptor, LDLCQ2, low density lipoprotein receptor, low-density lipoprotein receptor, low-density lipoprotein receptor class A domain-containing protein 3
storage :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.